Stanford University Regional Coordinating Stroke Center for the NIH Stroke Trials Network

斯坦福大学 NIH 卒中试验网络区域卒中协调中心

• 批准号: 10467057
• 负责人: GREGORY W ALBERS
• 金额: $ 29.09万
• 依托单位: STANFORD UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-08-15 至 2023-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10467057
• 关键词: American Heart Association; American Stroke Association; Area; Basic Science; Blood Vessels; Brain Injuries; Caring; Cerebral hemisphere hemorrhage; Cerebrovascular Disorders; Certification; Childhood stroke; Clinical; Clinical Research; Clinical Trials; Clinical Trials Design; Clinical and Translational Science Awards; Collection; Coma; Comprehensive Health Care; Country; Data Set; Development; Diagnosis; Disease; Education; Enrollment; Faculty; Fellowship; Fellowship Program; Funding; Generations; Goals; Grant; Hospitals; Image; Imaging Techniques; Individual; Infrastructure; Intervention; Joints; Laboratories; Laboratory Research; Lead; Magnetic Resonance Imaging; Master of Science; Medical; Mentors; Mission; National Institute of Neurological Disorders and Stroke; Neurologist; Neurology; Neurosurgeon; Nurses; Nursing Faculty; Patients; Probability; Procedures; Prognosis; Protocols documentation; Randomized Controlled Trials; Research; Research Personnel; Research Project Grants; Running; Scientist; Site; Specialist; Stroke; Stroke prevention; Techniques; Testing; Training; Translational Research; United States; United States National Institutes of Health; Universities; X-Ray Computed Tomography; acute stroke; base; brain tissue; clinical center; clinical trial implementation; data management; design; epidemiology study; experience; imaging approach; innovation; medical schools; member; multidisciplinary; neuroimaging; neurological rehabilitation; neurosurgery; novel strategies; participant enrollment; patient population; programs; stem cell therapy; stroke recovery; stroke therapy; stroke trials; success

The Stanford Stroke Center, one of the first comprehensive multidisciplinary centers of its kind, was established in 1992 to develop new approaches to diagnose and treat stroke. The mission of the Stroke Center is to be the best comprehensive organization in the United States focused on stroke diagnosis, treatment, research, and education. In 1992, the Center was established by a team of neurologists, neurosurgeons, neuroradiologists, nurse specialists, basic scientists, and clinical researchers. This multi-disciplinary team has met regularly to continually refine the program for 25 years. In 2012, the Joint Commission and the American Heart Association/American Stroke Association announced that the Stanford Stroke Center was the first hospital in the United States to meet The Joint Commission's standards for Disease-Specific Care Comprehensive Stroke Center Certification. Stanford was chosen to be one of the original StrokeNet Regional Coordinating Centers (RCCs). During the initial grant period, Stanford developed the DEFUSE 3 study, which became the first clinical trial to be funded and executed by StrokeNet. This 40-site trial has been extremely successful; enrollment rates were substantially ahead of projected targets and the trial was stopped early by the DSMB because of a high probability of efficacy in the endovascular group. Stanford's regional network is one of the highest enrollers in StrokeNet studies and Stanford faculty have made major contributions to key StrokeNet committees. The Stanford-RCC will continue to provide high volume enrollment of diverse patient populations into NINDS funded stroke trials. The Stanford RCC will also continue to offer an innovative multidisciplinary fellowship program that provides comprehensive training in clinical trial design, implementation and analysis. In addition, Stanford faculty members will continue to propose new clinical trials for implementation through StrokeNet.

斯坦福大学卒中中心是同类中心中最早的综合性多学科中心之一， 成立于1992年，旨在开发诊断和治疗中风的新方法。中风中心的使命 是成为美国最好的综合性组织，专注于中风的诊断，治疗， 研究和教育。1992年，该中心由一组神经学家，神经外科医生， 神经放射学家、护理专家、基础科学家和临床研究人员。这个跨学科的团队 25年来，定期开会，不断完善该计划。2012年，联合委员会和美国 心脏协会/美国中风协会宣布，斯坦福大学中风中心是第一个 医院在美国，以满足联合委员会的标准，疾病的具体护理 综合中风中心认证。 斯坦福大学被选为最初的中风网络区域协调中心（RCC）之一。期间 在最初的拨款期间，斯坦福大学开发了DEFUSE 3研究，成为第一个获得资助的临床试验 并由中风网执行这项40个地点的试验非常成功;入组率为 大大超过了预期的目标，DSMB提前停止了试验，因为 血管内组的有效性概率。斯坦福大学的区域网络是其中一个最高的招生， StrokeNet研究和斯坦福大学的教师为StrokeNet的主要委员会做出了重大贡献。的 Stanford-RCC将继续为NINDS提供大量不同患者人群的入组 资助的中风试验。斯坦福大学区域合作中心还将继续提供创新的多学科奖学金 该计划提供临床试验设计，实施和分析方面的综合培训。此外，本发明还提供了一种方法， 斯坦福大学的教职员工将继续提出新的临床试验，通过中风网络实施。