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Digitalisation of canine elbow disease surgery

Digitalisation of canine elbow disease surgery
犬肘部疾病手术的数字化
批准号:
10072913
负责人:
金额:
$12.68万
依托单位:
依托单位国家:
英国
项目类别:
Launchpad
财政年份:
2023
资助国家:
英国
项目状态:
未结题
起止时间:
2023 至 --

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中文摘要
翻译
该项目将为犬肘发育不良(CED)创造一个成功的外科治疗和数字化工作流程。CED包括许多导致剧烈疼痛和关节炎的病理和畸形。许多品种的狗都容易患CED,如拉布拉多犬、金毛猎犬、罗特韦尔犬、德国牧羊犬、伯恩斯山地犬、纽芬兰犬和短毛猎犬。虽然大多数治疗方法都是保守的,通过控制体重、适量运动、消炎和止痛药来将疼痛降至最低,但30%的病例需要手术治疗,这些病例需要关节镜下清创、负载转移和部分/全部肘关节置换。与人类的类似手术相比,手术并发症很高。需要解决动物和人类之间的待遇差异。该项目建立在Fusion Implants进行的获奖UOL研究(莱斯利·沃恩2022年奖)的基础上,其中研究了CED的科学和工程,并开发了定制植入物的概念。在这个项目中,Fusion Implants将把PHD结果数字化,增强从数据采集到影院的工作流程并使其自动化,从而带来简化、快速和有效的手术。技术挑战是创建一条价值链,将数字技术、数字测角、基于CT的分层、算法开发和3D打印植入物/器械制造结合到一个单一的工作流程中,从而推进治疗、加快诊断和手术,从而改善患者的结果。
英文摘要
The project will create a successful surgical treatment and digital workflow for canine elbow dysplasia (CED). CED covers numerous pathologies and deformities causing severe pain and arthritis. Many breeds of dog are predisposed to CED, such as Labrador, Golden retrievers, Rottweilers, German Shepherd Dogs, Bernese Mountain Dogs, Newfoundland and Basset Hounds.Although most treatments are conservative and minimise pain by using weight control, exercise moderation, anti-inflammatories and painkillers, surgical intervention is required in 30% of cases with arthroscopic debridement, load transfer and partial/total elbow replacement being the remedies.Surgical complications are high in comparison to similar operations on humans, this disparity between the treatment of animals and humans needs to be addressed.The project builds on award-winning UoL research (Leslie Vaughan Prize 2022) undertaken by Fusion Implants in which the science and engineering of CED were studied and custom implant concepts developed. In this project, Fusion Implants will digitalise the PhD results enhancing and automating workflows from data capture to theatre, leading to simplified, more rapid and effective surgeries.The technological challenge is to create a value chain whereby digital technologies, digital goniometry, CT-based stratification, algorithm development and 3D print implant/instrument manufacture are combined into a single workflow which advances treatment, accelerates diagnosis, and surgery, improving outcomes for patients.
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α-酮戊二酸调控ACMSD介导犬尿氨酸通路代谢重编程在年龄相关性听力损失中的作用及机制研究
  • 批准号:
    82371150
  • 项目类别:
    面上项目
  • 资助金额:
    49.00万元
  • 批准年份:
    2023
  • 负责人:
    侯书乐
  • 依托单位: