Administrative and Mentoring Core

摘要 行政和指导核心将管理 COBRE 的行政和财务方面。 该核心还将支持对四名初级研究员的指导，并促进老龄化的过渡 相关 Kuakini 檀香山心脏计划研究成为衰老研究资源。该核心还将 协调 Kuakini 医疗中心 (Kuakini) COBRE 中心的日常管理 衰老转化研究（Kuakini COBRE-CTRA）。行政和指导核心将 制定一个强有力的指导计划，其中包括外部咨询委员会 (EAC) 的参与 以及鼓励扩大与老龄化相关的调查的试点项目计划。行政部门 指导核心将协调指导四名初级研究员并支持所需的所有资源 创建一个多方面的研究中心，其中包括转化研究的强大组成部分。 该核心的总体目标是建立一个老龄化研究中心，以改善当前和未来 研究竞争力，并使老龄化研究广度和跨学科范围多样化 在夏威夷进行研究。 这将通过以下具体目标来实现： 具体目标 1：为 Kuakini COBRE-CTRA 提供行政和财政支持。的 行政和指导核心将由 Kuakini COBRE 的 PI Bradley Willcox 博士指导 CTRA。他将得到临床副主任和副主任的协助 翻译核心。他还将得到三位现任 COBRE PI 的建议，他们在以下方面拥有丰富的经验： COBRE 管理（内部咨询委员会）。选管会将发挥咨询和评估作用 COBRE 的角色。 行政和指导核心的一个主要目标是协调 Kuakini COBRE-CTRA 支持的资源，包括对初级调查员、EAC、 导师、访问科学家和共享队列资源，以优化跨学科转化 夏威夷老龄化研究。 具体目标 2：管理和协调每位初级研究员的个人指导计划。 行政和指导核心将为四名初级研究员制定详细的指导计划 这解决了在我们偏远地区指导初级教师的挑战。的主要元素 指导计划是每个初级研究员的指导团队。这包括当地的主要导师 谁对项目有了解 ，至少一位具有实质性互补性的外部导师 专业知识，以及 COBRE PI、副总监和副总监。这将是 行政和指导核心协调 COBRE 的相关方面，以实现以下目标的重点利益： 初级调查员。 具体目标 3：建立一个试点项目机会，以刺激和提供校外活动 资助有关老龄化的高质量研究提案。试点项目机会的目的是 主要是为了支持早期研究人员，帮助他们生成与老龄化相关的资助的初步数据 应用程序。其次，我们将为需要适度支持的更成熟的研究人员提供支持 为成功资助所提交的赠款或获取与老龄化相关的试点数据提供额外援助 研究。为此，我们将创建严格且公平的审查流程来选择最令人兴奋的研究 提案和最有可能成功的候选人。

ABSTRACT The Administrative and Mentoring Core will manage the administrative and fiscal aspects of the COBRE. The Core will also support mentoring of the four Junior Investigators and facilitate the transition of the aging- related Kuakini Honolulu Heart Program studies into a resource for aging research. This Core will also coordinate the day-to-day management of the Kuakini Medical Center (Kuakini) COBRE-Center for Translational Research on Aging (Kuakini COBRE-CTRA). The Administrative and Mentoring Core will develop a strong mentoring plan that will involve the participation of the External Advisory Committee (EAC) and a Pilot Project Program to encourage the expansion of aging-related investigations. The Administrative and Mentoring Core will coordinate all resources required to mentor four Junior Investigators and to support the creation of a multi-faceted research center that includes a strong component of translational research. The overall goal of this Core is to build an aging research center that will improve current and future research competitiveness, and diversify the research breadth and trans-disciplinary scope, of aging research in Hawaii. This will be accomplished through the following specific aims: Specific Aim 1: Provide administrative and fiscal support for the Kuakini COBRE-CTRA. The Administrative & Mentoring Core will be directed by Dr. Bradley Willcox, the PI of the Kuakini COBRE- CTRA. He will be assisted by the Deputy Director as well as the Associate Directors of the Clinical Translational Core. He will also be advised by three current COBRE PIs who have substantial experience in COBRE administration (Internal Advisory Committee). The EAC will play both advisory and assessment roles for the COBRE. A major goal of the Administrative and Mentoring Core will be to coordinate the resources supported by the Kuakini COBRE-CTRA, including the support for Junior Investigators, EAC, mentors, visiting scientists, and shared cohort resources, for optimizing interdisciplinary translational research on aging in Hawaii. Specific Aim 2: Manage and coordinate an individual mentoring plan for each Junior Investigator. The Administrative & Mentoring Core will develop a detailed mentoring plan for the four Junior Investigators that addresses the challenge of mentoring junior faculty in our remote location. The primary element of the mentoring plan is the Mentoring Team for each Junior Investigator. This includes a local primary mentor who is knowledgeable in the project , at least one other external mentor with substantial complementary expertise, as well as the COBRE PI, Deputy Director, and Associate Directors. It will be the role of the Administrative and Mentoring Core to coordinate relevant aspects of the COBRE for the focused benefit of the Junior Investigators. Specific Aim 3: Establish a Pilot Project Opportunity that will stimulate and provide extramural funding of high quality research proposals on aging. The purpose of the Pilot Project Opportunity is primarily to support early stage researchers to help them generate preliminary data for aging-related grant applications. Secondarily, we will provide support to more established researchers who require modest additional assistance to bring a submitted grant to successful funding or to obtain pilot data for aging-related research. For this aim, we will create a rigorous and fair review process to select the most exciting research proposals and the candidates most likely to succeed.