International Epidemiology Databases to EvaluateAIDS (IeDEA) Renewal 4
用于评估艾滋病的国际流行病学数据库 (IeDEA) 更新 4
基本信息
- 批准号:10488077
- 负责人:
- 金额:$ 168.78万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2006
- 资助国家:美国
- 起止时间:2006-07-01 至 2026-04-30
- 项目状态:未结题
- 来源:
- 关键词:AIDS populationAIDS/HIV problemAchievementAcquired Immunodeficiency SyndromeAddressAdolescentAdultAffectAfricaAfricanAgeAgingAlgorithmsAnxietyBurkina FasoCaringCervical Cancer ScreeningCharacteristicsChildChronicClientClinicClinicalClinical ResearchCollaborationsContinuity of Patient CareCountryDataData SourcesDatabasesDecentralizationDepressed moodDevelopmentDiabetes MellitusDiagnosisEnsureEpidemicEpidemiologyEventExposure toFosteringFranceFundingGhanaGoalsGuidelinesHIVHIV InfectionsHIV SeropositivityHIV-1HIV-2HealthHealth Services AccessibilityHousingHuman PapillomavirusHuman ResourcesHuman immunodeficiency virus testHyperlipidemiaHypertensionImmuneIndividualInfantInformation SystemsInternationalInterventionIvory CoastKnowledgeLife ExpectancyMaliMalignant NeoplasmsMeasuresMental DepressionMental HealthMissionMorbidity - disease rateNational Institute of Allergy and Infectious DiseaseNigeriaNigerianNongovernmental OrganizationsNutrition DisordersOutcomePersonsPopulationPositioning AttributePrevalencePreventive therapyProceduresPrognosisProspective cohortQuality of lifeRecommendationRecoveryResearchResearch InfrastructureResourcesSenegalSentinelSiteStandardizationSubstance Use DisorderTestingThermal Ablation TherapyTogoTrainingTreatment outcomeTuberculosisTuberculosis diagnosisUniversitiesUpdateViralViral Load resultVulnerable PopulationsWomanantiretroviral therapybaseclinical centercohortcomorbiditydata qualitydesignepidemiology studyexperiencefemale sex workerfollow-upfood insecurityimprovedinterpersonal therapymeetingsmen who have sex with mennon-alcoholic fatty liver diseasepopulation basedpre-exposure prophylaxisprogramsprospectivereproductivescale upscreeningservice programstrenduptakeyoung woman
项目摘要
PROJECT SUMMARY/ABSTRACT
West Africa holds a significant burden of the HIV epidemic with approximately 3.5 million people living with HIV
(PLHIV). Despite calls for action to support access to universal test and treat in the region, West Africa
experience major challenges ensuring a continuum of HIV care in adequacy with the latest UNAIDS
recommendations. To address these core challenges, the IeDEA West Africa Collaboration relies on a unique
network of cohorts in West Africa with a mission to conduct hypothesis-driven epidemiological research on
barriers in access to care as well as on the prognosis and outcomes of PLHIV, including adults, adolescents and
children in care, as well as HIV-exposed children. Our five-year research plan will focus on scientific questions
that contributing cohorts can hardly answer separately with a unique partnership between English-speaking and
French-speaking countries in the region. The overarching specific aims of our program will be: 1) To identify an
describe individual and structural barriers associated with the continuum of HIV care, from HIV testing to retention
in care and viral suppression throughout West Africa, 2) To leverage our existing network to establish a cohort
of HIV Key Populations including female sex workers and men who have sex with men in IeDEA West Africa, 3)
To determine the burden of non-communicable diseases and evaluate their interplay with HIV infection. Our
collaboration has supported one of the most robust epidemiological and clinical research infrastructure in the
region, housing data on close to 40,000 adults (including 883 HIV-2 et 843 HIV-1/2) and 15,814 children (6,515
children exposed to HIV, 7,041 on ART and 2,258 children living with HIV not already on ART) in seven countries
in the region (Benin, Burkina Faso, Côte d’Ivoire, Ghana, Mali, Togo and Senegal). The next round will involve
21 HIV clinical centers in eight countries (Benin, Burkina Faso, Cote d’Ivoire, Ghana, Mali, Nigeria, Senegal and
Togo). Among them, eight clinics are new collaborating centers. The IeDEA West Africa collaboration is
coordinated at the University of Bordeaux, France with a regional Office hosted by the PACCI program, a
research-oriented non-governmental organization situated in Abidjan, Côte d’Ivoire. This research team has a
long-lasting experience in observational HIV research including large-scale prospective cohorts in West Africa.
Data will be collected from affiliated cohorts every year according to standardized procedures and will be merged
at the coordinating center in Bordeaux. Capacity building in participating centers will include funding for local
human resources, training on data quality, on-site technical support and annual meetings to reinforce the
technical and scientific network. At the completion of this funding cycle, we intend to address major research
gaps including a better knowledge the various comorbidities affecting PLHIV in West Africa. Our cohorts will be
more representative of the regional HIV epidemic and will capture important data on Key Populations to inform
target interventions for these vulnerable groups.
