Pain Management Collaboratory Coordinating Center (PMC3)

项目摘要/摘要 疼痛管理合作实验室协调中心(PMC3)将(1)提供国家领导和 在支持高影响力设计和执行的所有方面的研究方面的技术专长 开展具有成本效益的、大规模、务实的临床试验的示范项目 退伍军人或军人健康中疼痛控制和其他并存疾病的药理学方法 护理系统，以及(2)提供来自这些项目和其他项目的数据、工具、最佳做法和资源 促进退伍军人事务部和国防部卫生系统的研究伙伴关系。PMC3将利用 退伍军人事务部疼痛研究、信息学、多发病和教育(PRIME)创新中心 康涅狄格州医疗保健系统(VACHS)及其在VACHS和耶鲁的合作伙伴，包括VA合作社 研究项目协调中心/临床流行病学研究中心和耶鲁大学研究中心 分析科学和耶鲁医学信息学中心，通过与同事的紧密合作而得到加强 在统一服务大学的康复科学研究和健康科学中心 由国防部和大学合作组成的新型军事治疗设施参与委员会 致力于促进国防部成功进行务实试验的附属研究人员、临床医生和教育工作者 设置。我们将利用我们在疼痛管理、电子健康记录(EHR)、数据系统和 与我们的合作，设计和协调多点实用试验以实现这些目标 弗吉尼亚州、国防部和耶鲁大学的合作伙伴。为了实现这些目标，将处理三个具体的模拟人生目标：目标1： 制定、调整和采用技术政策指南和最佳做法，以便有效地设计和实施 务实试验；目标2：与之合作并提供操作、技术、设计和其他 支持示范项目小组制定、启动和实施研究方案；目标3： 广泛传播NIH-DoD-VA疼痛管理合作实验室认可的政策和最佳实践以及 在军队和退伍军人保健系统中吸取的经验教训。实现这些目标和具体目标 AIMS承诺显著加快循证非药理学方法的整合 在军队和退伍军人医疗保健系统中将疼痛管理纳入常规临床护理符合 来自国家疼痛战略的主要建议。

Project Summary / Abstract The Pain Management Collaboratory Coordinating Center (PMC3) will (1) provide national leadership and technical expertise in all aspects of research supporting the design and execution of high impact Demonstration Projects that conduct cost-effective, large-scale, pragmatic clinical trials on non- pharmacological approaches for pain management and other comorbid conditions in veteran or military health care systems, and (2) make data, tools, best practices, and resources from these and other projects available to facilitate research partnerships in VA and DoD health systems. The PMC3 will leverage the expertise of the Pain Research, Informatics, Multimorbidities and Education (PRIME) Center of Innovation based at the VA Connecticut Healthcare System (VACHS) and its partners at VACHS and Yale, including the VA Cooperative Studies Program Coordinating Center/Clinical Epidemiology Research Center and the Yale Center for Analytical Sciences and Yale Center for Medical Informatics, enhanced by a strong partnership with colleagues at the Uniformed Services University for the Health Sciences Center for Rehabilitation Sciences Research and a novel Military Treatment Facility Engagement Committee comprised of collaborating DoD and university affiliated investigators, clinicians and educators devoted to facilitating successful pragmatic trials in DoD settings. We will use our expertise in pain management, electronic health records (EHR), data systems and the design and coordination of multi-site pragmatic trials to accomplish these objectives in collaboration with our VA, DoD and Yale partners. To achieve these objectives, three specific sims will be addressed: Aim 1: To develop, adapt and adopt technical policy guidelines and best practices for the effective design and conduct of pragmatic trials; Aim 2: To work collaboratively with and provide operational, technical, design and other support to Demonstration Project teams to develop, initiate and implement a research protocol; and Aim 3:To widely disseminate NIH-DoD-VA Pain Management Collaboratory endorsed policies and best practices and lessons learned within military and veteran health care systems. Achievement of these objectives and Specific Aims promise to significantly accelerate the integration of evidence-based non-pharmacological approaches for the management of pain into routine clinical care in military and veteran health care systems consistent with key recommendations from the National Pain Strategy.