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Training Program in Clinical & Translationa Research in Human Glomerular Disease

临床培训计划

基本信息

批准号：
7937389
负责人：
LAWRENCE B. HOLZMAN
金额：
$ 54.48万
依托单位：
UNIVERSITY OF MICHIGAN AT ANN ARBOR
依托单位国家：
美国
项目类别：
财政年份：
2009
资助国家：
美国
起止时间：
2009-09-08 至 2014-06-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/7937389
关键词：
Address Adherence American Area Award Bioinformatics Biological Markers Clinical Clinical Data Clinical Research Clinical Trials Commit Doctor of Philosophy Education Environment Epidemiology Faculty Fellowship Fellowship Program Financial Support Foundations Funding Generations Genetic Grant Home environment Human Human Genetics Individual Institution Investigation Kidney Laboratories Learning Left Mentors Michigan Modeling Molecular Molecular Biology Nephrology Nephrotic Syndrome Participant Pathology Patient Care Pilot Projects Postdoctoral Fellow Process Publishing Rare Diseases Renal glomerular disease Research Research Design Research Infrastructure Research Personnel Research Project Grants Research Training Resources Science Scientist Silicon Dioxide Source Specimen Systems Biology Time Training Training Programs Translational Research United States National Institutes of Health Universities Vocational Guidance Work Writing career career development design early experience experience interest meetings oncology programs responsible research conduct statistics tool

项目摘要

Training Program: The NSRDCRN Training Program in Clinical and Translational Research in Human Glomerular Disease 1. Introduction 1.1. Objectives: The NSRDCRN training program is designed for advanced post-doctoral and junior faculty trainees, or established investigators interested in redirecting their investigative focus, who are preparing to become independent investigators in clinical and translational research in human glomerular disease. Training will be individually tailored for each trainee, combining a didactic program with a mentored research experience that employs the resources of the Nephrotic Syndrome Rare Disease Consortium. 1.2. Rationale: As detailed elsewhere in this NSRDCRN application, clinical investigation of human glomerular disease has progressed slowly over the past several decades leaving renal practitioners with inadequate information to properly direct their patient's care. The absence of an investigative infrastructure and insufficient funding have impeded the advances that are now possible using modern genetics, molecular biology, and systems biology tools. These same tools have propelled advances in fields such as oncology where multiple rare diseases predominate. Without a collaborative infrastructure, relatively few established investigators have emerged to conduct glomerular disease investigations. Moreover, given poor opportunity, few potential investigators have been drawn to this area of study and few are presently training to carry this field forward. The creation of the first North American collaborative network to study rare glomerular diseases provides opportunity and a valuable resource that will be exploited to expand the pool of scientists who employ modern experimental approaches for work in this field. To address this need, the NSRDCRN will create a program that provides talented trainees interested in studying glomerular disease with financial support, a strong mentoring research environment, and access to the unique resources, clinical data, or specimens assembled by the NS Rare Disease Consortium.

培训计划：NSRDCRN临床和翻译研究培训计划人类肾小球疾病 1.引言 1.1.目标：NSRDCRN培训计划是为高级博士后和初级教师设计的受训人员或有兴趣改变其调查重点的资深调查人员，他们正准备成为人类肾小球疾病临床和翻译研究的独立研究人员。培训将为每个学员量身定做，结合授课计划和指导计划利用肾病综合征罕见病联盟资源的研究经验。 1.2.基本原理：正如在NSRDCRN申请的其他地方详细描述的那样，对人类的临床研究在过去的几十年里，肾小球疾病进展缓慢，给肾脏医生留下了信息不足，无法正确指导患者的护理。缺乏调查基础设施而资金不足阻碍了现在利用现代遗传学取得的进展，分子生物学和系统生物学工具。这些工具推动了以下领域的进步多种罕见疾病占主导地位的肿瘤学。如果没有协作基础设施，相对较少已经出现了进行肾小球疾病调查的老牌调查人员。此外，由于机会很少，这一研究领域吸引的潜在研究人员很少，目前也没有多少人接受培训以推动这一领域的发展。北美第一个研究罕见肾小球疾病的合作网络的建立提供了机会和宝贵的资源，将被利用来扩大使用现代实验方法在这一领域工作的科学家队伍。为了满足这一需求，NSRDCRN将创建一个项目，为对研究肾小球疾病感兴趣的有才华的受训者提供资金支持、强大的指导性研究环境，以及访问由NS罕见疾病联盟收集的独特资源、临床数据或标本。