Multidisciplinary Visual Sciences Training Program

在过去的5年里，基础视觉科学和临床视觉科学发生了惊人的融合。基本信息 光遗传学、转录学、干细胞生物学、病毒转导、血管生成和成像研究进展 都已经在临床环境中得到了应用。这个项目的基本原理是，理想的视觉科学家 未来，今天的实习生，需要有多学科的背景，以便精通这两个基础 科学和临床应用。西北大学多学科视野的主要目标 培训计划是为独立从事视觉研究的博士后和博士后培训人员做准备 广义的定义包括：包括角膜和Schlemm‘s在内的前眼的疾病和功能 神经管；视网膜神经元和血管系统的疾病和机制；以及由视网膜中央处理 靶区包括那些调节瞳孔反应、调节和昼夜节律牵引的区域。这 Proposal通过整合实验室利用西北大学现有的多学科研究基地 为了训练的目的变成一个有凝聚力的单位。这16位教授提供细胞和分子方面的研究培训 生物学、视觉系统神经生物学、遗传学、高级显微镜、干细胞生物学和类器官 培养，前部和后部眼部疾病，以及基于证据的治疗结果分析和 医疗保健服务。资助3名博士前候选人，在他们开始全日制论文后 需要1名处于早期或中期培训阶段的博士后实习生。博士后 受训人员的招聘依据是课程成绩、轮换评价和与拟议的 西北大学综合神经科学(NUIN)项目的论文研究 跨部门生物科学(IBIS)计划、Driskill生命科学研究生计划(DGP)、 和生物医学工程(BME)研究生课程。最多支持两个文档前和文档后 几年的时间取决于研究进展。主任和指导委员会评估和挑选受训人员 从符合条件的博士后和博士后中选出。培训方案还对学员进行以下方面的道德教育 科学和负责任的研究行为。主要的重点是从以下人员中招聘受训人员- 代表少数群体进行视觉研究。每个受训者的计划由受训者决定， 负责制定个人发展计划的校长和指导委员会。项目总监是 史蒂文·H·德弗里斯，医学博士，教授，大卫·E·肖赫，眼科和生理学教授。在……里面 除了研究培训，该项目还提供了一门课程，其中包括两门关于血管的正式课程 生物学和视网膜回路(博士前实习生必须至少选择一个)，第二季度的演示系列题为 视觉高级主题，全国知名研究人员的特邀讲座，以及研究日。长的- 学期目标是教育受训人员，他们将继续作为独立的、多产的和道德的调查人员 谁将解决视觉研究中的国家优先事项。

The past 5 years have witnessed a stunning convergence between basic and clinical visual science. Basic advances in optogenetics, transcriptomics, stem cell biology, viral transduction, angiogenesis, and imaging have all seen application in the clinical setting. The rationale for this program is that the ideal visual scientist of the future, today’s trainee, needs to have a multidisciplinary background so as to be well-versed in both basic science and clinical applications. The major aim of the Northwestern University Multidisciplinary Vision Training Program is to prepare pre- and postdoctoral trainees for independent careers in vision research broadly defined to include: diseases and functions of the anterior eye including the cornea and Schlemm’s canal; diseases and mechanisms of the retinal neurons and vasculature; and, processing by central retinal target areas including those mediating pupillary responses, accommodation, and circadian entrainment. This proposal leverages the existing multidisciplinary research base at Northwestern University by integrating labs into a cohesive unit for the purposes of training. The 16 preceptors offer research training in cell and molecular biology, neurobiology of the visual system, genetics, advanced microscopy, stem cell biology and organoid culture, diseases of the anterior and posterior eye, and evidenced based analysis of treatment outcomes and healthcare delivery. Funding to support 3 predoctoral candidates, after they have begun full time thesis research, and 1 postdoctoral trainee, in the early or middle stages of training, is requested. The predoctoral trainees are recruited on the basis of course performance, rotation evaluations, and relevance of the proposed dissertation research from the Northwestern University Integrated Neuroscience (NUIN) program, the Interdepartmental Biological Sciences (IBiS) program, the Driskill Graduate Program in Life Sciences (DGP), and the Biomedical Engineering (BME) Graduate Program. Pre- and post-docs are supported for up to two years contingent on research progress. The Director and Steering Committee evaluates and selects trainees from among the eligible pre- and post-docs. The training program also educates trainees in the ethics of science and responsible conduct of research. Major emphasis is placed on recruiting trainees from under- represented minority groups to vision research. The program for each trainee is determined by the trainee, preceptor, and Steering Committee who formulate an individual development plan. The Program Director is Steven H. DeVries, MD, PhD, Professor and David E. Shoch Chair of Ophthalmology and Physiology. In addition to research training, the program offers a curriculum that includes two formal courses on vascular biology and retinal circuits (pre-doc trainees must choose at least one), a 2 quarter presentation series entitled Advanced Topics in Vision, invited lectures by nationally known researchers, and a Research Day. The long- term objective is to educate trainees who will continue as independent, productive, and ethical investigators and who will address national priorities in vision research.