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Administrative Core

行政核心

基本信息

批准号：
10461082
负责人：
DAVID A WOLK
金额：
$ 48.98万
依托单位：
UNIVERSITY OF PENNSYLVANIA
依托单位国家：
美国
项目类别：
财政年份：
2021
资助国家：
美国
起止时间：
2021-08-15 至 2026-06-30
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10461082
关键词：
Address Advisory Committees Aging Alzheimer&apos s Disease Alzheimer&apos s disease related dementia Applications Grants Behavioral Research Biocompatible Materials Caring Charge Clinical Clinical Trials Collaborations Community Health Education Data Dementia Development Diagnosis Discipline Disease Early Onset Alzheimer Disease Education Education and Outreach Elderly Enrollment Ensure Epidemiology Event Eye Faculty Family Feedback Fostering Genetic Diseases Goals Grant Growth Human Subject Research Individual Infrastructure Institutes Institution International Leadership Link Mission Monitor Nerve Degeneration Neurodegenerative Disorders Neurosciences Participant Persons Phenotype Positioning Attribute Postdoctoral Fellow Procedures Process Reagent Recommendation Recruitment Activity Reporting Research Research Personnel Research Training Role Science Series Students Teacher Professional Development Techniques United States National Institutes of Health Work brain health career development data dissemination data sharing design disease heterogeneity education research improved innovation lectures meetings member multidisciplinary neuroimaging next generation normal aging novel operation programs repository success

项目摘要

Administrative Core Project Summary The primary goal of the Penn ADRC is to increase research and education on Alzheimer’s disease (AD) and its links to related disorders (ADRD) across the continuum of normal aging to dementia with the goal of identifying the causes of and cures for AD/ADRD. To achieve this goal, the Penn ADRC coordinates research programs, stimulates new research, catalyzes academic research training, provides community education and outreach and fosters the development of novel techniques to individualize diagnosis and treatment for the benefit of all elderly persons and their families. It is the role of the Administrative Core to shepherd and facilitate the activities of the ADRC Cores and to serve as a bridge between the ADRC and national and international efforts in pursuit of these goals. Administrative Core will be involved in a number of different activities that are designed to achieve these broad goals, including fiscal and administrative oversight over the ADRC (Aim 1). The leaders of the ADRC and the ADRC Executive Committee, composed of core leaders and co-leaders, will set priorities and develop plans to achieve ADRC goals. The Administrative Core will choose members of an External Advisory Committee that will be charged with the role of evaluating the progress of the Center and providing recommendations (Aim 2). A variety of forums and opportunities for exchange of ideas and dissemination of data will be supported by the Administrative Core through ADRC sponsored retreats and lecture series (Aim 3). These events will include participation of faculty and trainees, providing an opportunity, particularly for the latter, to present data and receive feedback. Critical to the growth and breadth of AD/ADRC research, a unique Developmental Project program linked to topics at annual retreats will foster transdisciplinary work (Aim 4). The Administrative Core will champion participation of the Penn ADRC in numerous state, national, and international efforts to improve care and treatment of ADRD, as well as provide infrastructure to support the sharing of data and biomaterials (Aim 5). Finally, the core will provide oversight on all NIA and local regulatory and reporting procedures and requirements (Aim 6). Critically, the Administrative Core serves to maintain the “centeredness” of the ADRC by coordinating efforts across the individual cores, by promoting collaborations with other neurodegenerative centers at Penn and beyond, and by promoting activities consistent with our thematic focus around AD heterogeneity. By achieving the above aims, we expect to maintain our highly productive ADRC with the appropriate support to do novel research, to contribute highly and deeply phenotyped individuals to larger data sharing efforts, to grow our diverse and multi-disciplinary faculty by training the next generation of investigators and clinicians, and to educate and empower our region and the nation so as to improve brain health and meet the goals of NAPA.

行政核心项目总结