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Optically tracked freehand swept synthetic aperture ultrasound

光学跟踪徒手扫描合成孔径超声

基本信息

批准号：
10459552
负责人：
Nick Bottenus
金额：
$ 7.22万
依托单位：
UNIVERSITY OF COLORADO
依托单位国家：
美国
项目类别：
财政年份：
2021
资助国家：
美国
起止时间：
2021-08-01 至 2024-05-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10459552
关键词：
Abdomen Acoustics Affect Area Calibration Carcinoma Cardiac Caring Clinical Clinical assessments Data Development Devices Diagnosis Diagnostic Discipline of obstetrics Electronics Freedom Frequencies Future Gold Health Care Costs Healthcare Human Image Imaging Phantoms Kidney Knowledge Lateral Lead Left Length Lesion Liver Measurement Measures Mechanics Methods Morphologic artifacts Motion Nodule Operative Surgical Procedures Optics Patient imaging Patients Performance Phase Physiologic pulse Point-of-Care Systems Positioning Attribute Research Resolution Risk Scanning Shapes Speed System Techniques Technology Testing Time Tissues Transducers Ultrasonography United States Visualization Weight base clinical application clinical translation cost cost effective diagnostic tool diagnostic value ergonomics fetal high resolution imaging imaging modality imaging system improved in vivo liver imaging point of care screening simulation standard measure targeted imaging tool ultrasound

项目摘要

Project Summary Ultrasound imaging is a critical tool for applications such as obstetric, abdominal and cardiac care. As a non- invasive, real-time, and cost-effective method, ultrasound is the preferred tool for many screening and diagnostic tasks used across the United States and around the world. The proliferation of pocket-sized point of care systems has furthered ultrasound's reach into all areas of healthcare. However, image quality is often inadequate for deep targets in difficult-to-image patients. A lack of resolution at depth and significant acoustic clutter (haze or distortion) lead to non-diagnostic results and high rates of recall or referral to other imaging modalities, increasing healthcare costs and putting patients at risk. Resolution directly depends on the size of the transducer, which is limited by ergonomics of the handheld probe and by system complexity (especially in point of care systems). Targets at large tissue depths also require lower imaging frequencies, exacerbating the degradation of resolution. This project builds on the previously demonstrated swept synthetic aperture (SSA) method to better image deep targets. Using precise knowledge of the position and orientation of the ultrasound array as it is quickly swept over a target, an effective array larger than the physical footprint can be constructed to improve lateral resolution by several times. This proposal focuses on the development of a platform for clinical translation of the SSA technique. Technology that enables a freehand sweep is required to apply SSA imaging to a diversity of body shapes and imaging targets in clinical and point of care settings. An optical tracking system will by synchronized with the ultrasound scanner to allow a sonographer to perform a freehand sweep without mechanical constraints. The position and ultrasound data will be combined with sub-wavelength positional accuracy to achieve images with improved resolution. The imaging system will be characterized using imaging phantoms to assess improvements in resolution and detectability of deep targets. Experimental parameters including the maximum sweep speed and extent as well as practical guidance for the sweep trajectory will be determined using this platform. This freehand SSA system will enable future assessment of the clinical impact of improved resolution on diagnostic tasks across several areas of care. It will also serve as a test platform for array- and image-based tracking to make the image improvements afforded by SSA imaging accessible without the cost or complexity of the external tracking hardware.

项目摘要超声成像是产科、腹部和心脏护理等应用的关键工具。作为一个非- 超声是许多筛查和诊断的首选工具，具有侵入性、实时和成本效益高的特点在美国和世界各地使用的任务。袖珍护理点系统的激增进一步推动了超声波在医疗保健各个领域的应用。然而，图像质量通常不足以满足难以成像的患者的深层靶点。深度分辨率不足和明显的声学杂波(雾霾或失真)导致非诊断结果和高召回率或转诊至其他成像方式，增加医疗成本和将患者置于风险之中。分辨率直接取决于换能器的大小，这受到手持探头的人体工程学的限制以及系统复杂性(尤其是在护理点系统中)。大组织深度的靶点也需要更低的成像频率，加剧了分辨率的下降。这个项目建立在以前的基础上展示了扫描合成孔径(SSA)方法，以更好地成像深部目标。使用精确的知识超声阵列的位置和方向，当它被快速扫过一个目标时，有效的阵列更大则可以构建物理足迹以将横向分辨率提高数倍。这项建议的重点是开发一个SSA技术的临床翻译平台。技术要将SSA成像应用于各种体型和成像，需要实现徒手扫描临床和护理点环境中的目标。光学跟踪系统将与超声波同步扫描仪，允许超声诊断员在没有机械约束的情况下进行徒手扫描。这一立场和将超声数据与亚波长定位精度相结合，实现具有改进的图像决议。成像系统将使用成像模体来表征，以评估在深层目标的分辨率和可探测性。实验参数包括最大扫描速度和使用该平台将确定扫描轨迹的范围和实际制导。这是一幅写意画 SSA系统将使未来能够评估提高分辨率对诊断任务的临床影响在几个护理领域。它还将作为基于阵列和图像的跟踪的测试平台，以 SSA映像提供的图像改进无需外部成本或复杂性即可访问追踪硬件。