Administrative Core

行政核心

• 批准号: 10491820
• 负责人: Tracy T Batchelor
• 金额: $ 10.67万
• 依托单位: BRIGHAM AND WOMEN'S HOSPITAL
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-09-21 至 2026-08-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10491820
• 关键词: Administrator; Adult Glioblastoma; Cancer Center; Catchment Area; Clinical; Clinical Trials; Collaborations; Communication; Communication Programs; Community Outreach; Complex; Dana-Farber Cancer Institute; Doctor of Medicine; Doctor of Philosophy; Electronic Mail; Faculty; Fostering; Funding; Funding Opportunities; General Hospitals; Genomics; Glioblastoma; Glioma; Goals; Grant; Hospitals; Human Resources; Image; Infrastructure; Institution; Leadership; Massachusetts; Medical; Mentorship; Monitor; Parents; Patients; Pharmacology; Pilot Projects; Principal Investigator; Research Personnel; Research Project Grants; Resources; SECTM1 gene; Scientist; Series; Site; Specialist; Structure; Students; Therapeutic; Training; Universities; Woman; Work; base; career development; community engagement; diversity and inclusion; drug development; experience; industry partner; inter-institutional; meetings; multidisciplinary; new therapeutic target; programs; ranpirnase; recruit; research and development; response; translational scientist

In response to a Funding Opportunity Announcement for multi-institutional teams to form a Glioblastoma Therapeutics Network (GTN) basic scientists and clinical/translational investigators from three institutions in the Dana-Farber/Harvard Cancer Center have joined forces with their counterparts in the Stanford Cancer Center to create the “Harvard/Stanford GTN”. The GTN study plan features three Projects an Administrative Core, a Pharmacological and Genomic Imaging Core and a proposed Network Coordinating Center (NCC). The Administrative Core will be based at Brigham and Women’s Hospital, the parent organization for the Harvard/Stanford GTN, and will serve as the coordinating center and hub for the four institutions comprising the program and all interactions with existing P30-supported resources for clinical trials. The core will coordinate internal and external components of this complex structure to foster and support multi-project, inter-disciplinary, and inter-institutional drug development research in adult glioblastoma. Core personnel include one GTN Principal Investigator, three Site Leads at the Harvard/Stanford GTN institutions, two scientific co-administrators, a program coordinator, two grants specialists, and an administrative assistant. There are five Specific Aims in the Administrative Core. In the First Aim, the core will develop and engage a multidisciplinary Internal Advisory Board to provide critical oversight of the overall Harvard/Stanford GTN program. In the Second Aim, the core will organize regular meetings of key stakeholders to foster collaboration, troubleshooting, and monitoring of progress. In the Third and Fourth Aims, the core will maintain a trans-institutional program for regular, internal and external electronic communication among Harvard/Stanford project and core co-leads, clinical trialists, the GTN Steering Committee, the NCC, NCI program officials, and industry partners. In the Fifth Aim, the core will engage with institutional leaders at Harvard and Stanford to promote diversity and inclusion throughout the Harvard/Stanford GTN program. The Administrative Core Leader, Tracy Batchelor, M.D., will serve as the overall Principal Investigator of the Harvard/Stanford GTN program with able assistance from Site Leads at Dana-Farber Cancer Institute (Patrick Wen, M.D.), Massachusetts General Hospital (Isabel Arrillaga, M.D., Ph.D.), and Stanford University (Michelle Monje, M.D., Ph.D.). This trans-institutional administrative team at Dana-Farber/Harvard Cancer Center and Stanford Cancer Center have worked together effectively on other multi-center, multi-project, NCI-sponsored glioma research projects.

回应多机构团队成立胶质母细胞瘤的资助机会宣布 治疗网络(GTN)来自三个机构的基础科学家和临床/翻译研究人员 达纳-法伯/哈佛癌症中心已经与斯坦福癌症研究中心的同行联手 中心创建了“哈佛/斯坦福GTN”。GTN研究计划包括三个项目和 管理核心、药理学和基因组成像核心和建议的网络 协调中心(NCC)。行政核心将设在布里格姆妇女医院， 哈佛/斯坦福GTN的上级组织，并将作为 组成该计划的四个机构以及与现有P30支持的临床资源的所有互动 审判。核心将协调这一复杂结构的内部和外部组成部分，以促进和支持 成人胶质母细胞瘤的多项目、跨学科和跨机构药物开发研究。堆芯 人员包括一名GTN首席调查员，哈佛/斯坦福GTN机构的三名现场负责人， 两名科学协管人、一名项目协调员、两名拨款专家和一名行政助理。 行政核心有五个具体目标。在第一个目标中，核心将开发和参与 多学科内部咨询委员会将对整个哈佛/斯坦福GTN提供严格监督 程序。在第二个目标中，核心将组织主要利益攸关方的定期会议，以促进 协作、故障排除和进度监控。在第三和第四个目标中，核心将保持 跨机构的定期、内部和外部电子通信方案 哈佛/斯坦福项目和核心联合领导、临床试验、GTN指导委员会、NCC、NCI 计划官员和行业合作伙伴。在第五个目标中，核心将与机构领导人在 哈佛和斯坦福在整个哈佛/斯坦福GTN项目中促进多样性和包容性。这个 行政核心领导，医学博士Tracy Batchelor将担任 哈佛/斯坦福GTN项目，得到Dana-Farber癌症研究所(Patrick)Site Leads的有力帮助 马萨诸塞州总医院(Isabel Arrillaga，医学博士)和斯坦福大学(Michelle) Monje，医学博士，博士)。达纳-法伯/哈佛癌症中心的跨机构管理团队 斯坦福癌症中心在其他多中心、多项目、NCI赞助的项目上有效地合作 神经胶质瘤研究项目。