Pain Management Collaboratory Coordinating Center (PMC3)

项目总结/摘要 疼痛管理合作实验室协调中心（PMC 3）将（1）提供国家领导， 在支持高影响力的设计和执行的研究的各个方面的技术专长 示范项目，对非结核病患者进行具有成本效益的、大规模的、务实的临床试验。 用于疼痛管理和退伍军人或军事健康中的其他共病状况的药理学方法 护理系统，以及（2）提供来自这些项目和其他项目的数据、工具、最佳实践和资源 促进退伍军人事务部和国防部卫生系统的研究伙伴关系。PMC 3将利用 疼痛研究，信息学，多病和教育（PRIME）创新中心，位于弗吉尼亚州 康涅狄格州医疗保健系统（VACHS）及其在VACHS和耶鲁大学的合作伙伴，包括VA合作社 研究项目协调中心/临床流行病学研究中心和耶鲁大学 分析科学和耶鲁大学医学信息学中心，通过与同事的强有力的合作关系得到加强 在统一服务大学康复科学研究健康科学中心， 由国防部和大学合作组成的新型军事治疗设施参与委员会 致力于促进国防部成功的实用试验的附属调查人员、临床医生和教育工作者 设置.我们将利用我们在疼痛管理、电子健康记录（EHR）、数据系统和 设计和协调多地点的务实试验，以实现这些目标，与我们的合作 退伍军人管理局国防部和耶鲁大学的合作伙伴为了实现这些目标，将解决三个具体的西姆斯：目标1： 制定、调整和采用技术政策准则和最佳做法， 目标2：与合作伙伴合作，提供运营、技术、设计和其他服务， 支持示范项目小组制定、启动和实施研究方案;目标3： 广泛传播NIH-DoD-VA疼痛管理合作实验室认可的政策和最佳实践， 在军队和退伍军人医疗保健系统中吸取的教训。实现这些目标和具体 目的是承诺大大加快整合循证非药理学方法， 将疼痛管理纳入军队和退伍军人医疗保健系统的常规临床护理， 国家疼痛战略的主要建议。

Project Summary / Abstract The Pain Management Collaboratory Coordinating Center (PMC3) will (1) provide national leadership and technical expertise in all aspects of research supporting the design and execution of high impact Demonstration Projects that conduct cost-effective, large-scale, pragmatic clinical trials on non- pharmacological approaches for pain management and other comorbid conditions in veteran or military health care systems, and (2) make data, tools, best practices, and resources from these and other projects available to facilitate research partnerships in VA and DoD health systems. The PMC3 will leverage the expertise of the Pain Research, Informatics, Multimorbidities and Education (PRIME) Center of Innovation based at the VA Connecticut Healthcare System (VACHS) and its partners at VACHS and Yale, including the VA Cooperative Studies Program Coordinating Center/Clinical Epidemiology Research Center and the Yale Center for Analytical Sciences and Yale Center for Medical Informatics, enhanced by a strong partnership with colleagues at the Uniformed Services University for the Health Sciences Center for Rehabilitation Sciences Research and a novel Military Treatment Facility Engagement Committee comprised of collaborating DoD and university affiliated investigators, clinicians and educators devoted to facilitating successful pragmatic trials in DoD settings. We will use our expertise in pain management, electronic health records (EHR), data systems and the design and coordination of multi-site pragmatic trials to accomplish these objectives in collaboration with our VA, DoD and Yale partners. To achieve these objectives, three specific sims will be addressed: Aim 1: To develop, adapt and adopt technical policy guidelines and best practices for the effective design and conduct of pragmatic trials; Aim 2: To work collaboratively with and provide operational, technical, design and other support to Demonstration Project teams to develop, initiate and implement a research protocol; and Aim 3:To widely disseminate NIH-DoD-VA Pain Management Collaboratory endorsed policies and best practices and lessons learned within military and veteran health care systems. Achievement of these objectives and Specific Aims promise to significantly accelerate the integration of evidence-based non-pharmacological approaches for the management of pain into routine clinical care in military and veteran health care systems consistent with key recommendations from the National Pain Strategy.