Core 1: Administrative Core

核心1：项目总结 管理核心(核心1)对耶鲁大学孢子皮肤癌(YSPORE)的成功至关重要。这个 核心的主要目的是支持和促进皮肤癌的跨学科研究努力，并确定 新的挑战和机遇不断涌现。行政核心是中心协调 YSPORE调查人员的重点，负责监测所有项目和核心的进展情况 转换/临床终点。这些服务包括提供(A)财政管理、(B)文书和 组织支助，(C)内部和外部审查机制，(D)支持加强科学 项目/核心领导之间的互动和协作，(E)监测项目和核心的机制 (F)协调外联工作；(G)建立扩大皮肤癌研究的机制 除了孢子的活动，耶鲁大学内外都是如此。CORE 1还将负责 确保耶鲁大学孢子在皮肤癌方面的活动与耶鲁癌症中心的活动充分结合， 目标是避免工作重叠和重复，同时最大限度地发挥协同作用和利用资源。任何 孢子调查员之间可能出现的冲突将由核心1主任处理，并提供投入 执行委员会、外部和内部咨询委员会以及Charles Fuchs医学博士(如果需要)。 核心1将与生物信息学和生物统计核心(核心3)密切合作，以确保整合数据 由孢子计划产生的数据传输到耶鲁癌症中心，反之亦然，并监督共享 其他皮肤癌/黑色素瘤孢子部位的数据，如果合适的话，还有耶鲁大学肺部的孢子 癌症。将与孢子研究人员举行正在进行的联合科学研究会议，由 核心1，确保思想的双向流动和资源的共享。参与该项目的调查人员将 还参加由核心1与行政部门合作举办的孢子间年度研讨会 其他站点的核心。YSPORE在康涅狄格州纽黑文主办了2017年孢子间研讨会。核心将是 导演是Marcus Bosenberg博士和Harriet Kluger博士，联席导演是Mario Sznol博士。计划监督 核心1将在执行委员会的投入下完成，并为科学和行政投入 将向内部和外部咨询委员会寻求职能。与内部和外部的年度会议 外部咨询委员会将由核心1组织。核心还将组织正在进行的研究研讨会， 外部调查人员的谈话，以及患者和社区的外展。 好了！

CORE 1: PROJECT SUMMARY The Administrative Core (Core 1) is critical to the success of the Yale SPORE in Skin Cancer (YSPORE). The primary purpose of the Core is to support and facilitate transdisciplinary research efforts in skin cancer and identify new challenges and opportunities as they emerge. The Administrative Core serves as the central coordination point for YSPORE investigators, with responsibility for monitoring the progress of all projects and cores toward a translational/clinical endpoint. These services include provision of (a) fiscal management, (b) clerical and organizational support, (c) mechanisms for internal and external review, (d) support for enhancement of scientific interactions and collaborations among the Project/Core leaders, (e) mechanisms to monitor projects and cores for scientific progress, (f) coordination of outreach efforts, and (g) mechanisms to expand research in skin cancer beyond the activities of the SPORE, both within Yale and outside of Yale. Core 1 will also be responsible for ensuring full integration of activities of the Yale SPORE in Skin Cancer with those of Yale Cancer Center, with the goal of avoiding overlap and duplication of efforts while maximizing synergy and use of resources. Any conflicts that might arise between SPORE investigators will be addressed by the Core 1 Directors, with input from the Executive Committee and the External and Internal Advisory Boards and Charles Fuchs, MD if needed. Core 1 will work closely with the Bioinformatics and Biostatistics Core (Core 3) to ensure the integration of data generated by the SPORE program into that of Yale Cancer Center and vice versa, and to oversee sharing of data with other skin cancer/melanoma SPORE sites, and when appropriate, with the Yale SPORE in Lung Cancer. Joint scientific research in progress meetings will be held with the SPORE researchers, organized by Core 1, to ensure bi-directional flow of ideas and sharing of resources. Investigators involved in this program will also participate in the annual inter-SPORE workshops, organized by Core 1 in collaboration with Administrative Cores at other sites. YSPORE hosted the 2017 inter-SPORE workshop in New Haven, CT. The Core will be directed by Drs. Marcus Bosenberg and Harriet Kluger and the Co-Director is Dr. Mario Sznol. Program oversight by Core 1 will be done with input from the Executive Committee, and input for scientific and administrative functions will be sought from the Internal and External Advisory Boards. Annual meetings with the Internal and External Advisory Boards will be organized by Core 1. The Core will also organize research in progress seminars, talks by outside investigators, and patient and community outreach. !