Developing Mixed Microbial Populations for Industrial Sidestream Conversion into Textile Dyes and Wider Bio-Products

开发混合微生物群，将工业侧流转化为纺织染料和更广泛的生物产品

• 批准号: 10078639
• 金额: $ 27.29万
• 依托单位: EVOLUTOR LIMITED
• 依托单位国家: 英国
• 项目类别: Collaborative R&D
• 财政年份: 2023
• 资助国家: 英国
• 起止时间: 2023 至 无数据
• 项目状态: 未结题
• 来源: https://gtr.ukri.org/projects?ref=10078639
• 关键词: Developing; Mixed; Microbial; Populations; Industrial

Biomanufacturing using yeast/bacteria and precision fermentation processes is a powerful approach that can displace manufacturing processes that are currently extremely polluting and destructive such as fossil fuel extraction, non-degradable plastic production and intensive animal agriculture. But these harmful industries have decades of infrastructure, economies-of-scale and subsidisation behind them, making the commercial optimisation of biomanufacturing processes to achieve price parity on existing markets a huge challenge for biomanufacturers across all sectors.One way that commercial viability can be achieved is through using cheaper raw materials to feed into precision fermentation processes. Currently, the majority of biomanufacturers use virgin sugars as their feedstocks. These can make up almost 50% of overall biomanufacturing cost, and they also create competition with other markets where these sugars could arguably be better used, for example going directly into existing food manufacturing chains. In this project, Evolutor will use its proprietary microbe optimisation technology platform to develop entirely new microbial systems that can effectively utilise industrial side streams as fermentation feedstocks better than any existing microbial solutions.Side streams are challenging to capture as biomanufacturing feedstocks as they are generally complex, impure and inconsistent, making reliable fermentation difficult. But over 500M tonnes of waste goes to landfill or is incinerated every year (an estimated economic loss of $720B). With Evolutor's new microbe developments, we will unlock side stream valorisation for biomanufacturing on a global scale, pushing our economies closer to a much needed Bio-Industrial Revolution.To demonstrate the power of our new microbes in the first instance, we are partnering with Faber Futures. Faber are developing their "Project Coelicolor" to produce bacterial textile dyes and decentralise the production of high-quality, sustainable garments. By allowing them to use currently wasted or under-valorised side streams as raw materials for this dye production, this project will push Faber Futures' fabrics to market in late 2023 and fulfil their mission of building textile biomanufacturing supply chains that are entirely **ethical, equitable and sustainable** from end-to-end.

使用酵母/细菌和精密发酵工艺的生物制造是一种强大的方法，可以取代目前污染和破坏性极强的制造工艺，如化石燃料提取，不可降解塑料生产和集约化畜牧业。但是，这些有害的行业背后有数十年的基础设施、规模经济和补贴，使得生物制造过程的商业优化以实现现有市场的价格平价对所有行业的生物制造商来说都是一个巨大的挑战。实现商业可行性的一种方法是通过使用更便宜的原材料来进行精确的发酵过程。目前，大多数生物制造商使用初榨糖作为其原料。这些糖可以占整个生物制造成本的近50%，并且它们还与其他市场形成竞争，这些市场可以更好地使用这些糖，例如直接进入现有的食品制造链。在该项目中，Evolutor将利用其专有的微生物优化技术平台开发全新的微生物系统，该系统可以有效地利用工业侧流作为发酵原料，优于任何现有的微生物解决方案。侧流通常复杂，不纯且不一致，难以捕获作为生物制造原料，因此难以进行可靠的发酵。但每年有超过5亿吨的垃圾被填埋或焚烧（估计经济损失为7.2亿美元）。随着Evolutor新微生物的开发，我们将在全球范围内为生物制造业解锁侧流价值，推动我们的经济更接近急需的生物工业革命。为了首先展示我们新微生物的力量，我们与辉柏期货合作。Faber正在开发他们的“Coelicolor项目”，以生产细菌纺织染料，并分散生产高品质，可持续的服装。通过允许他们使用目前被浪费或价值不高的支流作为染料生产的原材料，该项目将在2023年底将Faber Futures的面料推向市场，并履行其建立纺织生物制造供应链的使命，该供应链从端到端完全符合道德，公平和可持续发展。