TRANSFORM: Translational Research that Adapts New Science FOR Maltreatment prevention

转变：采用新科学预防虐待的转化研究

• 批准号: 10475233
• 负责人: DANTE CICCHETTI CICCHETTI
• 金额: $ 156.59万
• 依托单位: UNIVERSITY OF ROCHESTER
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-09-13 至 2023-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10475233
• 关键词: Address; Adolescent; Adult; Applied Research; Basic Science; Child; Child Abuse and Neglect; Child Mental Health; Child Welfare; Childhood; Communities; Consensus; Development; Discipline; Domestic abuse; Environment; Evidence based intervention; Evidence based program; Evidence based treatment; Experimental Designs; Exposure to; Family; Formulation; Fostering; Foundations; Genetic; Goals; Government; Human; Individual; Infrastructure; Injury; Institutes; Interdisciplinary Study; International; Intervention; Investigation; Laboratories; Lawyers; Leadership; Legal; Life; Maps; Measures; Mediator of activation protein; Mental Health; Methodology; Methods; Minnesota; Modeling; Mothers; National Institute of Child Health and Human Development; Neurosciences; Outcome; Postdoctoral Fellow; Postpartum Period; Prevention; Prevention Research; Principal Investigator; Provider; Psychopathology; Quality Control; Randomized Controlled Trials; Reporting; Research; Research Methodology; Research Personnel; Research Project Grants; Resource Sharing; Resources; Science; Scientist; Sexual abuse; Societies; Solid; System; Testing; Training; Training and Education; Translating; Translational Research; Trauma; Underrepresented Minority; Universities; Work; abuse neglect; analytical method; career; career development; clinical practice; community engagement; community violence; court; emotional abuse; evidence base; experience; graduate student; high risk; high risk population; innovation; maltreatment; multidisciplinary; next generation; outreach; physical abuse; physical conditioning; preference; prenatal; prevent; preventive intervention; programs; prospective; research data dissemination; service providers; therapy design; translational approach

ABSTRACT - OVERALL CORE Each year millions of young children and adolescents in the U.S. are reported to Child Protective agencies for maltreatment (neglect, physical, sexual, or emotional abuse), and experience additional forms of trauma such as exposure to domestic abuse, community violence, life-threatening illness or injury, or sudden loss. A diverse multidisciplinary team of investigators from the Universities of Rochester and Minnesota will partner with the NICHD to create the TRANSFORM Center (Translational Research that Adapts New Science FOR Maltreatment Prevention) to prevent child maltreatment and to address its sequelae. The unique combined capacity of this multi-investigator Center, i.e., the expertise, infrastructure support, human/fiscal resources, and research/intervention strategies would not be feasible for a single investigator working alone in one laboratory. Building on current state-of-the-science research methodologies and clinical practices that address the personal and societal burden associated with child abuse and neglect, TRANSFORM will leverage theoretically-grounded evidence-based research and preventive interventions to optimize outcomes in children. In doing so, the Center will apply the most advanced concepts and methods derived from child maltreatment research, and leverage numerous longstanding relationships within the child welfare community to make its impact. TRANSFORM will use a multidisciplinary translational approach embedded in a developmental psychopathology framework that builds upon discoveries in genetics, neuroscience, prevention and intervention science, child welfare, and court systems to develop an innovative national resource for diverse disciplines and professional arenas. To achieve its objectives, TRANSFORM will utilize two Research Projects and two mutually-informative and integrated Cores: a Community Engagement Core, and an Administrative Core. This `team science' model brings together professionals with different backgrounds including basic and applied scientists who provide the theoretical grounding for project hypotheses, program developers who are the architects of evidence-based programs, research methodologists who advise on the appropriate experimental designs for testing the models, including the constructs and measures that will map onto the mediators and moderators, the analytical methods for evaluating results, attorneys who can translate results into legal and judicial systems, and child-serving professionals and governmental stakeholders who will participate in dissemination activities. TRANSFORM will be led by Drs. Sheree Toth and Dante Cicchetti, internationally-recognized leaders in the field of child maltreatment, whose collaborative work spans almost four decades and provides a solid foundation for conducting groundbreaking longitudinal and prevention research that will contribute to widespread engagement across multiple child-serving systems.

抽象-整体核心 每年，美国有数百万儿童和青少年被报告给儿童保护机构 虐待(忽视、身体、性或情感虐待)，并经历其他形式的创伤，如 如遭受家庭暴力、社区暴力、危及生命的疾病或伤害，或突然失去生命。一个多样化的 来自罗切斯特大学和明尼苏达大学的多学科调查小组将与 NICHD将创建转化中心(适应新科学的翻译研究 防止虐待儿童(防止虐待)，以防止虐待儿童并解决其后遗症。独一无二的组合 该多名调查员中心的能力，即专业知识、基础设施支持、人力/财政资源和 研究/干预战略对于在一个实验室中单独工作的单一调查员来说是不可行的。 建立在当前最先进的研究方法和临床实践的基础上，解决 与虐待和忽视儿童相关的个人和社会负担，转变将利用 以理论为基础的循证研究和预防干预措施，以优化儿童的结果。 在这样做的过程中，该中心将应用源自虐待儿童的最先进的概念和方法 研究，并利用儿童福利界内的许多长期关系来使其 冲击力。转型将使用嵌入在开发中的多学科翻译方法 精神病理学框架，建立在遗传学、神经科学、预防和 干预科学、儿童福利和法院系统，为不同群体开发创新的国家资源 纪律和专业领域。为了实现其目标，Transform将利用两个研究项目 和两个相互提供信息和集成的核心：社区参与核心和管理 核心。这种‘团队科学’模式将具有不同背景的专业人士聚集在一起，包括基础和 为项目假设提供理论基础的应用科学家、程序开发人员 循证项目的设计者，研究方法学家，他们就适当的 用于测试模型的实验设计，包括将映射到 调解人和主持人，评估结果的分析方法，能够翻译结果的律师 法律和司法系统，以及服务儿童的专业人员和政府利益攸关方，他们将 参与传播活动。Transform将由Sheree Toth博士和Dante Cicchetti博士领导， 国际公认的虐待儿童领域的领导人，他们的合作工作几乎跨越了 四十年，为开展开创性纵向预防工作奠定了坚实的基础 将有助于在多个儿童服务系统中广泛参与的研究。