Multidisciplinary Pulmonary and Critical Care Training Program

这是一份竞争性续签申请，要求继续获得T32奖励资金，以支持多学科 犹他大学医学院肺部和危重护理研究培训计划。 该培训计划的总体目标是帮助培养下一代医学和博士科学家 在肺部和重症监护医学的广泛领域提高我们对疾病过程的知识，以及 将这一知识转化为照顾我们的病人。到目前为止，这个培训计划非常成功； 我们的绝大多数学员都有优秀的发表记录，已经进入了积极的研究阶段 在学术医学方面的职业，大多数人已经获得了资金来支持他们的研究。这些实习生 包括医学博士和博士研究人员，解决基础和临床研究中的问题。该计划 该培训计划的教职员工由来自不同学科的15名成功的科学家组成，包括 细胞和分子生物学、定量研究和建模、结果研究和人类遗传学； 有培训年轻调查人员的丰富历史，并参与协作、翻译和交叉- 学科研究项目。我们提议继续支助4个实习生职位(医学博士或博士)，担任以下职位： 博士生培训，至少有2年的培训计划。实习生是从奖学金中招募的。 肺和重症护理医学计划或来自个人导师的研究计划；他们 可以选择基础研究或临床研究路径。培训计划的主要组成部分 包括有指导的个人研究项目、与受训者所选领域相关的教学课程以及 旨在拓宽受训人员研究视野的课程和经验。临床实习生 研究路径通常注册临床调查理学硕士学位课程。所有受训人员 将参加课程以增加在研究职业生涯中取得长期成功的机会(科学写作，格兰特 写作)，以负责任的研究行为，并提高研究的严谨性和重复性。一个 该计划的重要优先事项是为学员在多学科团队中发挥作用做好准备。因此，a 该计划的主要特点是使用由导师组成的个人指导委员会，以及 包括基础和临床研究人员。这些委员会将继续让受训者接触多学科 解决关键问题的方法，鼓励受训者超越其项目的国内纪律。基座 关于犹他大学学员的特殊机构优势，将有广泛的机会 培养遗传学、生物医学信息学、纳米技术、老年病学和 环境因素对肺部疾病的影响。这项正在进行的计划将使年轻科学家具备追求未来的能力 肺部和重症监护医学方面的研究，重点是来自 机械论的发现和多学科的方法。

This is a competitive renewal application for continued T32 award funding to support a Multidisciplinary Training Program in Pulmonary and Critical Care Research at the University of Utah School of Medicine. The overall goal of this Training Program is to help develop the next generation of MD and PhD scientists to advance our knowledge of disease processes in the broad arena of pulmonary and critical care medicine, and to translate this knowledge to care of our patients. This Training Program has been very successful to date; the great majority of our trainees have excellent publication records, have advanced into active research careers in academic medicine, and most have obtained funding to support their research. These trainees include both MD and PhD investigators, addressing questions in basic and clinical research. The Program faculty for this training program consists of 15 successful scientists drawn from a range of disciplines, including cell and molecular biology, quantitative research and modeling, outcomes research and human genetics; all have a strong history of training young investigators and are involved in collaborative translational and cross- disciplinary research projects. We propose continued support of 4 trainee positions (MD or PhD) for post- doctoral training, with a minimum of 2 years in the training program. Trainees are recruited from the fellowship program in Pulmonary and Critical Care Medicine or from the research programs of individual mentors; they may elect either a basic research or clinical research pathway. Key components of the Training Program include a mentored individual research project, didactic courses relevant to the trainee’s chosen field and courses and experiences intended to broaden the trainee’s research perspective. Trainees on the clinical research pathway typically enroll in a Master of Science in Clinical Investigation degree program. All trainees will take courses to enhance opportunities for long-term success in a research career (Scientific Writing, Grant Writing), in the Responsible Conduct of Research and to enhance Rigor and Reproducibility in research. An important priority for this program is to prepare trainees to function within multidisciplinary teams. Therefore, a central feature of the Program is the use of individual mentorship committees composed of the mentor, and both basic and clinical researchers. These committees will continually expose the trainees to multidisciplinary approaches to key problems, encouraging trainees to look beyond the home discipline of their projects. Based on the special institutional strengths at the University of Utah trainees, will have extensive opportunities to develop useful competencies in genetics, biomedical informatics, nanotechnology, geriatrics and environmental contributions to lung disease. This ongoing program will equip young scientists to pursue future investigations in pulmonary and critical care medicine, with emphasis on translational science flowing from mechanistic discoveries and multidisciplinary approaches.