Data Core – Improving Provider Announcement Communication Training (IMPACT)

摘要-数据核心 数据核心将集中P01计划项目研究项目的数据相关服务， “改善供应商公告沟通培训（IMPACT）”，在北卡罗来纳州大学。 IMPACT计划项目将通过开发新的 改善提供者沟通和人乳头瘤病毒（HPV）疫苗的有效策略的证据 摄取。Justin Trogdon博士和Nisha Gottfredson博士将担任Data Core的联合负责人。数据核心 其职能包括管理国家初级保健小组调查、清理和标准化有效性数据 并为随机化和分析提供统计支持。的三项具体 数据核心的目标如下。目标1是发展、监督和管理国家初级保健 团队调查数据核心将调查2，500名初级保健团队成员：1，500名HPV疫苗提供者 （医生、医生助理和执业护士）和1 000名注册护士和医疗助理 参与青少年疫苗接种。数据中心将负责协调和整合调查 跨项目使用的测量，与调查分包商合作监督调查 实施，以及管理和准备供研究项目使用的数据。目标2：促进 访问研究项目生成的大型疫苗接种数据集并使其结构标准化 随机临床试验。数据核心将成为管理、协调、存储和 分发用于评估干预影响的随机临床试验疫苗结果数据 在项目1到3之间。核心还将向项目4提供结果数据以支持预算影响 成本效益模型。目标3是为研究提供统计和方法支持 项目数据核心团队将项目研究者与适当的统计和研究设计联系起来 根据研究项目的需要，设计和咨询分析的专业知识。数据核心活动将 导致国家初级保健团队调查，高质量，标准化的数据和适当和严格的 以有效的方式进行统计分析，以提高P01计划的集体科学影响 项目数据核心通过帮助研究项目解决IMPACT计划项目主题， 在卫生保健系统的初级保健团队中建立HPV疫苗沟通干预的能力。

ABSTRACT – Data Core The Data Core will centralize data-related services across research projects for the P01 Program Project, “Improving Provider Announcement Communication Training (IMPACT),” at the University of North Carolina. The IMPACT Program Project will make a significant contribution to cancer prevention by developing new evidence on effective strategies to improve provider communication and human papillomavirus (HPV) vaccine uptake. Drs. Justin Trogdon and Nisha Gottfredson will be the co-leads of the Data Core. The Data Core’s functions include managing a national primary care team survey, cleaning and standardizing effectiveness data across research projects and providing statistical support for randomization and analysis. The three Specific Aims of the Data Core are as follows. Aim 1 is to develop, oversee, and manage the national primary care team survey. The Data Core will survey 2,500 primary care team members: 1,500 HPV vaccine providers (physicians, physician assistants, and nurse practitioners) and 1,000 registered nurses and medical assistants involved in adolescent vaccination. The Data Core will be responsible for coordinating and integrating survey measures for use across projects, collaborating with the survey subcontractor to oversee survey implementation, and managing and preparing data for use by the research projects. Aim 2 is to facilitate access to, and standardize the structure of, large vaccination datasets generated by research project randomized clinical trials. The Data Core will be a central hub for managing, harmonizing, storing, and distributing randomized clinical trial vaccine outcomes data that will be used to evaluate intervention impact across Projects 1 through 3. The Core will also provide the resulting data to Project 4 to support budget impact and cost-effectiveness modelling. Aim 3 is to provide statistical and methodological support to research projects. The Data Core team will connect project investigators with appropriate statistical and study design expertise to design and consult on analyses as needed by the research projects. The Data Core activities will result in a national primary care team survey, high-quality, standardized data and appropriate and rigorous statistical analysis in an efficient manner that will increase the collective scientific impact of the P01 Program Project. The Data Core addresses the IMPACT Program Project theme by helping the research projects to build capacity for HPV vaccine communication interventions among primary care teams in healthcare systems.