Developing bioengineered sugar beet for aphid resistance and virus control.

开发生物工程甜菜以抵抗蚜虫和控制病毒。

• 批准号: 10076420
• 金额: $ 6.37万
• 依托单位: RESURRECT BIO LTD
• 依托单位国家: 英国
• 项目类别: Grant for R&D
• 财政年份: 2023
• 资助国家: 英国
• 起止时间: 2023 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=10076420
• 关键词: Developing; bioengineered; sugar; beet; aphid

Resurrect Bio has developed a technique for improving the immune system of crops using gene editing. They plan to use this technique to create sugar beet lines that are resistant to an aphid that spreads virus yellows, which can cause crop yields to decrease by up to 50%. The project will consist of three parts: defining the aphid's virulence proteins, decrypting the sugar beet's immune hubs, and determining which virulence proteins from the aphid are subverting the crop's natural defense response. The success of the project will allow Resurrect Bio to identify the specific immune receptors needed to make sugar beet resistant to the aphid. Targeted editing of these genes by plant breeding companies would allow farmers to reduce the use of pesticides, whilst increasing the yield of their crops.

Resurrect Bio已开发了一种使用基因编辑来改善农作物免疫系统的技术。他们计划使用这种技术来创建对蚜虫耐药性的甜菜品系，该蚜虫传播了病毒黄色，这可能导致作物产量降低高达50％。该项目将由三个部分组成：定义蚜虫的毒力蛋白，解密甜菜的免疫枢纽，并确定哪种蚜虫中哪种毒力蛋白正在颠覆作物的自然防御反应。该项目的成功将使复活的生物能够识别使甜菜对蚜虫具有耐药性所需的特定免疫受体。通过植物育种公司对这些基因进行的针对性编辑将使农民能够减少农药的使用，同时增加农作物的产量。