Administrative and Mentoring Core

摘要 行政和指导核心将管理COBRE的行政和财务方面。 核心小组还将支持对四名初级调查员的指导，并促进老龄化的过渡- 相关的Kuakini檀香山心脏计划研究成为老龄化研究的资源。该核心还将 协调Kuakini医疗中心（Kuakini）COBRE-Center的日常管理， 衰老转化研究（Kuakini COBRE-CTRA）。管理和指导核心将 制定强有力的指导计划，其中包括外部咨询委员会（EAC）的参与 以及一个试点项目方案，以鼓励扩大与老龄化有关的调查。行政 指导核心将协调指导四名初级研究者所需的所有资源，并支持 创建一个多方面的研究中心，其中包括翻译研究的强大组成部分。 该核心的总体目标是建立一个老龄化研究中心， 研究竞争力，多样化的研究广度和跨学科的范围，老龄化 在夏威夷做研究 这将通过以下具体目标来实现： 具体目标1：为Kuakini COBRE-CTRA提供行政和财政支助。的 管理和指导核心将由Kuakini COBRE的PI布拉德利威尔考克斯博士指导- Ctra.他将得到副主任以及临床研究中心副主任的协助。 翻译核心他还将听取三名现任COBRE PI的建议，这些PI在以下方面具有丰富的经验： COBRE管理（内部咨询委员会）。选管会将发挥咨询和评估作用， COBRE的角色 行政和指导核心的一个主要目标是协调 Kuakini COBRE-CTRA支持的资源，包括对初级研究员、EAC的支持， 导师，访问科学家和共享的队列资源，用于优化跨学科翻译 在夏威夷进行的老龄化研究。 具体目标2：管理和协调每个初级研究员的个人指导计划。 行政和指导核心将为四名初级调查员制定详细的指导计划 解决了在我们偏远地区指导初级教师的挑战。的主要元素 指导计划是每个初级调查员的指导小组。其中包括一名当地的初级导师 他对这个项目很了解 ，至少有一名其他外部导师， 专业知识，以及COBRE PI，副主任和助理主任。这将是作用的 行政和指导核心协调COBRE的相关方面，重点关注以下利益： 初级调查员。 具体目标3：建立一个试点项目的机会，将刺激和提供校外 资助高质量的老龄化研究提案。试点项目机会的目的是 主要是支持早期研究人员，帮助他们为与衰老相关的补助金提供初步数据 应用.其次，我们将为那些需要适度研究的更成熟的研究人员提供支持。 提供额外援助，使提交的赠款成功获得资金，或获得与老龄化有关的试验数据 research.为此，我们将建立一个严格和公平的审查程序，以选择最令人兴奋的研究 候选人和候选人最有可能成功。

ABSTRACT The Administrative and Mentoring Core will manage the administrative and fiscal aspects of the COBRE. The Core will also support mentoring of the four Junior Investigators and facilitate the transition of the aging- related Kuakini Honolulu Heart Program studies into a resource for aging research. This Core will also coordinate the day-to-day management of the Kuakini Medical Center (Kuakini) COBRE-Center for Translational Research on Aging (Kuakini COBRE-CTRA). The Administrative and Mentoring Core will develop a strong mentoring plan that will involve the participation of the External Advisory Committee (EAC) and a Pilot Project Program to encourage the expansion of aging-related investigations. The Administrative and Mentoring Core will coordinate all resources required to mentor four Junior Investigators and to support the creation of a multi-faceted research center that includes a strong component of translational research. The overall goal of this Core is to build an aging research center that will improve current and future research competitiveness, and diversify the research breadth and trans-disciplinary scope, of aging research in Hawaii. This will be accomplished through the following specific aims: Specific Aim 1: Provide administrative and fiscal support for the Kuakini COBRE-CTRA. The Administrative & Mentoring Core will be directed by Dr. Bradley Willcox, the PI of the Kuakini COBRE- CTRA. He will be assisted by the Deputy Director as well as the Associate Directors of the Clinical Translational Core. He will also be advised by three current COBRE PIs who have substantial experience in COBRE administration (Internal Advisory Committee). The EAC will play both advisory and assessment roles for the COBRE. A major goal of the Administrative and Mentoring Core will be to coordinate the resources supported by the Kuakini COBRE-CTRA, including the support for Junior Investigators, EAC, mentors, visiting scientists, and shared cohort resources, for optimizing interdisciplinary translational research on aging in Hawaii. Specific Aim 2: Manage and coordinate an individual mentoring plan for each Junior Investigator. The Administrative & Mentoring Core will develop a detailed mentoring plan for the four Junior Investigators that addresses the challenge of mentoring junior faculty in our remote location. The primary element of the mentoring plan is the Mentoring Team for each Junior Investigator. This includes a local primary mentor who is knowledgeable in the project , at least one other external mentor with substantial complementary expertise, as well as the COBRE PI, Deputy Director, and Associate Directors. It will be the role of the Administrative and Mentoring Core to coordinate relevant aspects of the COBRE for the focused benefit of the Junior Investigators. Specific Aim 3: Establish a Pilot Project Opportunity that will stimulate and provide extramural funding of high quality research proposals on aging. The purpose of the Pilot Project Opportunity is primarily to support early stage researchers to help them generate preliminary data for aging-related grant applications. Secondarily, we will provide support to more established researchers who require modest additional assistance to bring a submitted grant to successful funding or to obtain pilot data for aging-related research. For this aim, we will create a rigorous and fair review process to select the most exciting research proposals and the candidates most likely to succeed.