Defining the structural basis of lipid mediated T cell immunity

该项目旨在开展发现研究，以探索脂质在T细胞免疫中作用的分子机制：一个具有巨大生物学意义的新兴领域。预期的目标是通过使用包括结构生物学、质谱学、生物物理学和细胞免疫学在内的多学科方法，在生命科学领域产生新的知识，以获得对控制脂质介导的免疫的分子决定因素的基本见解。该项目的预期成果和好处包括建立国际和跨学科合作，以提高国家研究能力，并显著促进生物科学核心知识的发展。

This project aims to undertake discovery research to investigate the molecular mechanisms underpinning the role of lipids in T cell immunity: an emerging area of immense biological significance. The anticipated goal is to generate new knowledge in the areas of the life sciences, by using a multidisciplinary approach that includes structural biology, mass spectrometry, biophysics, and cellular immunology, to gain fundamental insight into molecular determinants that govern lipid mediated immunity. Expected outcomes and benefits of this project include building international and interdisciplinary collaborations to enhance national research capacity, and provide marked advancement of core knowledge in the biological sciences.