Career Enhancement Program

职业提升计划研究计划 CEP主任：西蒙·鲍威尔，医学博士 CEP联席主任：豪尔赫·里斯-菲略，医学博士 摘要： 孢子职业提升计划(CEP)旨在为独立医生和科学家做好准备 从事乳腺癌的转译研究。我们的目标是在整个过程中为调查人员提供支持 将在他们的职业生涯中从事乳腺癌的翻译研究，并成为学者 该领域的领先者。纪念斯隆·凯特琳癌症中心(MSKCC)非常适合这项任务，因为 曼哈顿校区及其附属机构的科学和临床环境，以及我们的悠久传统 培养最高素质的医生和科学家。我们的制度环境包括许多美国国立卫生研究院 培训赠款，包括用于翻译科学培训的K12赠款，用于培训翻译博士的T32赠款 肿瘤学研究--临床研究与翻译相结合的临床研究证书项目 威尔康奈尔大学的科学计划，以及一个久负盛名的初级教师指导计划。我们计划使用 未来5年的孢子职业提升基金，用于加强现有的正式指导计划。 我们将鼓励更多的见习医生专注于乳腺癌的翻译研究，特别是 利用关于DNA修复缺陷和乳房遗传不稳定的特定模式的新兴知识 为个别乳腺癌患者提供有针对性的治疗。我们将努力吸引基本的， 翻译和人口科学家，他们有兴趣将他们的职业生涯致力于发现 具有临床应用的现实潜力。MSKCC乳腺孢子职业生涯的具体目标 加强计划是为了支持初级教师在翻译职业方面的指导和研究 乳腺癌研究，使用临床和实验室/人口科学双重指导模式，并 招募和指导新的初级教员从事乳腺癌转化研究。

CAREER ENHANCEMENT PROGRAM RESEARCH PLAN CEP Director: Simon Powell, MD PhD CEP Co-Director: Jorge Reis-Filho, MD PhD Abstract: The SPORE Career Enhancement Program (CEP) aims to prepare physicians and scientists for independent careers in translational research in breast cancer. Our goal is that investigators supported through this process will spend their professional lifetimes conducting translational research in breast cancer and become academic leaders in the field. Memorial Sloan Kettering Cancer Center (MSKCC) is ideally suited for this task, because of the scientific and clinical environment at our Manhattan campus and affiliated institutions, and our long tradition of training physicians and scientists of the highest quality. Our institutional environment includes numerous NIH training grants, including a K12 grant for translational science training, a T32 grant to train PhDs in translational research in Oncology, a Certificate Program in Clinical Investigation integrated with the Clinical and Translational Science Program at Weill Cornell, and a well-established junior faculty mentoring program. We plan to use the SPORE Career Enhancement funds over the next 5 years to enhance the existing formal mentoring programs. We will encourage more physician trainees to focus on translational research in breast cancer, in particular to leverage the emerging knowledge of DNA repair defects and specific patterns of genetic instability in breast cancers to deliver targeted treatments to individual breast cancer patients. We will strive to attract basic, translational and population scientists who are interested in devoting their careers to making discoveries that have a realistic potential to clinical applications. The specific aims of the MSKCC Breast SPORE Career Enhancement Program are to support the mentoring and research of junior faculty for careers in translational research in breast cancer, using a dual clinical and laboratory/population science mentorship model, and to recruit and mentor new junior faculty members to work in breast cancer translational research.