RFA-CK-22-003, Emerging Infections Sentinel Networks (EISN) Research - 2022

项目摘要 1995年，在医学研究所的报告“新发感染”之后，为了回应 疾控中心加强监控、紧急身份证网的战略计划是 已经成立了。紧急身份证网的目标是解决新出现的传染性疾病的威胁 通过评估疾病患病率、风险因素和急性呼吸道感染的管理做法 社区在多样化和服务不足的患者群体中的陈述 向美国急救部门(EDS)提交报告。美国疾病控制与预防中心的一笔合作赠款为 在过去的25年里一直在使用网络。由于能够前瞻性地收集临床数据和 来自社区的急病患者的24小时现场实验室分析样本， 紧急ID网已经能够产生翻译研究，这对 医生实践和知情的公共卫生政策。研究网络展示了它的 在新冠肺炎大流行期间成功应对紧急公共卫生威胁的能力 通过快速实施20点和16点ED患者公共卫生监测项目 一线卫生保健人员的护理相关感染风险和疫苗有效性。 许多同行评议的出版物是由紧急身份证网研究产生的， 包括在影响较大的期刊上，如《新英格兰医学杂志》、《医学杂志》 美国医学会，临床传染病，新发传染病， 和《急诊医学年鉴》。 未来5年紧急身份证网的目标是：1)识别新出现的感染 以及这些疾病影响美国ED患者的风险因素，包括服务不足的患者 小组；2)利用紧急ID网的调查结果创建新的协作以开发和 改进诊断测试、治疗和疫苗；以及3)在全国范围内传播结果 医学会议，在影响较大的期刊上，以及关于传染病、公共卫生和 急诊医学社交媒体渠道，告知治疗和公共卫生政策，以及 教育公众。未来5年对紧急身份证网的支持将确保 网络可以继续回答有关新出现的感染和相关领域的新问题 高度重视公共卫生。

Project Summary In 1995, following the Institute of Medicine’s report, “Emerging Infections,” and in response to the CDC’s strategic plan to enhance surveillance, EMERGEncy ID NET was established. EMERGEncy ID NET's goal was to address the threat of emerging infectious diseases by assessing disease prevalence, risk factors, and management practices for acute presentations from the community among a diverse and underserved population of patients presenting to US emergency departments (EDs). A CDC cooperative grant has funded the network for the last 25 years. Due to the ability to prospectively collect clinical data and specimens for on-site laboratory analysis 24/7 from acutely ill patients from the community, EMERGEncy ID NET has been able to produce translational research that has impacted physician practices and informed public health policy. The research network demonstrated its capability to successfully address an urgent public health threat during the COVID-19 pandemic by rapidly implementing 20-site and 16-site public health surveillance projects of ED patient care-related infection risk and vaccine effectiveness among frontline health care personnel. Numerous peer-reviewed publications have resulted from EMERGEncy ID NET research, including in high-impact journals such as The New England Journal of Medicine, the Journal of the American Medical Association, Clinical Infectious Diseases, Emerging Infectious Diseases, and Annals of Emergency Medicine. Aims of EMERGEncy ID NET for the next 5 years are to: 1) identify emerging infections and risk factors for these conditions affecting US ED patients, including among underserved groups; 2) leverage EMERGEncy ID NET’s findings to create new collaborations to develop and improve diagnostic tests, treatments, and vaccines; and 3) disseminate results at national medical conferences, in high-impact journals, and on infectious diseases, public health, and emergency medicine social media outlets to inform treatment and public health policy, and educate the public. Support of EMERGEncy ID NET for the next 5 years will ensure that the network can continue to answer new questions about emerging infections and related areas of high public health priority.