项目摘要/摘要
西非的艾滋病毒疫情负担沉重,约有350万艾滋病毒携带者
(PLHIV)。尽管呼吁采取行动支持该区域的普遍检测和治疗,但西非
经历重大挑战,确保利用最新的联合国艾滋病规划署充分提供持续的艾滋病毒护理
建议。为了应对这些核心挑战,IeDEA西非合作依靠一种独特的
西非队列网络,任务是进行假说驱动的流行病学研究
获得护理方面的障碍以及对艾滋病毒的预后和结果的障碍,包括成人、青少年和
在看护中的儿童,以及感染艾滋病毒的儿童。我们的五年研究计划将集中在科学问题上
这一贡献群体很难单独回答,因为说英语的人和说英语的人之间的独特伙伴关系
该地区讲法语的国家。我们计划的主要具体目标将是:1)确定一个
描述与艾滋病毒护理的连续体有关的个人和结构性障碍,从艾滋病毒检测到保留
在整个西非的护理和病毒抑制方面,2)利用我们现有的网络来建立队列
西非IeDEA艾滋病毒关键人群包括女性性工作者和男男性行为者,3)
确定非传染性疾病的负担,并评估其与艾滋病毒感染的相互作用。我们的
合作支持了世界上最强大的流行病学和临床研究基础设施之一
该区域拥有近40,000名成年人(包括883名艾滋病毒-2和843名艾滋病毒-1/2)和15,814名儿童(6,515名)的数据
在七个国家,接触艾滋病毒的儿童、接受抗逆转录病毒治疗的7041名儿童和尚未接受抗逆转录病毒药物治疗的2258名艾滋病毒携带者)
在该地区(贝宁、布基纳法索、科特迪瓦、加纳、马里、多哥和塞内加尔)。下一轮谈判将涉及
在8个国家(贝宁、布基纳法索、科特迪瓦、加纳、马里、尼日利亚、塞内加尔和
多哥)。其中,有8家诊所是新的合作中心。IeDEA西非合作项目是
在法国波尔多大学与由PACCI方案主办的区域办事处协调,
设在科特迪瓦阿比让的研究型非政府组织。这个研究团队有一个
在观察艾滋病毒研究方面的长期经验,包括在西非的大规模预期队列。
每年将按照标准化程序从关联队列中收集数据并进行合并
在波尔多的协调中心。参与中心的能力建设将包括为当地
人力资源、数据质量培训、现场技术支持和年度会议,以加强
科技网络。在这一资金周期结束时,我们打算处理主要研究
差距,包括更好地了解影响西非艾滋病毒感染者的各种共病。我们的队伍将会是
更能代表区域艾滋病毒流行情况,并将收集关键人群的重要数据以供参考
针对这些弱势群体的干预措施。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Didier Koumavi Ekouevi其他文献
Correction: SARS-CoV-2 antibody seroprevalence in Togo: a national cross-sectional household survey, May–June, 2021
- DOI:
10.1186/s12889-023-15004-3 - 发表时间:
2023-01-27 - 期刊:
- 影响因子:3.600
- 作者:
Yao Rodion Konu;Siaka Condé;Fifonsi Gbeasor-Komlanvi;Arnold Junior Sadio;Martin Kouame Tchankoni;Joel Anani;Alexandra Bitty-Anderson;Bisimwa Ruhana Mirindi;Fatoumata Binta Tidiane Diallo;Moustapha MIjiyawa;Anoumou Claver Dagnra;Didier Koumavi Ekouevi - 通讯作者:
Didier Koumavi Ekouevi
Prévalence et incidence de la dépendance à trois mois post-hospitalisation chez les personnes âgées admis en hospitalisation au Togo entre 2018 et 2020
- DOI:
10.1016/j.respe.2023.102065 - 发表时间:
2023-09-01 - 期刊:
- 影响因子:
- 作者:
Fifonsi Adjidossi Gbeasor-Komlanvi;Matthieu Yaovi Lokossou;Mofou Belo;Martin Kouame Tchankoni;Rodion Konu;Arnold Sadio;Wendpouire Ida Zida-Compaore;Benjamin Kariyiare;Didier Koumavi Ekouevi - 通讯作者:
Didier Koumavi Ekouevi
Hemoglobin phenotypes of children attending pediatric clinics in Lomé, Togo, 2022
- DOI:
10.1186/s13104-025-07150-1 - 发表时间:
2025-02-18 - 期刊:
- 影响因子:1.700
- 作者:
Yao Rodion Konu;Fiali Ayawa Lack;Oumarou I. Wone Adama;Harold Régis Kouanfack;Kokou Herbert Gounon;Kokou François Sogbo;Kodzovi Mawulé Corcellar Womey;Ounoo Elom Takassi;Maléwé Kolou;Didier Koumavi Ekouevi - 通讯作者:
Didier Koumavi Ekouevi
Prévalence de Chlamydia trachomatis , Neisseria gonorrhoeae , Treponema pallidum et du VIH chez les femmes à Kara, en 2022
沙眼衣原体、淋病奈瑟菌、梅毒螺旋体和卡拉女性 VIH,en 2022
- DOI:
- 发表时间:
2024 - 期刊:
- 影响因子:0
- 作者:
G.Y.S. Gnatou;F. Gbeasor;K. A. Afanvi;Sibabe Agoro;A. Sadio;L. Adoli;W. ZIDA;Y.R. Konu;M.K. Tchankoni;Didier Koumavi Ekouevi - 通讯作者:
Didier Koumavi Ekouevi
Didier Koumavi Ekouevi的其他文献
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{{ truncateString('Didier Koumavi Ekouevi', 18)}}的其他基金
International Epidemiology Databases to EvaluateAIDS (IeDEA) Renewal 4
用于评估艾滋病的国际流行病学数据库 (IeDEA) 更新 4
- 批准号:
10626943 - 财政年份:2006
- 资助金额:
$ 168.78万 - 项目类别: