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Summer Research at the University of Minnesota Medical School

明尼苏达大学医学院暑期研究

基本信息

批准号：
10418721
负责人：
COLIN R CAMPBELL
金额：
$ 18.66万
依托单位：
UNIVERSITY OF MINNESOTA
依托单位国家：
美国
项目类别：
财政年份：
2007
资助国家：
美国
起止时间：
2007-05-01 至 2024-05-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10418721
关键词：
Address Admission activity Affect Area Bachelor&apos s Degree Behavioral Research Biological Sciences Biomedical Research Cardiovascular Diseases Cities Clinical Clinical Research Clinical Trials Communication Credentialing Data Degree program Development Disabled Persons Disadvantaged Doctor of Philosophy Education Education Projects Educational Activities Educational workshop Enrollment Environment Ethnic group Faculty Feedback Funding Future Goals Grain Health Sciences Hematological Disease Individual Institution Interview Laboratories Letters Literature Lung diseases Measures Medical Mentors Minnesota Mission Monitor National Heart, Lung, and Blood Institute Participant Physicians Preparation Prevention Puerto Rico Race Recommendation Recording of previous events Research Research Project Grants Research Training Resources Scholarship Schools Scientist Series Societies Student recruitment Students Talents Techniques Training Training Activity Training Programs Twin Multiple Birth Underrepresented Populations Underrepresented Students Universities base career clinical practice cohort college demographics design experience faculty mentor health disparity human capital improved innovation interest medical schools member novel posters prevent programs recruit skill acquisition skills stem student mentoring success summer research symposium undergraduate student

项目摘要

Abstract The long-term goal of this program is to harness institutional resources, both physical and human capital to support a vibrant, challenging and supportive research training program that can contribute to the development of a future biomedical scientific workforce that more broadly represents the diversity of our society. It is clear to us that the current lack of diversity in this workforce, particularly at the doctoral and professional level, prevents us from reaching our full potential to enhance the prevention and treatment of cardiovascular, lung and blood diseases. Challenges stemming from this lack of diversity include difficulty in recruiting individuals from underrepresented groups into clinical trials, and efforts to eliminate health disparities that disproportionately affect individuals from under-represented groups. Of particular concern, given the rapidly changing demographics in the US, is the reality that a lack of diversity narrows the pipeline and perspectives of talented individuals who can advance the National Heart Lung and Blood Institute’s scientific mission. To address this long-term goal, we have developed a number of short-term objectives: 1. Recruit a diverse, academically outstanding cohort of students from across the US and Puerto Rico to the University of Minnesota, and provide student participants with a program faculty-mentored independent research opportunity, 2. Maintain a previously developed innovative research-training module devoted to recruiting and training a cohort of students, selected from participant pool, who are committed to the pursuit of a combined MD-PhD degree, and 3. Develop a series of workshops designed to provide program participants with skills needed to successfully compete for admission to a doctoral programs. Our working hypothesis is that the training provided to these participants will provide them with the skills, experience, and ambition required to successfully compete for admission to PhD, MD-PhD and other advanced degree programs. The proposed research training program will provide 22 undergraduate students recruited from across the US and Puerto Rico to an intensive 10-week summer independent research experience in the laboratories of program faculty mentors on the University of Minnesota’s Twin Cities campus. It is anticipated that six of these students will participate in the aforementioned combined MD-PhD module. All students selected will have had between one and four years of university education at the baccalaureate level. To be eligible students must not yet have received their baccalaureate degree, and must self-identify as a member of an underrepresented racial or ethnic group, or be disabled, or disadvantaged. The ultimate measure of the success of this training program will be it’s ability to assist program participants in becoming members of the biomedical scientific workforce, pursuing research in cardiovascular, lung or blood diseases. It is anticipated that between a third and a half of student participants will go on to pursue advanced research degrees in the biological sciences upon completion of their baccalaureate degree programs.

摘要该计划的长期目标是利用机构资源，包括物质和人力资本，支持一个充满活力，具有挑战性和支持性的研究培训计划，可以促进发展未来的生物医学科学劳动力，更广泛地代表我们社会的多样性。很清楚我们认为，目前缺乏多样性的劳动力，特别是在博士和专业水平，防止我们充分发挥潜力，加强预防和治疗心血管，肺和血液疾病缺乏多样性带来的挑战包括难以从代表性不足的群体进入临床试验，并努力消除不成比例的健康差距，影响代表性不足群体的个人。特别令人关切的是，在美国，缺乏多样性缩小了人才的渠道和视角，个人谁可以推进国家心肺和血液研究所的科学使命。为了实现这一长期目标，我们制定了一些短期目标：1。招募一个多样化的，来自美国各地和波多黎各的学术优秀的学生队列的大学明尼苏达州，并为学生参与者提供一个计划教师指导的独立研究机会，2.维持以前开发的创新研究培训模块，专门用于征聘和培训一批学生，从参与者库中选出，他们致力于追求综合博士学位，3。开发一系列旨在为计划参与者提供技能的研讨会需要成功地竞争进入博士课程。我们的假设是为这些参与者提供的培训将为他们提供所需的技能、经验和雄心，成功竞争博士，MD-PhD和其他高级学位课程的录取。拟议的研究培训计划将提供22名从美国各地招募的本科生和波多黎各的实验室进行为期10周的密集夏季独立研究经验，明尼苏达大学双子城校区的项目教师导师。预计其中6个学生将参加上述MD-PhD组合模块。所有被选中的学生一至四年的学士学位大学教育。要成为合格的学生，然而，已经获得学士学位，必须自我认同为代表性不足的一员，种族或族裔群体，或残疾，或处于不利地位。这个培训计划成功的最终衡量标准将是它能够帮助计划参与者成为生物医学科学工作者的一员，从事心血管，肺或血液研究疾病预计三分之一至一半的学生将继续追求高级在完成学士学位课程后获得生物科学研究学位。

项目成果

期刊论文数量（7）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

Endothelial TLR4 Expression Mediates Vaso-Occlusive Crisis in Sickle Cell Disease.

DOI：
10.3389/fimmu.2020.613278
发表时间：
2020
期刊：
Frontiers in immunology
影响因子：
7.3
作者：
Beckman JD;Abdullah F;Chen C;Kirchner R;Rivera-Rodriguez D;Kiser ZM;Nguyen A;Zhang P;Nguyen J;Hebbel RP;Belcher JD;Vercellotti GM
通讯作者：
Vercellotti GM

Anti-proliferative effects of simocyclinone D8 (SD8), a novel catalytic inhibitor of topoisomerase II.

西莫环酮 D8 (SD8) 的抗增殖作用，一种新型拓扑异构酶 II 催化抑制剂。

DOI：
10.1007/s10637-008-9209-1
发表时间：
2010
期刊：
Investigational new drugs
影响因子：
3.4
作者：
Sadiq,AhadA;Patel,ManishR;Jacobson,BlakeA;Escobedo,Marco;Ellis,Keith;Oppegard,LisaM;Hiasa,Hiroshi;Kratzke,RobertA
通讯作者：
Kratzke,RobertA

Nicotinic acid adenine dinucleotide phosphate analogues containing substituted nicotinic acid: effect of modification on Ca(2+) release.