Research Training Program in Cardiovascular Surgery

摘要 心血管疾病及其并发症是美国死亡和残疾的主要原因 States.外科心血管疾病对健康的影响产生了对外科研究的强烈需求。 不幸的是，心血管外科培训项目的毕业生面临着建立重建的严峻挑战。 搜索职业。利用我们在德克萨斯州医疗中心的地位，德克萨斯州最大的医疗综合体， 世界上，我们建议在心血管外科研究的博士后培训计划，将：（1）增加 进入心血管外科研究职业的医学博士和博士人才库，以及（2）为我们的学员提供 在心血管研究中取得成功和富有成效的必要技能。我们建议实现 这些目标通过每年接受两名学员（MD外科住院医师或博士）进入三个培训轨道， 每两年的时间：生物工程和生物设计，基础和转化研究，临床和 成果研究。学员可以追求多样化的研究职业培训机会，从合格的， 积极的以患者为中心的结果研究，心肌细胞再生的分子探索-但在所有 病例的重点是解决与心血管外科医生相关的临床问题。为了提供 为了提供一系列培训机会，我们从贝勒医学院（Baylor College of Medicine，Rice）招募了20名导师， 大学和休斯顿大学。[Our导师们总共有超过1620万美元的研究资金 在过去的10年里，培养了240多名博士后研究员。在三个训练轨道中，20个 导师被分组为特定的主题，如“主动脉疾病”，根据他们的专业知识和现有的颜色， 劳动关系。每个轨道允许学员完成一个学位，如硕士临床再， 搜索，通过一个既定的研究生课程在得克萨斯州医疗中心。我们的项目总监是托德 Rosengart，医学博士，Michael E. DeBakey外科系，联合主任是Scott Le- Maire，医学博士，研究副主席和Barbara Trautner，医学博士，博士，临床研究总监。我们的线索- 领导权将得到一个执行指导委员会和五个小组委员会的支持：选拔，课程， 个人发展，计划评估和教师评估。执行指导委员会将 我还收到了外部咨询委员会的意见，该委员会由三名外科医生组成，他们都曾指导过 T32训练计划[Our极具竞争力的申请人库包括2，587个MD或组合学位申请， cants到我们的普通外科住院医师研究轨道和152博士博士后研究申请人到我们的 导师的部门在休斯敦，赖斯大学，和休斯敦大学（从2017年的数字）。为了 为了确保学员的多样性，我们已经获得了美国大学机构多样性办公室的支持 和包容性，以帮助在住院医师面试日，并参加我们的选拔委员会。带去- 我们相信，这些资格为我们的计划提供了一个理想的机会，以提高人才库 高素质的医学博士和博士为心血管外科研究的高影响力竞技场做出贡献。

ABSTRACT Cardiovascular diseases and their complications are leading causes of death and disability in the United States. The health implications of surgical cardiovascular disease create a strong need for surgical research. Unfortunately, graduates of cardiovascular surgery training programs face steep challenges to establishing re- search careers. Taking advantage of our position in the Texas Medical Center, the largest medical complex in the world, we propose atpostdoctoral training program in cardiovascular surgical research that will: (1) increase the pool of MDs and PhDs who enter cardiovascular surgical research careers, and (2) provide our trainees with the skills necessary to be successful and productive in cardiovascular research. We propose to achieve these goals through accepting two trainees per year (MD surgery residents or PhDs) into three training tracks, each two years in duration: bioengineering and biodesign, basic and translational research, and clinical and outcomes research. Trainees can pursue diverse research career training opportunities—ranging from qualita- tive patient-centered outcomes research to a molecular exploration of cardiac myocyte regeneration—yet in all cases the focus is on addressing a clinical problem relevant to cardiovascular surgeons. In order to provide a range of training opportunities, we have recruited 20 mentors from Baylor College of Medicine (BCM), Rice University, and the University of Houston. [Our mentors collectively have over $16.2 million in research funding and have trained over 240 postdoctoral fellows over the past 10 years.] Within the three training tracks, the 20 mentors are grouped into specific themes, such as “aortic disease,” based on their expertise and existing col- laborative relationships. Each track allows trainees to complete a degree, such as a Master in Clinical Re- search, through an established graduate program in the Texas Medical Center. Our program director is Todd Rosengart, MD, Chair of the Michael E. DeBakey Department of Surgery at BCM; co-directors are Scott Le- Maire, MD, Vice Chair for Research, and Barbara Trautner, MD, PhD, Director of Clinical Research. Our lead- ership will be supported by an Executive Steering Committee and five subcommittees: Selection, Curriculum, Individual Development, Program Evaluation, and Faculty Evaluation. The Executive Steering Committee will also receive input from an External Advisory Committee composed of three surgeons who have all directed T32 training programs. [Our highly competitive applicant pool includes 2,587 MD or combined degree appli- cants to our general surgery residency research track and 152 PhD postdoctoral research applicants to our mentors' departments at BCM, Rice University, and the University of Houston (numbers from 2017).] In order to ensure diversity among our trainees, we have enlisted the support of the BCM Office of Institutional Diversity and Inclusion to help during residency interview days and to participate in our Selection Committee. Taken to- gether, we believe these qualifications provide an ideal opportunity for our program to enhance the pool of highly qualified MDs and PhDs contributing to the high-impact arena of research in cardiovascular surgery.