Administrative Core

项目摘要/摘要 托马斯·J·霍普博士，项目总监，已经组建了调查团队，以此为基础 每个项目/核心负责人和合作调查员的才干和专业知识。这支队伍完全有能力解决 该方案的总体目标是通过将重点放在以下几个方面来“揭开艾滋病毒持续和反弹的机制” 利用创新的技术进步以及团队和外部的最新数据和发现 合作者。核心重点将是激发科学协同效应和新知识的发现。 管理核心(核心A)将作为计划的集中资源发挥关键作用， 全面管理、协调和监督本计划，同时促进 3个项目与NHP核心(核心B)之间的互动，以确保该综合计划的 成功地实现了它的目标。行政核心将设在新大学，并将在以下情况下运作 霍普博士作为项目主管(PD)的直接指导。 行政核心将提供必要的、功能互动的基础设施，支持所有项目 以及具有项目管理的科学核心，包括频繁和及时的交流平台、资源 和数据交换，时间表和财政监督，对研究进展的批判性审查，以及与 更广泛的艾滋病毒/艾滋病研究界，以确保PPG科学目标的成功。通过促进高效 以及所有调查人员之间频繁的沟通和迭代互动，无论是初级还是高级， AC将催化PPG进展，使PI能够主动纳入进展并避免 他们的同事在这组高度互动的3个项目中发现了计划外的障碍

PROJECT SUMMARY/ABSTRACT Thomas J. Hope, PhD, Program Director has assembled the investigative team for this proposed PPG based on the talents and expertise of each project/core leader and co-investigator. This team is perfectly posed to address the overall aim of the program to “unravel the mechanisms of HIV persistence and rebound” by focusing on leveraging innovative technical advances as well as the latest data and findings by the team and outside collaborators. The Core main focus will be to stimulate scientific synergism and the discovery of new knowledge. The Administrative Core (Core A) will serve a critical function as a centralized resource to the Program, providing for the overall management, coordination, and supervision of the Program, while facilitating the interactions between the 3 Projects and the NHP Core (Core B), to guarantee this integrated Program’s success in achieving its objective. The Administrative Core will be located at NU and will be operated under the direct guidance of Dr. Hope as Program Director (PD). The administrative core will provide the essential, functionally-interactive infrastructure supporting all projects and scientific cores with program management including frequent and timely communication platforms, resource and data exchange, timeline and fiscal oversight, critical review of research progress, and engagement with the broader HIV/AIDS research community to ensure the success of the PPG scientific goals. By facilitating efficient and frequent communications as well as iterative interactions between all investigators, both junior and senior, the AC will catalyze PPG progress by enabling PIs to proactively incorporate the advances and avoid the unplanned hurdles discovered by their colleagues in this highly interactive set of 3 projects