Clinical Orthopaedic and Musculoskeletal Education and Training Program (COMET)

临床骨科和肌肉骨骼教育和培训计划（COMET）

• 批准号: 10461765
• 负责人: Jeffrey Neil Katz
• 金额: $ 29.33万
• 依托单位: BRIGHAM AND WOMEN'S HOSPITAL
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-07-01 至 2024-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10461765
• 关键词: Clinical; Musculoskeletal; Orthopedics; Training Programs; Training and Education

Musculoskeletal (MSK) and orthopaedic disorders are staggeringly prevalent, disabling, and costly, accounting for ~5% of gross domestic product in the US. The COMET (Clinical Orthopaedic and Musculoskeletal Education and Training) T32 training program is focused on training clinical researchers to address the growing national and global burden of MSK disorders through rigorous clinical research. The COMET program has been highly successful in its first decade; 21 of its 25 graduates have remained in academic positions, with 8 receiving career development awards (5 K-level awards and 3 Rheumatology Research Foundation career development awards), and 5 R-level grants (3 R01s and 2 R21s). These 25 graduates have published 112 peer-reviewed papers based on their T32-funded work. Nearly 70% of current and former trainees are women and 3 belong to underrepresented minority groups. In this competitive renewal resubmission, we propose a programmatic focus on 6 research training concentrations that represent pressing research needs and draw on the strengths of the faculty: exercise and physical activity; orthopedic surgical outcomes; innovative non-pharmacologic trials; value-based care; work and MSK disorders; and MSK health in resource-limited settings. Trainees address these and related research themes in relation to a broad range of MSK and orthopaedic disorders, including osteoarthritis, osteoporosis, regional disorders (spine, knee, shoulder, upper extremity, foot/ankle), orthopaedic trauma, joint and soft tissue problems, nerve entrapments, chronic pain, and related conditions. Through their COMET training, young investigators acquire critical skills in biostatistics and epidemiology along with a range of other disciplines based on their career interests (e.g. behavioral science, economic analysis, clinical trials). Trainees without prior formal didactic training in these methodologies obtain a master's degree in the Clinical Effectiveness Program at the Harvard T.H. Chan School of Public Health. Drs. Jeffrey Katz and Elena Losina direct the COMET program and are supported by a highly experienced, productive, and collaborative group of faculty mentors from throughout the Harvard medical and public health communities. This application requests funding for two predoctoral and three postdoctoral training positions per year. This renewal resubmission application builds upon a foundation of success over the first decade of the program and is driven by the overarching goal of facilitating research to improve the quality of life of persons with debilitating MSK disorders.

肌肉骨骼（MSK）和骨科疾病非常普遍，残疾和昂贵，会计 在美国约有5％的国内生产总值。彗星（临床骨科和肌肉骨骼 教育和培训）T32培训计划的重点是培训临床研究人员，以解决 通过严格的临床研究，MSK疾病的国家和全球负担增加。彗星程序 在头十年中一直非常成功；它的25名毕业生中有21位仍然处于学术职位， 8获得职业发展奖（5个K级奖项和3个风湿病研究基金会职业生涯 开发奖）和5个R级补助金（3 R01和2 R21）。这25位毕业生已出版了112 根据他们的T32资助的作品进行了同行评审的论文。近70％的现任和以前的学员是女性 3属于代表性不足的少数群体。 在这种竞争性更新重新提交中，我们建议对6个研究培训进行计划重点 代表紧迫研究需求并利用教师的优势的集中度：锻炼和 体育锻炼；骨科手术结果；创新的非药物试验；基于价值的护理；工作 和MSK疾病；和MSK Health在资源有限的设置中。受训者解决这些研究和相关研究 与广泛的MSK和骨科疾病有关的主题，包括骨关节炎，骨质疏松症， 区域疾病（脊柱，膝盖，肩膀，上肢，脚/脚踝），骨科创伤，关节和软组织 问题，神经诱捕，慢性疼痛和相关状况。通过他们的彗星训练，年轻 研究人员获得生物统计学和流行病学方面的关键技能以及一系列其他学科 根据他们的职业兴趣（例如行为科学，经济分析，临床试验）。没有学员 这些方法中的事先正式教学培训获得了临床有效性的硕士学位 哈佛大学的计划陈公共卫生学院。博士。杰弗里·卡茨（Jeffrey Katz）和埃琳娜·洛西纳（Elena Losina）指导 彗星计划，并得到经验丰富，富有成效和协作的教师的支持 整个哈佛医学和公共卫生社区的指导者。此申请要求资金 对于每年的两个毒品和三个博士后培训职位。此更新重新提交申请 基于该计划的前十年的成功基础，并由总体目标驱动 促进研究以改善MSK疾病的人的生活质量。