Administrative Core (AC)

项目摘要/摘要 行政核心(AC)的总体目标是提供一个结构和一套活动，以 整合科学和科学家的综合Omics中心以促进神经生物学 了解阿片成瘾(ICAN)以促进对阿片成瘾生物驱动因素的突破性发现 阿片成瘾(OA)。科学家、组学数据、队列、物种和分析的多样性是巨大的 ICAN的优势。这种多样性也是一个挑战。我们将通过以下方式系统地应对这一挑战 频繁的跨ICAN交互、共享里程碑设置和评估、使用集中计算和 协同核心(SYNC)中的协议开发，并利用协作技术。交流电源，输入 与同步相结合，将从多样性中创造协同效应，共同实现ICAN目标，丰富 社区。咨询委员会有以下具体目标： 目标1.设立中心指导委员会，作为跨美洲国家间交流的渠道，并 治理。 目标2.设立外部咨询委员会，积极联系外部专门知识和 加强ICAN的科学性和影响力的财团。 目标3.为ICAN设定年度里程碑并评估绩效，以及每个项目和 核心。 目标4.利用共享技术加强调查人员的互动和记录。 目标5.向社区提供教育和宣传，促进国际社区委员会作为国家 资源。

PROJECT SUMMARY/ABSTRACT The overall goal of the Administrative Core (AC) is to provide a structure and set of activities that integrates the science and scientists of the Integrative Omics Center for Accelerating Neurobiological Understanding of Opioid Addiction (ICAN) to facilitate breakthrough discoveries in the biological drivers of opioid addiction (OA). The diversity of scientists, omics data, cohorts, species, and analyses are substantial strengths of ICAN. That diversity is also a challenge. We will systematically meet this challenge through frequent cross-ICAN interaction, shared milestone setting and evaluation, use of centralized computing and protocol development in the Synergy Core (SynC), and leveraging collaboration technology. The AC, in conjunction with the SynC, will create synergy from diversity to collectively achieve ICAN aims and enrich the community. The AC has the following specific aims: Aim 1. Establish the Center Steering Committee as a conduit for cross-ICAN communication and governance. Aim 2. Establish the External Advisory Board as an active connection to external expertise and consortia to enhance the science and impact of ICAN. Aim 3. Set annual milestones and evaluate performance for ICAN, as well as for each Project and Core. Aim 4. Leverage sharing technology to enhance investigator interaction and documentation. Aim 5. Provide education and outreach to the community, facilitating ICAN’s role as a national resource.