Institutional Clinical and Translational Science Award

联系人 PD/PI：FITZGERALD、GARRET A 总体 摘要/总结 转化医学和治疗研究所是 CTSA 的学术所在地 佩恩。在过去的十五年里，ITMAT 的目标一直是并且仍然是 (i) 增加能够在证明之间进行研究的调查人员数量 细胞和模型系统中的概念以及（ii）阐明人类生理学机制， 通过少数人的强烈表型分析来确定疾病或药物作用。两人 我们的 CTSA 的首要任务是培育转化疗法领域并弥合 从儿科到成人的划分跨越了整个临床和转化科学领域。这个 部分描述了这些优先事项如何影响该 CTSA 中心的发展并概述 我们对未来资助期的计划。 项目总结/摘要第 136 页 联系人 PD/PI：FITZGERALD、GARRET A 总体 叙事 转化医学和治疗研究所是 CTSA 的学术所在地 佩恩。在过去十年中，ITMAT 的具体目标始终是 (i) 提高 能够在细胞概念验证之间进行研究的研究人员数量 和模型系统以及（ii）阐明人类生理学、疾病或 通过在少数人群中进行强烈的表型分析来确定药物作用。

Contact PD/PI: FITZGERALD, GARRET A OVERALL ABSTRACT/SUMMARY The Institute for Translational Medicine and Therapeutics is the academic home for the CTSA in Penn. For the past decade and a half the objectives of ITMAT have been and remain (i) to increase the number of investigators capable of pursuing their research between proof of concept in cells and model systems and (ii) elucidation of the mechanisms of human physiology, disease or drug action through intense phenotyping in small numbers of people. The two priorities of our CTSA are to foster the field of translational therapeutics and to bridge the pediatric to adult divide across the entire spectrum of clinical and translational science. This section describes how these priorities have influenced the growth of this CTSA Hub and outlines our plans for the coming funding period. Project Summary/Abstract Page 136 Contact PD/PI: FITZGERALD, GARRET A OVERALL NARRATIVE The Institute for Translational Medicine and Therapeutics is the academic home for the CTSA in Penn. For the past decade the specific aims of ITMAT have been and remain (i) to increase the number of investigators capable of pursuing their research between proof of concept in cells and model systems and (ii) elucidation of the mechanisms of human physiology, disease or drug action through intense phenotyping in small numbers of people.