Rutgers-NYU Center for Asian Health Promotion and Equity

整体-摘要 为响应RFA-MD-21-007，我们建议成立罗格斯-纽约大学亚洲健康促进和公平中心 (CAHPE)将推进亚洲人心脏代谢性疾病与心理健康的跨学科研究 成年人。目前，在与心脏和精神的关系上存在显著差异，BMI的门槛较低 对于亚洲人来说，与心脏代谢性疾病和精神健康相关的不成比例的差异。这样的一种 重要的研究重点，人口和调查人员将为社区的实践和政策提供信息， 区域和国家两级。亚洲人是增长最快、但最不受关注的美国少数民族，有2300万人 从2010年到2019年增长了26%。然而，在过去的10年里，美国国立卫生研究院1%的研究资金集中在 关于美国亚裔人口的。此外，这部分人口还经历了“亚洲悖论”：平均而言，美国 亚洲人收入最高，受教育程度最高，更多的亚洲人，特别是老年人，生活在 贫困线以下，不太可能参与生物医学研究，并遭受不成比例的健康 与美国白人相比的差距。这些健康不平等由于异质性而变得更加复杂 这些移民人口，特别是在文化、宗教、语言、性认同和创伤方面 曝光，其中许多挑战了我们对“模范少数族裔”刻板印象的假设。 建立在20年来对少数族裔人口的严格老龄化研究和 成功的学术成就，我们利用现有的跨学科的强大合作伙伴关系 多个学术和社区机构建设一个中心，旨在培养下一代多样化的 在有利于成功并促进高度相关和严谨的培养环境中的研究人员 美国亚洲人心脏代谢和心理健康结果的翻译研究。带着强大的 300万美元的机构支持，我们的中心将有五个相互关联的目标：1) 提供旨在实现总体目标的领导力、组织沟通和评估系统 支持高质量和持久的心脏代谢和心理健康跨学科研究的目标 在亚洲成年人中取得的成果；2)每年征集和选择6项试点研究的指南；3)实施 三个跨学科、翻译和协同的类似R01的项目，具体侧重于：营养、积极 对多管齐下的亚洲高危人群进行情感、痴呆护理干预；4) 加强、跟踪和评估现有基础设施，以支持和同步试点项目和中心项目； 以及5)将这些调查结果传播到地方、区域和国家各级，以便为未来的设计提供信息 预防/干预研究商品。本应用程序的总体目标反映了以下各项的协同工作 管理核心(AC)、调查员开发核心(IDC)、社区参与核心(CEC)和 研究项目。

Overall – Abstract In response to RFA-MD-21-007, we propose the Rutgers-NYU Center for Asian Health Promotion and Equity (CAHPE) to advance interdisciplinary research on comorbid cardiometabolic disease and mental health of Asian adults. There are currently significant disparities in relationship to Heart and Mind, with lower thresholds for BMI for Asians and disproportionate disparities related to cardiometabolic disease and mental health. Such an important focus in research, population and investigators will inform both practice and policy at community, regional and national levels. Asians are the fastest growing yet most understudied US minority group at 23 million people and growing 26% from 2010-2019. Yet, < 1% of NIH research funding in the last 10 years were focused on US Asian populations. Moreover, this population experiences the “Asian Paradox”: while on average, US Asians, are the highest-income earners and the most highly educated, more Asians, especially older adults, live below the poverty line, are less likely to participate in biomedical research, and suffer disproportional health disparities compared to white Americans. These health inequities are further complicated by the heterogeneity of these immigrant populations, especially with respect to culture, religion, language, sexual identity, and trauma exposure, many of which challenge our assumptions about the “model minority” stereotype. Building on two decades of rigorous aging research in minority populations and track records of successful academic achievements, we have leveraged strong existing transdisciplinary partnerships across multiple academic and community institutions to build a center designed to foster the next generation of diverse researchers in a nurturing environment that is conducive to success and promotes highly relevant and rigorous translational research on cardiometabolic and mental health outcomes among US Asians. With strong institutional support of $3 million in matching funds, our Center will have five inter-connected aims: 1) Provide leadership, organizational communication, and evaluation systems designed to achieve the overarching goals of supporting high quality and enduring inter-disciplinary research on cardiometabolic and mental health outcomes among Asian adults; 2) Guide solicitation and selection of 6 pilot studies per year; 3) Implement the three interdisciplinary, translational, and synergistic R01-like projects with specific focus on: Nutritional, Positive Affect, and Dementia Caregiving Interventions to multi-prong target diverse Asian population at high risk; 4) Enhance, track, and evaluate existing infrastructure to support and synchronize the pilot and center projects; and 5) Disseminate these findings to the local, regional, and national levels in order to inform the design of future prevention/intervention research commodities. The overall aims of this application reflect the synergistic work of the Administrative Core (AC), Investigator Development Core (IDC), Community Engagement Core (CEC), and research projects.