Development of a Standardized, Reliable and Easy-to-Use Clinical Instrument to Measure First Ray Mobility and Position of the Medial Forefoot to Assist with Clinical Decisions and Treatments
开发标准化、可靠且易于使用的临床仪器来测量前足内侧的第一射线活动度和位置,以协助临床决策和治疗
基本信息
- 批准号:10483379
- 负责人:
- 金额:$ 25.96万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2022
- 资助国家:美国
- 起止时间:2022-09-16 至 2024-08-31
- 项目状态:已结题
- 来源:
- 关键词:AddressAlgorithmsAnkleAttentionBiomechanicsCapitalCellular PhoneClinicClinicalClinical assessmentsComputerized Medical RecordConsultDataData SetDeformityDegenerative DisorderDegenerative polyarthritisDevelopmentDevicesDiabetic FootDiabetic Foot UlcerDoctor of PhilosophyEngineeringEquationExhibitsFlatfootFocus GroupsFundingGaitGoalsHallux LimitusHallux RigidusHallux ValgusHallux structureHandHealthHeightHip region structureHollyIncidenceIndividualInferiorInvestigationJointsKneeLaboratoriesLengthLimb structureManualsManufacturer NameMarketingMeasurementMeasuresMechanicsMedialMetatarsal bone structureMetatarsalgiaMetatarsophalangeal joint structureMissionMotionNational Institute of Arthritis and Musculoskeletal and Skin DiseasesOperative Surgical ProceduresOrthopedicsOsteotomyOutcomePainPaperPathologicPathologyPatientsPeer ReviewPhalanxPhasePhysiciansPlant RootsPodiatryPositioning AttributeProceduresProxyPublicationsPublishingQuestionnairesResearchRotationSelf AssessmentSmall Business Innovation Research GrantSourceStandardizationStructureSubgroupSurgeonTalipes cavusTechnologyTestingTimeTransducersVisualWeightbasecohortcostdesigndisabilityencryptionfallsflexibilityfootimprovedindexinginnovationinstrumentinstrumentationlaptopphysical therapistportabilitypower analysisprototyperesponsesmartphone Applicationtoolusabilityuser-friendlywalking speedwireless
项目摘要
Osteoarthritis (OA) research, a primary component of the NIAMS mission, has focused on the hip, knee, and
hand, with sparse attention to the foot. First metatarsophalangeal (MTP) joint OA (Hallux Rigidus), a source of
substantial pain and limited mobility, is the most common degenerative disease in the foot. Excessive or
insufficient 1st ray mobility (FRM) has been associated with numerous painful, disabling, and limb threatening
pathologies including: tarsometatarsal OA, Hallux Valgus (HV), Hallux Rigidus (HR), metatarsalgia, diabetic
foot ulceration, pes cavus, and pes planus. First ray (medial cuneiform, 1st metatarsal, proximal phalanx, and
hallux) mobility is the superior or inferior displacement of these bony structures in response to a vertically
applied load. While a couple of laboratory devices exist to test 1st ray hypermobility (FRM ≥8mm), there are no
commercially available, reliable, user friendly, FRM devices for the clinic. The study goal is to redesign and
improve the 1st Ray Mobility and Position (MAP1st) version 1 (V1) prototype (PCT/US21/22791) to provide a
clinically viable instrument to measure 1st ray mobility and position. MAP1st V1 has several limitations, including
i) weight, ii) ungrounded hindfoot, iii) visual measurement, iv) tethered laptop, and v) manual data entry. The
Specific Aim is to develop MAP1st version 2 (V2) to increase the reliability, utility, efficiency, and ease
of use for measuring FRM, position, and stiffness. In MAP1st V2, a transducer will measure mobility and
position while a smartphone-based App will replace the laptop and compute stiffness. Outcomes will be stored
in an encrypted file and transferred to electronic medical records. Using this device, and guided by power
analysis, a data set (n=80 feet) will be acquired from 20 healthy individuals with asymptomatic rectus (nrf = 20)
and planus (npf = 20) feet, 10 patients with hallux valgus feet (nhvf = 20) and 10 patients with hallux rigidus feet
(nhrf = 20). Intra-rater and inter-rater reliability will be assessed from replicated measures, while subgroup
differences will also be examined. Device utility will be assessed by distinguishing FRM between the healthy
and pathologic groups using Generalized Estimation Equations (GEE). A usability questionnaire will assess
clinician (MD, DPM, DPT, technician) ease of use for V1 versus V2. Three hypotheses will be tested: (1) Intra-
rater and inter-rater reliability will exhibit an ICC (2,1)>0.75 for use of MAP1st V2; (2) First ray mobility, position,
and stiffness will be different across individuals with asymptomatic rectus, asymptomatic planus, hallux valgus,
and hallux rigidus feet demonstrating device utility; (3) Usability and efficiency will be improved between
MAP1st V1 and V2. This investigational team has collaborated on 10+ projects and co-published 50+
publications on foot biomechanics. Further, pilot data supports MAP1st ability to detect hypermobility in planus
vs. rectus feet. Hence, a smooth, successful completion of this project is anticipated. MAP1st V2 will address
an unmet clinical need by providing reliable first ray mobility and position measurements for clinical
assessment which could be used to formulate treatment algorithms that will ultimately benefit the patient.
