2022 Quantitative Genetics and Genomics Gordon Research Conference and Seminar

项目摘要 申请寻求对戈登研究会议和戈登研究研讨会的部分支持 数量遗传学和基因组学将于2023年2月11日至17日在加利福尼亚州文图拉举行。的副标题 这次会议的主题是“利用高通量的表型技术来研究复杂的性状”。复合体 疾病(如心血管疾病)和复杂或数量性状(如肥胖)非常重要 为人类健康干杯。在过去的十年里，对这些疾病的研究发生了一场革命，原因是 DNA变异基因分型、基因组测序和其他“组学”技术的可用性。这场革命是 继续使用大量的数据集，如英国生物库和美国的等价物 100万人都有健康记录和推测的基因组序列。从以下方面提取最大的知识 这样的数据具有挑战性，本次会议将听取关于这一主题的最新研究。成果来自于 这项研究包括新的药物靶点和支持个性化药物的信息。 会议和研讨会的总体目标是聚集在量化领域工作的科学家。 遗传学和基因组学交流该领域最新成果的信息并讨论其影响 这些结果。通过创造一个网络环境，这次会议将促进交流 在该领域的科学家之间，鼓励参与者之间的新合作，并建立一个社区 对于早期职业科学家来说。从国立卫生研究院寻求的资金是为了支持年轻科学家参加研讨会 通过帮助他们支付旅费和注册费来帮助他们参加会议。

Project Summary The application seeks partial support for the Gordon Research Conference and Gordon Research Seminar on Quantitative Genetics and Genomics to be held in Ventura, California on February 11-17, 2023. The subtitle of the conference is “Leveraging high-throughput phenotyping techniques to study complex traits”. Complex diseases (e.g. cardiovascular disease) and complex or quantitative traits (e.g. obesity) are of great importance to human health. Over the last decade there has been a revolution in research on these diseases due to availability of DNA variant genotyping, genome sequencing and other “omics” technologies. This revolution is continuing with the availability of enormous datasets such as the UK biobank and USA equivalent with 1,000,000 people all with health records and imputed genome sequence. Extracting maximum knowledge from such data is challenging and this conference will hear of the latest research on this topic. The outcomes from this research include new drug targets and information to support personalised medicine. The overall aim of the conference and seminar is to bring together scientists working in the field of quantitative genetics and genomics to exchange information on the latest results in the field and to discuss the implications of these results. By creating an environment for networking, this conference will promote communication between scientists in the field, encourage new collaborations among those attending, and build a community for early career scientists. The funding sought from NIH is to support young scientists to attend the seminar and conference by assisting them with travel and registration costs.