Neural Imaging Module

项目摘要 目前的视觉研究依赖于各种各样的成像技术和模式，从基于MRI的 活体大脑的成像，检测神经元示踪剂，重建已经被 组织化学处理。然而，广泛的此类活动所需的资源和专门知识 技术往往超出了个别实验室的范围。神经成像模块旨在 满足这一需要，为调查人员提供广泛的支助，包括使用验尸前和验尸后技术 to visualize可视化brain脑tissue组织.具体来说，神经成像模块（1）支持猴子的死前研究， 如功能磁共振成像和CT扫描为基础的方法，用于指导生理实验;（2）协助死后 啮齿动物和猴子的实验，包括特定神经元标记物的染色， 生理学电极轨迹，并测试新的基于病毒的跟踪技术;以及（3）提供工具和 组织学标本分析服务，包括连续切片的对齐和 神经元和投射为了与这些服务的多样性保持一致，该单元促进了 各种各样的基于视觉的调查项目。在经验丰富的模块主任的指导下，博士。 Richard Born和模块工作人员弗拉基米尔Berezovskii博士表示， 神经成像模块将继续在推进哈佛地区的视觉研究中发挥关键作用。

Project Summary Current vision research relies on a wide variety of imaging techniques and modalities, ranging from MRI-based imaging of the living brain, to detecting a neuronal tracer, to reconstructing neurons that have been histochemically processed. However, the resources and expertise required for the wide range of such techniques can often lie outside the scope of individual laboratories. The Neural Imaging Module aims to address this need by providing extensive support to investigators using both pre- and post-mortem techniques to visualize brain tissue. Specifically, the Neural Imaging Module (1) supports pre-mortem studies in monkeys, such as fMRI and CT scan-based methods for guiding physiological experiments; (2) assists with post-mortem experiments in rodents and monkeys, including staining for specific neuronal markers, assessment of post- physiology electrode tracks, and testing of new viral-based tracing techniques; and (3) provides tools and services for analysis of histological preparations, including alignment of serial sections, and reconstructions of neurons and projections. In keeping with the diverse nature of these services, the Module has contributed to a wide variety of vision-based investigator projects. Under the experienced direction of Module Director, Dr. Richard Born, and Module staff member Dr. Vladimir Berezovskii, the expertise and services provided by the Neural Imaging Module will continue to play a critical role in advancing Harvard-area vision research.