University of Utah Center of Excellence in ELSI research (UCEER)

项目总结 此申请是为犹他州ELSI研究卓越中心续签资金 (UCEER)。我们的中心在2014-2016年间获得了P20赠款的资助，并在 2016-2020年RM1赠款。UCEER主要关注以人口为基础的ELSI问题 基因检测和筛查。在当前的供资周期中，欧洲能源、环境和经济研究中心高度重视 关于新生儿筛查、产前筛查和携带者筛查。对于此次续签，我们建议 将这一重点扩大到也涉及遗传残疾问题，包括成本效益问题 家庭和社区内的治疗、适应和支持以及法律/政策 问题。此外，我们建议处理以人口为本的文物测试所引起的问题。 由直接面向消费者的基因检测公司。我们建议保持一套强有力的努力 让来自广泛学科的教职员工和从本科生到 博士后水平。UCEER已获得NHGRI颁发的R25奖金，与我们的RM1资金有关， 这为认同残疾的本科生和研究生提供支持。UCEER有 制定了高效的管理结构和流程以及强大的员工团队，以 支持我们的研究和教育项目。

PROJECT SUMMARY This application is for renewal of funding for the Utah Center of Excellence in ELSI Research (UCEER). Our Center has received funding under a P20 grant from 2014 – 2016 and under an RM1 grant from 2016 – 2020. UCEER is primarily focused on ELSI issues in population-based genetic testing and screening. For the current funding cycle, UCEER has had a strong emphasis on newborn screening, prenatal screening and carrier screening. For this renewal, we propose extending this focus to also address issues with genetic disabilities, including cost- effectiveness of treatments, adaptation and support within families and the community, and legal/policy issues. In addition, we propose to address issues arising from population-based heritage testing by direct to consumer genetic testing companies. We propose to maintain a robust set of efforts to involve faculty from a broad range of disciplines and students from the undergraduate to post-doc levels. UCEER has received a R25 award from NHGRI, linked to our RM1 funding, that supports undergraduate and graduate students who identify with a disability. UCEER has developed an efficient administrative structure and processes and a strong group of staff to support our research and educational programs.