Rutgers-NYU Center for Asian Health Promotion and Equity

总体-摘要 作为对RFA-MD-21-007的回应，我们建议成立罗格斯-纽约大学亚洲健康促进与公平中心， （CAHPE）推进亚洲人共病心脏代谢疾病和心理健康的跨学科研究 成年人了目前与心脏和精神的关系存在显着差异，BMI的阈值较低 亚洲人和不成比例的差距与心脏代谢疾病和心理健康。这样的 研究、人口和调查人员的重要重点将为社区的实践和政策提供信息， 区域和国家各级。亚洲人是增长最快但最未得到充分研究的美国少数族裔群体，人数为2300万 从2010年到2019年增长26%。然而，在过去10年中，NIH研究资金的不到1%集中在 美国亚裔人口。此外，这一人群经历了“亚洲Parkman”：而平均而言，美国 亚洲人，是收入最高的人，受教育程度最高，更多的亚洲人，特别是老年人， 生活在贫困线以下的人，不太可能参与生物医学研究， 与白色美国人相比的差距。这些卫生不公平现象因医疗保健的异质性而进一步复杂化， 这些移民人口，特别是在文化，宗教，语言，性别认同和创伤方面， 暴露，其中许多挑战了我们对“模范少数民族”刻板印象的假设。 在对少数民族人口进行了20年严格的老龄化研究以及 成功的学术成就，我们已经利用强大的跨学科合作伙伴关系， 多个学术和社区机构，以建立一个中心，旨在培养下一代的多样化 研究人员在培育环境，有利于成功，促进高度相关和严格的 在美国亚洲人中进行的心脏代谢和心理健康结果的转化研究。强 在300万美元的配套资金的机构支持下，我们的中心将有五个相互关联的目标：1） 提供领导力、组织沟通和评估系统，旨在实现 支持高质量和持久的心脏代谢和心理健康跨学科研究的目标 2）每年征集指南并选择6项试点研究; 3）实施 三个跨学科，转化和协同R 01类项目，具体重点是：营养，积极 情感和痴呆症护理干预措施，以多方面针对不同的亚洲高危人群; 4） 加强、跟踪和评估现有的基础设施，以支持和同步试点项目和中心项目; 5）将这些调查结果传播到地方、区域和国家各级，以便为未来的设计提供信息。 预防/干预研究商品。本申请的总体目标反映了以下方面的协同工作： 管理核心（AC）、研究者发展核心（IDC）、社区参与核心（CEC），以及 研究项目。

Overall – Abstract In response to RFA-MD-21-007, we propose the Rutgers-NYU Center for Asian Health Promotion and Equity (CAHPE) to advance interdisciplinary research on comorbid cardiometabolic disease and mental health of Asian adults. There are currently significant disparities in relationship to Heart and Mind, with lower thresholds for BMI for Asians and disproportionate disparities related to cardiometabolic disease and mental health. Such an important focus in research, population and investigators will inform both practice and policy at community, regional and national levels. Asians are the fastest growing yet most understudied US minority group at 23 million people and growing 26% from 2010-2019. Yet, < 1% of NIH research funding in the last 10 years were focused on US Asian populations. Moreover, this population experiences the “Asian Paradox”: while on average, US Asians, are the highest-income earners and the most highly educated, more Asians, especially older adults, live below the poverty line, are less likely to participate in biomedical research, and suffer disproportional health disparities compared to white Americans. These health inequities are further complicated by the heterogeneity of these immigrant populations, especially with respect to culture, religion, language, sexual identity, and trauma exposure, many of which challenge our assumptions about the “model minority” stereotype. Building on two decades of rigorous aging research in minority populations and track records of successful academic achievements, we have leveraged strong existing transdisciplinary partnerships across multiple academic and community institutions to build a center designed to foster the next generation of diverse researchers in a nurturing environment that is conducive to success and promotes highly relevant and rigorous translational research on cardiometabolic and mental health outcomes among US Asians. With strong institutional support of $3 million in matching funds, our Center will have five inter-connected aims: 1) Provide leadership, organizational communication, and evaluation systems designed to achieve the overarching goals of supporting high quality and enduring inter-disciplinary research on cardiometabolic and mental health outcomes among Asian adults; 2) Guide solicitation and selection of 6 pilot studies per year; 3) Implement the three interdisciplinary, translational, and synergistic R01-like projects with specific focus on: Nutritional, Positive Affect, and Dementia Caregiving Interventions to multi-prong target diverse Asian population at high risk; 4) Enhance, track, and evaluate existing infrastructure to support and synchronize the pilot and center projects; and 5) Disseminate these findings to the local, regional, and national levels in order to inform the design of future prevention/intervention research commodities. The overall aims of this application reflect the synergistic work of the Administrative Core (AC), Investigator Development Core (IDC), Community Engagement Core (CEC), and research projects.