Career Enhancement Program

职业发展研究中心 CEP主任：Simon Powell，MD PhD CEP联合主任：Jorge Reis-Filho，MD PhD 摘要： SPORE职业提升计划（CEP）旨在为独立的医生和科学家做好准备。 乳腺癌的转化研究。我们的目标是，调查人员通过这一进程的支持， 将在职业生涯中从事乳腺癌的转化研究， 领导者在外地。纪念斯隆凯特琳癌症中心（MSKCC）非常适合这项任务，因为 我们曼哈顿校区和附属机构的科学和临床环境，以及我们悠久的传统 培养最高质量的医生和科学家。我们的机构环境包括许多NIH 培训赠款，包括用于翻译科学培训的K12补助金，用于培养翻译科学博士的T32补助金 肿瘤学研究，临床研究与临床和转化相结合的证书课程 威尔康奈尔大学的科学课程，以及一个完善的初级教师指导计划。我们计划利用 未来5年，SPORE职业发展基金将用于加强现有的正式辅导计划。 我们将鼓励更多的实习医生专注于乳腺癌的转化研究，特别是 利用DNA修复缺陷和乳腺癌遗传不稳定性的特定模式的新知识， 为乳腺癌患者提供有针对性的治疗。我们将努力吸引基本的， 翻译和人口科学家谁有兴趣把自己的职业生涯，使发现， 具有临床应用的现实潜力。MSKCC Breast SPORE职业的具体目标 增强计划是为了支持初级教师的指导和研究， 乳腺癌研究，采用临床和实验室/人口科学双导师模式， 招募和指导新的初级教员从事乳腺癌转化研究。

CAREER ENHANCEMENT PROGRAM RESEARCH PLAN CEP Director: Simon Powell, MD PhD CEP Co-Director: Jorge Reis-Filho, MD PhD Abstract: The SPORE Career Enhancement Program (CEP) aims to prepare physicians and scientists for independent careers in translational research in breast cancer. Our goal is that investigators supported through this process will spend their professional lifetimes conducting translational research in breast cancer and become academic leaders in the field. Memorial Sloan Kettering Cancer Center (MSKCC) is ideally suited for this task, because of the scientific and clinical environment at our Manhattan campus and affiliated institutions, and our long tradition of training physicians and scientists of the highest quality. Our institutional environment includes numerous NIH training grants, including a K12 grant for translational science training, a T32 grant to train PhDs in translational research in Oncology, a Certificate Program in Clinical Investigation integrated with the Clinical and Translational Science Program at Weill Cornell, and a well-established junior faculty mentoring program. We plan to use the SPORE Career Enhancement funds over the next 5 years to enhance the existing formal mentoring programs. We will encourage more physician trainees to focus on translational research in breast cancer, in particular to leverage the emerging knowledge of DNA repair defects and specific patterns of genetic instability in breast cancers to deliver targeted treatments to individual breast cancer patients. We will strive to attract basic, translational and population scientists who are interested in devoting their careers to making discoveries that have a realistic potential to clinical applications. The specific aims of the MSKCC Breast SPORE Career Enhancement Program are to support the mentoring and research of junior faculty for careers in translational research in breast cancer, using a dual clinical and laboratory/population science mentorship model, and to recruit and mentor new junior faculty members to work in breast cancer translational research.