SWG1: HIV/TB Scientific Working Group

SWG1：艾滋病毒/结核病科学工作组

• 批准号: 10454400
• 负责人: Karen R Jacobson
• 金额: $ 5.09万
• 依托单位: MIRIAM HOSPITAL
• 依托单位国家: 美国
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-09-01 至 2023-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10454400
• 关键词: AIDS/HIV problem; Acquired Immunodeficiency Syndrome; Address; Area; Bacteriology; Basic Science; Behavioral; Biological; Boston; Brazil; Clinical; Collaborations; Communities; Data Sources; Development; Diagnosis; Disease; Disease Progression; Elements; Epidemic; Epidemiologist; Fertilization; Fostering; Foundations; Funding; Funding Mechanisms; Goals; HIV; HIV/TB; Imprisonment; India; Institution; International; Investigation; Joints; Kenya; Laboratory Scientists; Longevity; Natural History; Opportunistic Infections; Organism; Outcome; Output; Pathogenesis; Persons; Population; Prevention; Productivity; Research; Research Personnel; Research Proposals; Risk Factors; Russia; Scientist; Site; South Africa; Structure; Substance abuse problem; Translational Research; Tuberculosis; Uganda; Ukraine; United States National Institutes of Health; Work; base; career; improved; innovation; interest; meetings; recruit; tuberculosis diagnostics; virology; working group

Project Summary/Abstract The Providence/Boston (P/B) CFAR's HIV-TB Scientific Working Group (SWG) was established in January 2017, and has built on the complementary scientific expertise of the Brown/Lifespan and BUMC HIV and tuberculosis (TB) research groups, and their domestic and international sites, in order to understand the bidirectional effects of HIV and TB and their respective global epidemics. Currently, research on TB and HIV/TB accounts for a major component of the funded research base (FRB) of the P/B CFAR. There are unique opportunities for the P/B CFAR HIV-TB SWG to develop innovative research in three areas: first, to refocus research on TB to incorporate HIV/TB, addressing issues pertaining to the natural history of HIV and its pathogenesis; second, to introduce biologic components to research that is at this point primarily clinical and/or behavioral; and third, to attract junior and senior researchers to the field. The P/B CFAR has committed to take advantage of these opportunities by creating this HIV-TB SWG. The SWG will bring together investigators currently working on HIV/TB issues with those not currently involved in this research to share ideas and identify potential sub-studies within their currently funded projects, as well as potential new projects. This will be done via bi-monthly lunch meetings, alternating between Brown and BU, annual CFAR sponsored TB meetings, and the SWG Executive Committee will meet semiannually to review participation in these activities and assess whether they are leading to the desired outcomes and outputs. In addition, the SWG will add to the productivity of the other P/B CFAR Cores by applying their expertise to addressing the SWG Specific Aims. Thus, the SWG will add value both by facilitating the development of new and innovative projects as well as by maximizing the productivity of the CFAR Cores.

项目概要/摘要 普罗维登斯/波士顿 (P/B) CFAR 的 HIV-TB 科学工作组 (SWG) 成立于 2017 年 1 月，建立在 Brown/Lifespan 和 BUMC HIV 互补的科学专业知识的基础上 和结核病 (TB) 研究小组及其国内和国际站点，以便了解 艾滋病毒和结核病及其各自的全球流行病的双向影响。目前，结核病和艾滋病毒/结核病的研究 占 P/B CFAR 资助研究基础 (FRB) 的主要组成部分。有独特的 P/B CFAR HIV-TB SWG 在三个领域开展创新研究的机会：第一，重新聚焦 结核病研究纳入艾滋病毒/结核病，解决与艾滋病毒自然史及其相关问题 发病;其次，将生物成分引入目前主要是临床和/或 行为；第三，吸引初级和高级研究人员进入该领域。 P/B CFAR 已承诺采取 通过创建此 HIV-TB SWG 来利用这些机会。 SWG 将汇集目前正在研究艾滋病毒/结核病问题的研究人员以及目前尚未从事艾滋病毒/结核病问题研究的研究人员 参与这项研究以分享想法并确定其当前资助的项目中潜在的子研究， 以及潜在的新项目。这将通过每两个月一次的午餐会议来完成，轮流在布朗大学和布朗大学之间进行。 和 BU、CFAR 主办的年度 TB 会议以及 SWG 执行委员会将每半年举行一次会议，以 审查这些活动的参与情况并评估它们是否带来了预期的成果和产出。 此外，SWG 将通过应用其专业知识来提高其他 P/B CFAR 核心的生产力 解决 SWG 的具体目标。因此，SWG 将通过促进新产品的开发来增加价值。 和创新项目以及最大限度地提高 CFAR 核心的生产力。