课题基金 / 基金详情

Research Education Component

Research Education Component
研究教育部分
批准号:
10475196
负责人:
DEBOMOY K LAHIRI
金额:
$12.81万
依托单位国家:
美国
项目类别:
财政年份:
2021
资助国家:
美国
项目状态:
未结题
起止时间:
2021-09-01 至 2026-06-30

项目摘要

项目成果

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中文摘要
翻译
项目摘要-研究教育部分(REC) 阿尔茨海默病(Alzheimer's disease,AD)的研究因其实质性的创新而一直处于神经科学的前沿 分子生物学、遗传学、神经病理学和成像技术。然而,一个关键的需要仍然是 存在的专业人员与专门培训,使基础和临床神经科学的AD进入下一个 一代REC的目标是培养新的研究人员,他们经过专门培训,能够发现创新方法, 提高对AD和其他痴呆症的认识、诊断和治疗。REC的意义在于促进 IADRC的使命是促进教育、信息和培训;协调各实验室;以及 评估研究教育的成功。REC的目标是与其他核心的概念协同, 包括生物标志物,神经影像学,痴呆症临床核心,神经病理学,遗传学和数据科学(或 简单地说BiNDiNGS),以学生/受训人员在培训、职业发展和传播方面提供领导 不同核心的活动,从而通过指导新的科学家来扩展当前和未来的研究, 在这一跨学科领域做好充分准备,并准备作出重要贡献。REC将扩大 通过培养来自不同背景的新科学家,包括代表性不足的科学家, 少数民族(URM),在这一跨学科领域做好了充分准备,并准备好使重要的 捐款.促进地方,区域和国家早期职业调查人员的合作将显着 推进AD研究领域。 REC的五个具体目标是: 1)在IADRC内为研究教育提供组织基础设施 2)灌输大脑健康和痴呆症的综合基础知识 3)招聘,留住,并协助学生和教师在多个职业水平 4)确定具体的衡量标准,以评估区域环境中心在为学员提供服务方面的进展 5)促进IADRC核心之间在研究教育方面的跨学科互动和合作
英文摘要
Project Summary – Research Education Component (REC) Alzheimer’s disease (AD) research has been at the forefront of neuroscience due to its substantive innovations in molecular biology, genetics, neuropathology, and imaging technologies. Nevertheless, a critical need still exists for professionals with specialized training to bring basic and clinical neuroscience of AD into the next generation. REC’s goal is to develop new researchers specifically trained to discover innovative approaches to improve understanding, diagnosis, and treatment of AD and other dementias. REC’s significance is fostering the mission of the IADRC to stimulate education, information, and training; coordinate across laboratories; and evaluate success in research education. REC’s objective is to synergize with the concepts of other cores, including Biomarkers, Neuroimaging, Dementia Clinical Core, Neuropathology, Genetics and Data Science (or simply BiNDiNGS) to students/trainees to provide leadership in training, career development, and dissemination activities of the different Cores, thereby expanding current and future research by mentoring new scientists to be well-prepared in this transdisciplinary area and poised to make important contributions. The REC will expand current and future research by fostering new scientists from diverse backgrounds, including underrepresented minorities (URMs), well-prepared in this transdisciplinary area, and who are poised to make important contributions. Fostering local, regional, and national collaborations of early career investigators will significantly advance the field of AD research. REC’s five Specific Aims are: 1) Provide organizational infrastructure within IADRC for research education 2) Instill integrated fundamental knowledge of brain health and dementing illnesses 3) Recruit, retain, and assist students and faculty at multiple career levels 4) Define specific metrics to assess the progress of REC in its service of mentees 5) Foster cross-disciplinary interactions and collaborations in research education among IADRC cores
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会议论文
Alzheimer's disease-linked microRNA Exploration of UTR Polymorphisms (AdmiRE-UP)
Brain protein alteration by vascular overexpressed miRNA (BravomiR)
Research Education Component
Research Education Component
国内基金
海外基金
新型F-18标记香豆素衍生物PET探针的研制及靶向Alzheimer's Disease 斑块显像研究
  • 批准号:
    81000622
  • 项目类别:
    青年科学基金项目
  • 资助金额:
    20.0万元
  • 批准年份:
    2010
  • 负责人:
    梁胜
  • 依托单位:
阿尔茨海默病(Alzheimer's disease,AD)动物模型构建的分子机理研究
  • 批准号:
    31060293
  • 项目类别:
    地区科学基金项目
  • 资助金额:
    26.0万元
  • 批准年份:
    2010
  • 负责人:
    郭亚芬
  • 依托单位:
跨膜转运蛋白21(TMP21)对引起阿尔茨海默病(Alzheimer'S Disease)的γ分泌酶的作用研究