Pilot/Feasibility

摘要 NEPTUNE促进肾病综合征（NS）转化科学的核心目标是维护 鼓励具有不同兴趣和专业知识的调查人员的基础设施和资金机会 利用NEPTUNE的智力资源，观察性临床数据，生物标本，数字病理学档案， 和衍生数据集。在更新提案中，NEPTUNE计划继续并扩大卓越的 其试点和辅助研究计划（PAS）的成功。NEPTUNE加速肾小球疾病的目标 在过去的九年里，PAS通过包容各种科学兴趣，很好地服务了研究 多年来，网络的数据和生物库资源已经成熟。使用这些工具的趋势稳步增加， 大量的研究人员进行了大量的会谈、撰写了大量的论文，并提出了大量的资助建议，这些都证明了我们拥有足够的资源 在网络内外。通过与肾病治疗国际基金会（NKI）的密切联系， 作为一个领先的肾小球疾病倡导基金会，NEPTUNE资助了10个试点项目，并处理了112个项目。 在过去九年中，值得注意的是，这112项辅助研究中有32项（30%） 委员会批准的项目得到了NEPTUNE外部的支持。

ABSTRACT Central to NEPTUNE's goals for facilitating translational science in Nephrotic Syndrome (NS) is the maintenance of an infrastructure and funding opportunities that encourages investigators with diverse interests and expertise to use NEPTUNE's intellectual resources, observational clinical data, biospecimens, digital pathology archive, and derived data sets. In the renewal proposal, NEPTUNE plans to continue and expand on the remarkable success of its Pilot and Ancillary Studies Program (PAS). NEPTUNE's goal of accelerating glomerular disease research by being inclusive of diverse scientific interests has been well served by the PAS during the past nine years as the network's data and biobank resources have matured. A steadily increasing trend of use of these resources are evident by the volume of talks, papers, and funded proposals from a large pool of investigators inside and outside the network. By its close association with NephCure Kidney International Foundation (NKI), a leading glomerular disease advocacy foundation, NEPTUNE has funded 10 pilot projects and processed 112 ancillary study proposals during the past nine years. Remarkably, 32 (30%) of these 112 ancillary study committee-approved projects received support external to NEPTUNE.