3D Image Analysis Software for Breast Reconstruction Surgical Planning, Outcome Assessment & Clinical Consultation
用于乳房重建手术规划、结果评估的 3D 图像分析软件
基本信息
- 批准号:10484568
- 负责人:
- 金额:$ 20.38万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2022
- 资助国家:美国
- 起止时间:2022-04-01 至 2024-03-31
- 项目状态:已结题
- 来源:
- 关键词:3-DimensionalAddressAlgorithmic AnalysisAmericanAppearanceAutologousBilateralBlindedBody ImageBreastBreast Cancer PatientBreast Cancer TreatmentBreast Cancer survivorCancer CenterCancer EtiologyCancer PatientCancer SurvivorCaringCessation of lifeClinicalClinical assessmentsCommunicationComputer SimulationComputer softwareConsultationsDataDescriptorDetectionDevelopmentEquipmentEstheticsEvaluationFeasibility StudiesFutureHandHeightImageImage AnalysisImaging DeviceImplantLegal patentMammaplastyMastectomyMeasurementMeasuresMedicalMethodsModelingMorphologyOperative Surgical ProceduresOutcomeOutcome AssessmentPatient PreferencesPatient imagingPatientsPerformancePersonal SatisfactionPhasePostoperative PeriodProceduresProcessPtosisQuality of lifeReconstructive Surgical ProceduresRecoveryResearchScheduleShapesSiteSmall Business Technology Transfer ResearchSomatotypeSurfaceSurgeonSurgical OncologySurvivorsSystemThree-Dimensional ImageThree-Dimensional ImagingTimeTissuesUniversitiesUniversity of Texas M D Anderson Cancer CenterVisualVisualizationVisualization softwareWidthWomanautomated algorithmautomated analysisbasecancer carecancer surgeryclinical outcome assessmentclinically relevantcohortcommercializationcosteducation planningexpectationexperiencehealth related quality of lifeimprovedinnovationmalignant breast neoplasmmorphometrymultidisciplinarynoveloutcome predictionpatient expectationphase 1 studyportabilitypreclinical evaluationpreferenceprototypequantitative imagingreconstructionresearch clinical testingsatisfactionself esteemside effectsimulationskillssoftware developmentsuccesssurgery outcomethree-dimensional modelingthree-dimensional visualizationtooltreatment choicetreatment planningusabilityvirtual surgery
项目摘要
Abstract
Breast cancer is the second leading cause of cancer death in American women. Breast reconstruction
surgery is an important component of the breast cancer treatment process, that is used to rebuild a breast form
that has been removed due to cancer surgery. It is integral to improving the cancer patient's health-related quality
of life. However, planning and evaluation of the surgery are done subjectively, and the result is not always
aesthetically satisfactory.
Standards for breast reconstruction have evolved over the past two decades, and patients and surgeons
alike expect natural, symmetrical -looking surgical outcomes. Surgeons rely on their personal experience and
on subjective visual assessment skills to achieve these results. Similarly, aesthetic outcome assessment
methods, following surgery, are rather subjective, and are based on observer evaluation of physical changes in
breast morphology and symmetry. With recent developments in three-dimensional (3D) imaging, there is now
an opportunity to develop software that permit use of breast morphometry and computerized simulations for
treatment planning, clinical consultation, and objective assessment of postoperative results. Currently, there is
no stand-alone, imaging-device independent software for a surgeon to automate measurements for objectively
formulating a surgical plan or generate realistic simulations of breast shape.
To address this challenge, we propose the development of software for quantitative assessment of breast
shape. 3D imaging has been validated for the clinical assessment of breast aesthetics but has seen limited use
for simulation and surgical planning due to the exorbitant costs (~$100-300K) of imaging equipment and lack of
appropriate image analysis tools. Low-cost (~8K), portable hand-held 3D scanners are now available, but
software for enabling breast morphometric analysis for surgical planning is lacking. In this Phase I STTR study,
Soft Imaging, LLC is collaborating with the University of Houston (UH) and The University of Texas MD Anderson
Cancer Center to develop 3D image analysis software that will utilize innovative and novel 3D image analysis
algorithms for enabling (1) automated approaches for breast morphometry and surgical planning and (2) employ
a parametric modeling approach based on 3D spherical harmonics (SPHARM) to model breast shape, to provide
realistic simulations for visualization during clinical consultations. This will help breast cancer patients make
informed decisions about their breast reconstruction treatment choices, calibrate her expectations, and be more
comfortable with her treatment choices.
At the completion of this Phase I feasibility study, a future Phase II project, will develop a prototype for
clinical testing at multiple sites, followed by Phase III commercialization. Applications would improve breast
cancer care in several ways, such as; surgical planning, enabling personalized simulations of surgical outcomes,
surgical education, and planning of comfortable postoperative garments (bras) for use during surgical recovery.
摘要
项目成果
期刊论文数量(0)
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科研奖励数量(0)
会议论文数量(0)
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Fatima Aziz Merchant其他文献
Fatima Aziz Merchant的其他文献
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{{ truncateString('Fatima Aziz Merchant', 18)}}的其他基金
3D Image Analysis Software for Breast Reconstruction Surgical Planning, Outcome Assessment & Clinical Consultation
用于乳房重建手术规划、结果评估的 3D 图像分析软件
- 批准号:
10589908 - 财政年份:2022
- 资助金额:
$ 20.38万 - 项目类别:
3D Breast Anatomy Analysis in Cancer Treatment Planning and Outcome Assessment
癌症治疗计划和结果评估中的 3D 乳房解剖分析
- 批准号:
7219169 - 财政年份:2007
- 资助金额:
$ 20.38万 - 项目类别:
A Virtual Reality Environment for Genomic Data Visualization
基因组数据可视化的虚拟现实环境
- 批准号:
7218900 - 财政年份:2007
- 资助金额:
$ 20.38万 - 项目类别:
Low Cost Automated Urinalysis using Spectral Data
使用光谱数据进行低成本自动化尿液分析
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6883492 - 财政年份:2005
- 资助金额:
$ 20.38万 - 项目类别:
Automated Detection of Gene Duplications or Deletions
自动检测基因重复或缺失
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6874478 - 财政年份:2000
- 资助金额:
$ 20.38万 - 项目类别:
Automated Detection of Gene Duplications or Deletions
自动检测基因重复或缺失
- 批准号:
6742066 - 财政年份:2000
- 资助金额:
$ 20.38万 - 项目类别:
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