骨关节炎(OA)研究是NIAMS任务的主要组成部分,主要集中在髋关节、膝关节和下肢
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Howard J. Hillstrom其他文献
Retrospective analysis of neurapraxia and axonotmesis injuries of select peripheral nerves of the foot and ankle and their conservative and surgical treatment (external neurolysis and neurectomy)
- DOI:
10.1016/s1067-2516(99)80051-9 - 发表时间:
1999-05-01 - 期刊:
- 影响因子:
- 作者:
J. Peter Barrett;Michael S. Downey;Howard J. Hillstrom - 通讯作者:
Howard J. Hillstrom
Comparing surface topographic range of motion in pediatric patients with Scheuermann kyphosis to healthy controls
- DOI:
10.1007/s43390-025-01126-8 - 发表时间:
2025-06-11 - 期刊:
- 影响因子:1.800
- 作者:
Jenna L. Wisch;Akshitha Adhiyaman;Ankush Thakur;Colson P. Zucker;Benjamin N. Groisser;Patrick Nian;Amith Umesh;Ram Haddas;M. Timothy Hresko;Matthew E. Cunningham;John S. Blanco;Howard J. Hillstrom;Roger F. Widmann;Jessica H. Heyer - 通讯作者:
Jessica H. Heyer
The Effect of Pitch Count on Shoulder Kinematics and Strength in Adolescent Baseball Pitchers
- DOI:
10.1016/j.jse.2014.06.010 - 发表时间:
2014-09-01 - 期刊:
- 影响因子:
- 作者:
Jennifer Bido;Mandi W. Gibbons;Andrew Kraszewski;Jocelyn F. Hafer;Jessica Graziano;Michael Levinson;Sherry I. Backus;Howard J. Hillstrom;Andreas Kontaxis;Stephen Fealy - 通讯作者:
Stephen Fealy
Mapping glenohumeral laxity: effect of capsule tension and abduction in cadaveric shoulders
- DOI:
10.1016/j.jse.2017.10.019 - 发表时间:
2018-04-01 - 期刊:
- 影响因子:
- 作者:
Andrew P. Kraszewski;Stephanie W. Mayer;Andreas Kontaxis;Howard J. Hillstrom;Ali Sheikhzadeh;Russell P. Warren - 通讯作者:
Russell P. Warren
Robotic-assisted pedicle screw placement improves accuracy, precision, and breach rates compared with freehand and image-guided navigation techniques: a cadaveric study
- DOI:
10.1007/s43390-025-01150-8 - 发表时间:
2025-07-21 - 期刊:
- 影响因子:1.800
- 作者:
Gregory S. Kazarian;Benjamin N. Groisser;Ankush Thakur;Mihir S. Dekhne;Howard J. Hillstrom;Austin C. Kaidi;Jung Kee Mok;Akshitha Adhiyaman;Olivia C. Tracey;Colson Zucker;Jenna L. Wisch;Matthew Cunningham;M. Timothy Hresko;Ram Haddas;John Blanco;Douglas N. Mintz;Ryan E. Breighner;Roger F. Widmann;Jessica H. Heyer - 通讯作者:
Jessica H. Heyer
Howard J. Hillstrom的其他文献
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{{ truncateString('Howard J. Hillstrom', 18)}}的其他基金
Development of a Standardized, Reliable and Easy-to-Use Clinical Instrument to Measure First Ray Mobility and Position of the Medial Forefoot to Assist with Clinical Decisions and Treatments
开发标准化、可靠且易于使用的临床仪器来测量前足内侧的第一射线活动度和位置,以协助临床决策和治疗
- 批准号:
10772958 - 财政年份:2022
- 资助金额:
$ 25.96万 - 项目类别:
Development of a Geometric Forefoot Model: A tool for Clinical Decision Making
几何前足模型的开发:临床决策的工具
- 批准号:
7284896 - 财政年份:2006
- 资助金额:
$ 25.96万 - 项目类别:
Development of a Geometric Forefoot Model: A tool for Clinical Decision Making
几何前足模型的开发:临床决策的工具
- 批准号:
7018592 - 财政年份:2006
- 资助金额:
$ 25.96万 - 项目类别:
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