RFA-CK-22-003, Emerging Infections Sentinel Networks (EISN) Research - 2022

项目摘要 1995年，在医学研究所的报告“新发感染”之后， 疾病预防控制中心的战略计划，以加强监测，紧急身份证网络是 确立了习EMERGEncy ID NET的目标是解决新出现的传染性疾病的威胁， 通过评估疾病患病率、风险因素和急性 来自社区的介绍，其中包括多样化和服务不足的患者人群 向美国紧急部门（ED）提交。疾病预防控制中心的合作赠款资助了 网络过去25年由于能够前瞻性地收集临床数据， 来自社区的急性病患者的样本用于现场实验室分析， EMERGEncy ID NET已经能够进行转化研究， 医生的做法和知情的公共卫生政策。研究网络显示， 在COVID-19大流行期间成功应对紧急公共卫生威胁的能力 通过快速实施20点和16点艾德病人公共卫生监测项目 前线医护人员的护理相关感染风险和疫苗有效性。 许多同行评审的出版物都来自EMERGEncy ID NET研究， 包括在高影响力的期刊，如新英格兰医学杂志， 美国医学会，临床传染病，新发传染病， 和《急诊医学年鉴》 EMERGEncy ID NET未来5年的目标是：1）识别新出现的感染 以及影响美国艾德患者的这些疾病的风险因素，包括服务不足的患者 2）利用EMERGEncy ID NET的发现来创建新的合作， 改进诊断测试、治疗和疫苗; 3）在国家一级传播结果 医学会议，在高影响力的期刊，以及传染病，公共卫生， 紧急医学社交媒体渠道，以告知治疗和公共卫生政策，以及 教育公众。在未来5年内，对EMERGEncy ID NET的支持将确保 网络可以继续回答有关新出现的感染和相关领域的新问题， 高度重视公共卫生。

Project Summary In 1995, following the Institute of Medicine’s report, “Emerging Infections,” and in response to the CDC’s strategic plan to enhance surveillance, EMERGEncy ID NET was established. EMERGEncy ID NET's goal was to address the threat of emerging infectious diseases by assessing disease prevalence, risk factors, and management practices for acute presentations from the community among a diverse and underserved population of patients presenting to US emergency departments (EDs). A CDC cooperative grant has funded the network for the last 25 years. Due to the ability to prospectively collect clinical data and specimens for on-site laboratory analysis 24/7 from acutely ill patients from the community, EMERGEncy ID NET has been able to produce translational research that has impacted physician practices and informed public health policy. The research network demonstrated its capability to successfully address an urgent public health threat during the COVID-19 pandemic by rapidly implementing 20-site and 16-site public health surveillance projects of ED patient care-related infection risk and vaccine effectiveness among frontline health care personnel. Numerous peer-reviewed publications have resulted from EMERGEncy ID NET research, including in high-impact journals such as The New England Journal of Medicine, the Journal of the American Medical Association, Clinical Infectious Diseases, Emerging Infectious Diseases, and Annals of Emergency Medicine. Aims of EMERGEncy ID NET for the next 5 years are to: 1) identify emerging infections and risk factors for these conditions affecting US ED patients, including among underserved groups; 2) leverage EMERGEncy ID NET’s findings to create new collaborations to develop and improve diagnostic tests, treatments, and vaccines; and 3) disseminate results at national medical conferences, in high-impact journals, and on infectious diseases, public health, and emergency medicine social media outlets to inform treatment and public health policy, and educate the public. Support of EMERGEncy ID NET for the next 5 years will ensure that the network can continue to answer new questions about emerging infections and related areas of high public health priority.