Administrative and Mentoring Core

摘要 行政和指导核心将管理科布雷的行政和财政方面。 核心还将支持对四名初级调查员的指导，并促进老龄问题的过渡-- 相关的Kuakini檀香山心脏计划研究成为衰老研究的资源。这一核心还将 协调Kuakini医疗中心(Kuakini)Cobre的日常管理 关于老龄化的翻译研究(Kuakini Cobre-CTRA)。管理和指导核心意志 制定有外部咨询委员会(EAC)参与的强有力的指导计划 以及一项试点项目计划，鼓励扩大与老龄化相关的调查。行政部门 指导核心将协调指导四名初级调查人员所需的所有资源，并支持 创建一个多方面的研究中心，其中包括翻译研究的强大组成部分。 这个核心的总体目标是建立一个能够改善当前和未来的老龄化研究中心 研究竞争力，多样化研究广度和跨学科范围，老龄化 夏威夷的研究。 这将通过以下具体目标来实现： 具体目标1：向Kuakini Cobre-CTRA提供行政和财政支助。这个 行政和指导核心将由Kuakini Cobre的PI Bradley Willcox博士指导- CTRA。他将得到诊所副主任和副主任的协助。 翻译核心。他还将得到三名现任Cobre PI的建议，他们在以下方面具有丰富的经验 科布雷行政部门(内部咨询委员会)。选管会将同时担当谘询和评估的角色。 科布雷的角色。 行政和指导核心的一个主要目标将是协调 由Kuakini Cobre-CTRA支持的资源，包括对初级调查员、东非共同体、 导师、访问科学家和共享队列资源，用于优化跨学科翻译 关于夏威夷老龄化的研究。 具体目标2：管理和协调每个初级调查员的个人指导计划。 行政和指导核心将为四名初级调查员制定详细的指导计划 这解决了在我们偏远地区指导初级教员的挑战。的主要元素是 指导计划是每个初级调查员的指导团队。这包括一名当地的主要导师 谁对这个项目有见识 ，至少另有一位外部导师有很大的互补性 专家，以及Cobre Pi，副主任和副主任。它的作用将是 管理和指导核心，以协调Cobre的相关方面，以实现以下重点 初级调查员。 具体目标3：建立将刺激和提供校外活动的试点项目机会 资助关于老龄化的高质量研究提案。试点项目机会的目的是 主要是支持早期研究人员，帮助他们为与老龄化有关的赠款生成初步数据 申请。其次，我们将为更成熟的研究人员提供支持，他们需要适度的 为成功筹资或获得与老龄有关的试点数据提供已提交赠款的额外援助 研究。为此，我们将建立一个严格和公平的审查程序，以选择最令人兴奋的研究 提案和最有可能成功的候选人。

ABSTRACT The Administrative and Mentoring Core will manage the administrative and fiscal aspects of the COBRE. The Core will also support mentoring of the four Junior Investigators and facilitate the transition of the aging- related Kuakini Honolulu Heart Program studies into a resource for aging research. This Core will also coordinate the day-to-day management of the Kuakini Medical Center (Kuakini) COBRE-Center for Translational Research on Aging (Kuakini COBRE-CTRA). The Administrative and Mentoring Core will develop a strong mentoring plan that will involve the participation of the External Advisory Committee (EAC) and a Pilot Project Program to encourage the expansion of aging-related investigations. The Administrative and Mentoring Core will coordinate all resources required to mentor four Junior Investigators and to support the creation of a multi-faceted research center that includes a strong component of translational research. The overall goal of this Core is to build an aging research center that will improve current and future research competitiveness, and diversify the research breadth and trans-disciplinary scope, of aging research in Hawaii. This will be accomplished through the following specific aims: Specific Aim 1: Provide administrative and fiscal support for the Kuakini COBRE-CTRA. The Administrative & Mentoring Core will be directed by Dr. Bradley Willcox, the PI of the Kuakini COBRE- CTRA. He will be assisted by the Deputy Director as well as the Associate Directors of the Clinical Translational Core. He will also be advised by three current COBRE PIs who have substantial experience in COBRE administration (Internal Advisory Committee). The EAC will play both advisory and assessment roles for the COBRE. A major goal of the Administrative and Mentoring Core will be to coordinate the resources supported by the Kuakini COBRE-CTRA, including the support for Junior Investigators, EAC, mentors, visiting scientists, and shared cohort resources, for optimizing interdisciplinary translational research on aging in Hawaii. Specific Aim 2: Manage and coordinate an individual mentoring plan for each Junior Investigator. The Administrative & Mentoring Core will develop a detailed mentoring plan for the four Junior Investigators that addresses the challenge of mentoring junior faculty in our remote location. The primary element of the mentoring plan is the Mentoring Team for each Junior Investigator. This includes a local primary mentor who is knowledgeable in the project , at least one other external mentor with substantial complementary expertise, as well as the COBRE PI, Deputy Director, and Associate Directors. It will be the role of the Administrative and Mentoring Core to coordinate relevant aspects of the COBRE for the focused benefit of the Junior Investigators. Specific Aim 3: Establish a Pilot Project Opportunity that will stimulate and provide extramural funding of high quality research proposals on aging. The purpose of the Pilot Project Opportunity is primarily to support early stage researchers to help them generate preliminary data for aging-related grant applications. Secondarily, we will provide support to more established researchers who require modest additional assistance to bring a submitted grant to successful funding or to obtain pilot data for aging-related research. For this aim, we will create a rigorous and fair review process to select the most exciting research proposals and the candidates most likely to succeed.