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Research Infrastructure Core

研究基础设施核心

基本信息

批准号：
10426329
负责人：
Song Gao
金额：
$ 58.82万
依托单位：
TEXAS SOUTHERN UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
1986
资助国家：
美国
起止时间：
1986-09-30 至 2025-05-31
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10426329
关键词：
Address Animals Applications Grants Area Award Bioinformatics Biological Products Biomedical Research Biometry Clinical Sciences Collaborations Core Facility Development Educational workshop Environment Equipment Evaluation Event Faculty Fees Formulation Funding Grant Health care facility Human Resources Infrastructure Institution Interdisciplinary Study International Intervention Laboratories Lead Legal patent Link Methionine Methodology Minority Health Research Molecular Molecular Biology Molecular and Cellular Biology Peer Review Peptide Hydrolases Pharmacology Pharmacy facility Pilot Projects Productivity Publishing Reproducibility Research Research Design Research Infrastructure Research Institute Research Methodology Research Personnel Research Project Grants Research Support Resources Reverse Transcriptase Polymerase Chain Reaction Services Structure Techniques Texas Toxic effect Training Training Programs Translational Research Translations Underrepresented Minority United States National Institutes of Health Universities Work animal care antimicrobial drug cancer prevention career castration resistant prostate cancer chemotherapeutic agent community engagement data management drug candidate drug development drug metabolism environmental toxicology faculty research falls genetic analysis genome editing gulf coast improved innovation instrument lead optimization member minority health new therapeutic target novel pharmacokinetics and pharmacodynamics pre-clinical preclinical development programs recruit skills symposium synergism web site

项目摘要

Abstract Texas Southern University (TSU), the nation’s second largest HBCU, has been continuously supported by the RCMI program for many years, and has significantly strengthened our research environment. In the last RCMI funding cycle, we successfully developed and deployed three core facilities including Pharmacology, Molecular Biology, and Environmental Toxicity. These advances have led to productive collaborations on projects including new drug targets, new lead compounds, preclinical lead optimization, and formulation. However, there is an unmet need to enhance our research resources and services to include study design, methodology development, data management, specialized laboratory techniques (e.g., genome editing, animal work skills), instrument utilization, and collaboration networks. In this renewal application, we propose to establish a Research Infrastructure Core (RIC) in the Center for Biomedical and Minority Health Research (CBMHR) to support research and pilot projects by providing these enhanced services (in addition to research infrastructure made available through previous RCMI funding) to TSU and external users and to facilitate new collaborations in biomedical research. The specific aims are: Support CBMHR research and pilot projects and provide services to users to enhance quality and productivity of biomedical research (Aim 1); Develop and validate laboratory techniques to support CBMHR research and pilot projects and provide trainings to internal and external users (Aim 2); and Facilitate networking to increase collaborative research projects and grant applications (Aim 3). We propose to form a faculty expert team, consultant team, and recruit skilled staff to support our users in six areas in which we have great expertise and credibility. The involved personnel, including core director, co- director, faculty expert team members, and consultants, will be experts in the key research areas. We also propose to facilitate new collaborations with experts in other institutions to integrate research resources across the Houston area. Additionally, we will integrate core information including fee structures into the CBMHR website to promote our services. Innovations of this proposed RIC include novel research methodology development, collaborative research projects and grant applications, and collaborative synergism. We expect that this proposed RIC will significantly enhance TSU’s research capability in biomedical and minority health research so that more competitive grant proposals can be submitted to different agencies (e.g., NIH) and more faculty, especially junior faculty, will be successful in their academic career.

摘要