Molecular Regulation of B cells and T cells in Human SLE
人类 SLE 中 B 细胞和 T 细胞的分子调控
基本信息
- 批准号:10493525
- 负责人:
- 金额:$ 8.88万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2021
- 资助国家:美国
- 起止时间:2021-07-01 至 2024-04-30
- 项目状态:已结题
- 来源:
- 关键词:AntigensAntitumor ResponseAutoantigensAutoimmuneAutoimmune DiseasesAutoimmune ResponsesAutoimmunityB cell differentiationB-Cell DevelopmentB-LymphocytesBiological MarkersCD8-Positive T-LymphocytesCancer PatientCategoriesCell physiologyCellsChronicClinicalClinical ProtocolsClinical ResearchCollaborationsCommittee MembersComparative StudyDevelopmentDiagnosisDiseaseEffector CellEpigenetic ProcessEvolutionFundingGenetic Predisposition to DiseaseGoalsHeterogeneityHumanImmuneImmune checkpoint inhibitorImmune responseImmunologicsIndividualKnowledgeLeadLeadershipLocationLupusMaintenanceMissionMolecularOnset of illnessOutcomePD-1 blockadePathogenesisPathogenicityPathway interactionsPatientsPhysiciansPilot ProjectsPopulationProcessRegulationResourcesScientistSystemic Lupus ErythematosusT-LymphocyteTranslatingUniversitiesVirus DiseasesWorkarmautoreactive B cellbaseclinical developmentdesignepigenetic regulationepigenomeexhaustionexperienceimmunogenicimprintinnovationnoveloperationpersonalized medicineprogramsresponseself-renewalstemstem-like cell
项目摘要
Abstract
The Emory ACE Fund Management Core (EAFMC) at Emory University proposes to manage on
behalf of the ACE network two funds. The first will be the Clinical Project Fund, which will support
all of the Clinical Projects (ClinProj) within the ACE. The second will be the Collaborative
Research Fund (CRF). The CRF will provide funding support for the Collaborative Projects of the
ACE, as well as additional studies that are added for achieving the ACE research agenda. It is
estimated from the RFA that the AFMC will manage $3.2M in direct costs associated with these
projects and that these will occur through about 100 consortium agreements emanating from up
to 50 different sites. It will accomplish this through the following aims: (1) Establishing an effective
administrative structure and operating unit, (2) developing plans to effectively produce and
execute budgets and consortium agreements, (3) establish templates for the ClinProj and CRP
budget agreements, (4) develop procedures to pay invoices and resolve problems; and (5)
develop procedures for accountability, communication, and reporting to the ACE Steering
committee and NIAID.
摘要
项目成果
期刊论文数量(0)
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Ignacio E. Sanz其他文献
Ignacio E. Sanz的其他文献
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{{ truncateString('Ignacio E. Sanz', 18)}}的其他基金
Molecular Regulation of B cells and T cells in Human SLE
人类 SLE 中 B 细胞和 T 细胞的分子调控
- 批准号:
10439989 - 财政年份:2021
- 资助金额:
$ 8.88万 - 项目类别:
ACE Covid 19 Admin Supplement: Molecular Regulation of B cells and T cells in Human SLE
ACE Covid 19 管理补充:人类 SLE 中 B 细胞和 T 细胞的分子调节
- 批准号:
10456447 - 财政年份:2021
- 资助金额:
$ 8.88万 - 项目类别:
Administrative Supplement Covid19: Molecular Regulation of B cells and T cells in Human SLE
行政补充 Covid19:人类 SLE 中 B 细胞和 T 细胞的分子调控
- 批准号:
10164943 - 财政年份:2020
- 资助金额:
$ 8.88万 - 项目类别:
Molecular Regulation of B cells and T cells in Human SLE
人类 SLE 中 B 细胞和 T 细胞的分子调控
- 批准号:
10265747 - 财政年份:2020
- 资助金额:
$ 8.88万 - 项目类别:
Immune Regulation of COVID-19 Infection in Cancer and Autoimmunity
癌症和自身免疫中 COVID-19 感染的免疫调节
- 批准号:
10680628 - 财政年份:2020
- 资助金额:
$ 8.88万 - 项目类别:
Immune Regulation of COVID-19 Infection in Cancer and Autoimmunity
癌症和自身免疫中 COVID-19 感染的免疫调节
- 批准号:
10680631 - 财政年份:2020
- 资助金额:
$ 8.88万 - 项目类别:
Immune Regulation of COVID-19 Infection in Cancer and Autoimmunity
癌症和自身免疫中 COVID-19 感染的免疫调节
- 批准号:
10222317 - 财政年份:2020
- 资助金额:
$ 8.88万 - 项目类别:
Regulation of Pathogenic Plasma Cells in Human SLE
人类系统性红斑狼疮致病性浆细胞的调控
- 批准号:
10187509 - 财政年份:2020
- 资助金额:
$ 8.88万 - 项目类别:
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