Authentic Bioinformatics in the Classroom (ABC) Project

项目摘要/摘要 迫切需要增加受过生物信息学培训的科学家的数量和多样性 加入生物医学和临床工作队伍。生物信息学被认为是一种职业选择 对于来自代表不足群体的学生来说，在高中培养生物信息学意识是至关重要的。 生物信息学的一个优点是它可以集成到现有的生物内容中，并可以增强 在典型的高中生物课程中生物主题之间的联系。地道的 教室里的生物信息学(ABC)项目利用生物信息学的力量将背景带到 生物学和综合生物信息学在高中生物课上的应用。通过发展生物信息学 针对高中生的以发现和研究为中心的调查(作为全校的单元 年)，生物信息学和科学研究成为生物学的自然组成部分。在这里，以证据为基础 高中生物信息学课程教材将与High 学校生物教师，促进对生物科学的掌握，同时激发兴趣和意识 在来自代表性不足的背景的高中生中进行生物信息学的研究-因此，使他们能够 从事生物医学和临床研究事业，包括生物信息学。为教师做好准备 开发生物信息学课程教材，他们将参加以生物信息学为研究导向的课程 在实验室中，他们将学习完善生物信息学草稿所需的生物信息学概念和技能 课程(由项目组开发并经外部咨询委员会批准)，以便它能够 在他们的高中课堂上得到真正的实施。课程设置将会取得成功 项目团队有丰富经验的建模教学实践。课程设置将 制定NGSS实践，并与几个NGSS主题和交叉概念保持一致，同时参与 学生通过基础生物信息学、数据科学和研究。为了传播课程，该项目 将为高中教师提供专业发展工作坊，以发展教师的 生物信息学知识和技能，通过体验式学习将其纳入课程 机遇，并提供实践和反思的机会。教师将通过以下途径获得支持 他们通过提供来自项目团队的结构化支持来实施课程，准备 本科生(生物信息学大使(BA))、地区课程支持专家、AS 以及一个发展中的教师学习社区。BA还将充当近乎同行的导师和角色 基于对成功助学模式的改编在教师课堂上的模式。

PROJECT SUMMARY/ABSTRACT There is an urgent need to increase the numbers and diversity of bioinformatics-trained scientists joining the biomedical and clinical workforce. For bioinformatics to be considered a career choice by students from underrepresented groups, it is critical to develop awareness of bioinformatics in high school. A strength of bioinformatics is that it can be integrated into existing biological content and can strengthen connections between biological topics in a typical high school biology curriculum. The Authentic Bioinformatics in the Classroom (ABC) Project utilizes the power of bioinformatics to bring context to biology and integrate bioinformatics in high school biology classes. By developing bioinformatics discovery and research-centered investigations for high school students (as modules throughout the school year), bioinformatics and scientific research become a natural part of biology. Here, evidence-based bioinformatics curricular materials for high school biology will be developed in collaboration with high school biology teachers, to promote mastery of biological sciences while stimulating interest and awareness of bioinformatics among high school students from underrepresented backgrounds - thus, enabling them to pursue biomedical and clinical research careers including bioinformatics. To prepare teachers for developing bioinformatics curricular materials, they will participate in a research-oriented bioinformatics lab where they will learn the bioinformatics concepts and skills necessary to refine a bioinformatics draft curriculum (developed by the project team and approved by an External Advisory Committee) so that it can be authentically implemented in their high school classrooms. The curriculum will follow successful Modeling Instruction practices for which the project team has extensive experience. The curriculum will develop NGSS practices and be aligned to several NGSS topics and cross-cutting concepts, while engaging students through basic bioinformatics, data science, and research. To disseminate the curriculum, the project will provide professional development workshops for high school teachers to develop teachers’ bioinformatics knowledge and skills, engage them in the curriculum through experiential learning opportunities, and provide opportunities for practice and reflection. Teachers will be supported through their implementation of the curriculum by providing structured support from the project team, prepared undergraduate students (Bioinformatics Ambassadors (BAs)), district curriculum support specialists, as well as a developing teacher learning community. The BAs will also serve as near-peer mentors and role models in the teachers’ classrooms based on an adaption of the successful Learning Assistant model.