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ASD3MAP: Amorphous Solid Dispersion Digital Design and Manufacturing Platform for rapid and resource-efficient development of bioavailable medicines

ASD3MAP: Amorphous Solid Dispersion Digital Design and Manufacturing Platform for rapid and resource-efficient development of bioavailable medicines
ASD3MAP:非晶固体分散体数字设计和制造平台,用于快速、资源高效地开发生物可利用药物
批准号:
10078996
负责人:
金额:
$45.52万
依托单位:
依托单位国家:
英国
项目类别:
Collaborative R&D
财政年份:
2023
资助国家:
英国
项目状态:
未结题
起止时间:
2023 至 --

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英文摘要
_**ASD3MAP: Amorphous Solid Dispersion Digital Design and Manufacturing Platform for rapid and resource-efficient development of bioavailable medicines.**_MESOX Ltd (Lead), in collaboration with Aston University (Partner), propose an 18-month project focussing on the refinement of the Consortium's molecular dynamics models through the integration of at market material science and simulation tools to deliver an advanced in-silico formulation development platform for amorphous solid dispersions (ASDs). Furthermore, we will integrate the generated modelling data with thermodynamics and novel computational fluid dynamics (CFD) models to predict the impact of cGMP manufacturing scale-up on the formulation.
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