Tissue-engineered humanized model of the gastric tumor microenvironment to mechanistically evaluate the dynamics of combined tumor-infiltrating lymphocyte and RNA nanoparticle therapy
Tissue-engineered humanized model of the gastric tumor microenvironment to mechanistically evaluate the dynamics of combined tumor-infiltrating lymphocyte and RNA nanoparticle therapy
胃肿瘤微环境的组织工程人源化模型，用于机械评估肿瘤浸润淋巴细胞和 RNA 纳米颗粒联合治疗的动力学
批准号：
490149
负责人：
Kinsella Joseph
金额：
$76.63万
依托单位：
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2023
资助国家：
加拿大
项目状态：
未结题
起止时间：
2023-09-01 至 2028-09-01
中文摘要
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英文摘要
When cytotoxic immune cells encounter a tumor they are excluded from entering it due to the dense protein environment that the tumor builds to evade being attacked. In this proposal, we will create
personalized models of gastric cancer to study the mecha
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