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Structural Genomics Centers for Infectious Diseases

Structural Genomics Centers for Infectious Diseases
传染病结构基因组学中心
批准号：
10439427
负责人：
Karla J F Satchell
金额：
$40.55万
依托单位：
NORTHWESTERN UNIVERSITY AT CHICAGO
依托单位国家：
美国
项目类别：
财政年份：
2017
资助国家：
美国
项目状态：
已结题
起止时间：
2017-09-01 至 2022-08-31
来源：
https://reporter.nih.gov/project-details/10439427
关键词：
3-DimensionalAlphavirusBasic ScienceBiologicalBiomedical ResearchCategoriesEmerging Communicable DiseasesGenomic Centers for Infectious DiseasesGoalsMolecularNational Institute of Allergy and Infectious DiseaseOrganismProteinsResearch Project GrantsResearch SupportRoleStructureTechnologypathogenpriority pathogenprogramsstructural biologystructural genomicsthree dimensional structure

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中文摘要
翻译
传染病结构基因组学中心的目标是应用最先进的高通量结构生物学技术，通过实验表征 NIAID A-C 类优先病原体清单上的目标蛋白以及引起新出现和重新出现传染病的生物体的三维原子结构。该计划还支持利用 3D 结构信息和实验方法更好地表征蛋白质靶标的分子功能作用的研究项目。该中心的主要关注点是病原体蛋白，这些蛋白有望发挥重要的生物学作用并对生物医学研究产生潜在影响。
英文摘要
The goal of the Structural Genomics Centers for Infectious Diseases is to apply state-of-the-art, high-throughput structural biology technologies to experimentally characterize the three-dimensional atomic structure of targeted proteins on the NIAID Category A-C priority pathogens list and organisms causing emerging and re-emerging infectious diseases. This program also supports research projects that utilize the 3D structure information and experimental approaches to better characterize the molecular functional role of protein targets. The primary focus of the Center is pathogen proteins that are expected to have an important biological role and a potential impact on biomedical research.
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Structural Genomics Centers for Infectious Diseases
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