Pilot/Feasibility

摘要 海王星促进肾病综合征(NS)翻译科学的目标的核心是维护 基础设施和资金机会，鼓励具有不同兴趣和专业知识的调查人员 利用海王星的智力资源、观察临床数据、生物显微镜、数字病理档案、 和派生的数据集。在更新建议中，海王星计划继续并扩大非凡的 其试点和辅助研究方案(PAS)的成功。海王星加速肾小球疾病的目标 在过去的九年里，通过包容不同的科学兴趣进行的研究得到了PA的很好的服务。 几年来，该网络的数据和生物库资源已经成熟。这些产品的使用呈稳步增长趋势 从一大批调查人员的演讲、论文和资助提案的数量来看，资源是显而易见的。 网络内部和外部。通过与NephCure肾脏国际基金会(NKI)的密切合作， 作为领先的肾小球疾病倡导基金会，海王星已经资助了10个试点项目，并处理了112个项目 过去九年的附属研究建议。值得注意的是，这112项辅助研究中有32项(30%) 委员会批准的项目得到了海王星外部的支持。

ABSTRACT Central to NEPTUNE's goals for facilitating translational science in Nephrotic Syndrome (NS) is the maintenance of an infrastructure and funding opportunities that encourages investigators with diverse interests and expertise to use NEPTUNE's intellectual resources, observational clinical data, biospecimens, digital pathology archive, and derived data sets. In the renewal proposal, NEPTUNE plans to continue and expand on the remarkable success of its Pilot and Ancillary Studies Program (PAS). NEPTUNE's goal of accelerating glomerular disease research by being inclusive of diverse scientific interests has been well served by the PAS during the past nine years as the network's data and biobank resources have matured. A steadily increasing trend of use of these resources are evident by the volume of talks, papers, and funded proposals from a large pool of investigators inside and outside the network. By its close association with NephCure Kidney International Foundation (NKI), a leading glomerular disease advocacy foundation, NEPTUNE has funded 10 pilot projects and processed 112 ancillary study proposals during the past nine years. Remarkably, 32 (30%) of these 112 ancillary study committee-approved projects received support external to NEPTUNE.