Momitor: Wearable Technology for Early Detection of Postpartum Hemorrhage
Momitor:用于早期发现产后出血的可穿戴技术
基本信息
- 批准号:10483278
- 负责人:
- 金额:$ 24.47万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2022
- 资助国家:美国
- 起止时间:2022-05-01 至 2024-04-30
- 项目状态:已结题
- 来源:
- 关键词:AddressAdmission activityAdoptionAffectAlgorithmsAtopobium vaginaeBirthBirthing CentersBloodBlood CirculationBlood TransfusionBlood VolumeCesarean sectionChargeChildbirthClinicalClinical ManagementDataData CollectionDetectionDeteriorationDevicesEarly DiagnosisEnsureFeesFundingFutureHemorrhageHemorrhagic ShockHospitalsHourHypovolemiaIncomeInsurance CarriersIntensive CareInterventionLegLength of StayLifeLimb structureLinkLiteratureMaternal MortalityMeasuresMinority GroupsMonitorMorbidity - disease rateMothersObservational StudyOperating RoomsOrganPatient CarePatient-Focused OutcomesPatientsPennsylvaniaPharmaceutical PreparationsPhasePhotoplethysmographyPostpartum HemorrhagePostpartum PeriodPostpartum WomenRaceRadioRiskRunningSmall Business Technology Transfer ResearchSuggestionSymptomsSystemTechniquesTimeUnited States National Institutes of HealthVaginal delivery procedureVisualWomanWorkloadalgorithm developmentarmbaseclinical decision supportclinical riskclinically actionablecloud basedcostdashboarddirect applicationearly screeningimproved outcomemortalitypatient tolerabilityperipheral bloodprototyperesponsesmart watchstandard of caretransmission processtrauma carewearable devicewireless fidelity
项目摘要
Abstract:
Postpartum hemorrhage (PPH) is the leading cause of maternal death worldwide and
disproportionately affects minority populations. PPH is defined as a large loss of blood within 24 hours
of birth. If detected early enough, effective clinical management solutions exist that significantly reduce
mortality. Current standard of care for detecting PPH rely on vital sign monitoring and visually
inspecting the mother’s pad to estimate blood loss. However, visual inspection of pads is subjective
and error prone while deterioration in vital signs are delayed indicators of maternal blood volume
changes. Consequently, early and accurate detection of PPH remains a significant clinical challenge.
Vasowatch LLC is developing an automated, continuous, and minimally burdensome monitoring
system, called the Momitor, that can (1) accurately and rapidly identify symptoms of PPH and (2)
deliver real-time and actionable clinical decision support linked to the identified PPH symptoms. The
Momitor system will consist of a wearable device worn on an extremity consisting of LEDs,
phototransistors, Wi-Fi radio, and battery. The non-invasive wearable will collect
photoplethysmography (PPG) waveform data, run an algorithm that identifies the onset of waveform
changes suggestive of PPH, and alert clinical staff to assess the mother through a cloud-based system
with SMS and dashboard alerting capabilities. During PPH the body automatically diverts blood from
non-vital extremities to vital organs as a lifesaving measure – which delays deterioration in vital signs.
Consequently, rather than relying on error-prone visual inspection of sanitary pads and monitoring for
delayed vital sign changes, the Momitor aims to screen for the mother’s automatic compensatory
response consistent with PPH and hypovolemia. In this Phase I STTR, we will demonstrate proof-of-
concept for detecting PPH before vital sign deterioration based on a modified compensatory reserve
estimation by demonstrating an algorithm that can accurately detect PPH before existing standard of
care, prototyping a wearable device that can collect and analyze PPG data for PPH from admission
to 24-hours postpartum. Receipt of NIH funds will allow us to demonstrate proof-of-concept of the
Momitor and provide sufficient evidence to pursue FDA Breakthrough Device designation. We believe
this solution will address an urgent need and will broadly be appealing to hospitals, resulting in lower
costs and greatly improved outcomes for patients – regardless of race. Expansion into non-hospital-
based birth centers will follow.
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项目成果
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