权益分类	功能权益	普通用户	{{item.name}}会员
{{category.name}}	{{benefitItem.name}}

Testing the Efficacy of A Scalable, Telephone-Delivered, Guided Imagery Tobacco Cessation Intervention

测试可扩展、电话传递、引导图像戒烟干预措施的效果

基本信息

批准号：
10537270
负责人：
JUDITH SARAH GORDON
金额：
$ 13.22万
依托单位：
UNIVERSITY OF ARIZONA
依托单位国家：
美国
项目类别：
财政年份：
2021
资助国家：
美国
起止时间：
2021-09-27 至 2026-08-31
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10537270
关键词：
Abstinence Accounting Address Adherence Adult American Arizona Behavior Control Behavior Therapy Behavioral Biochemical Bupropion Cause of Death Cessation of life Clinical Collaborations Consumer Satisfaction Data Dependence Disease Dose Electronic cigarette Enrollment Ethnic Origin Exposure to Feasibility Studies Goals Guam Guided imagery Image Individual Integrative Medicine Internet Intervention Interview Location Measures Methods Mind-Body Intervention Modeling Monitor Motivation National Center for Complementary and Integrative Health New York Outcome Participant Patient Recruitments Patient Self-Report Persons Population Population Heterogeneity Prevalence Procedures Protocols documentation Psyche structure Public Health Puerto Rico Race Randomized Randomized Controlled Trials Reporting Sample Size Smoke Smoker Smoking Smoking Cessation Intervention Standardization Subgroup Surveys Techniques Technology Telephone Time Tobacco Tobacco Use Cessation Tobacco use Training United States Universities Visualization West Virginia aged behavior change cigarette smoke cigarette smoking design disorder later incidence prevention disorder risk efficacy clinical trial efficacy testing evidence base experience feasibility trial follow up assessment follow-up improved innovation intervention effect multisensory nicotine replacement nicotine use novel novel strategies patient engagement primary outcome programs quitline recruit reduce tobacco use response sex skills smoking abstinence smoking cessation telephone delivery telephone-based therapeutically effective tobacco cessation intervention tobacco user tool usability

项目摘要

ABSTRACT Cigarette smoking is the leading cause of death accounting for more than 480,000 deaths each year, and 16 million Americans suffer from one or more diseases caused by smoking. Cessation can significantly reduce the risk of disease even for those who have smoked for decades. Interventions using a combination of behavioral approaches that focus on maintaining smokers' motivation to quit, providing specific techniques for quitting and relapse prevention, and using Nicotine Replacement Therapy (NRT) are effective at helping tobacco users quit. However, standard behavioral treatment may not appeal to, or be effective for, some smokers and novel approaches are needed to assist these individuals. Guided Imagery (GI) is a form of mind-body therapy that involves controlled, multi-sensory visualization of specific mental images. GI is an effective therapeutic tool to change behaviors including tobacco use. Multiple studies have shown that exposure to GI results in significantly increased abstinence rates compared to controls or those taking bupropion. A large proportion of the U.S. population uses integrative health approaches. A GI tobacco cessation intervention could appeal to smokers not interested in using a behavioral approach. Although GI is an effective tool for smoking cessation, the mode of delivery has generally been in person, limiting dissemination to large populations. Systematic and meta-analytic reviews have shown that telephone quitlines are a highly scalable way to help individuals quit smoking. Quitlines are available in all 50 U.S. states, Puerto Rico and Guam. The proposed project is highly responsive to PAR-20- 154 by delivering a GI intervention via telephone which is highly scalable and could greatly increase the reach and accessibility of an effective GI smoking cessation intervention. We recently completed a randomized feasibility trial of the Be Smoke Free program. Although not powered to determine efficacy, the intervention showed promise in helping participants to quit and showed high consumer satisfaction. We developed procedures for recruiting participants and surpassed our recruitment goals. We had >90% retention at 8-weeks and >80% at 6-months. We also found high levels of adherence. The results of this randomized feasibility study indicate that a fully powered study of a GI tobacco cessation intervention delivered via telephone is warranted. Therefore, the objective of this R01 application is to conduct a randomized controlled trial to test the efficacy of the Be Smoke Free, telephone-based, GI intervention (IC) for smoking cessation compared to active behavioral control (CC). The study will recruit 1,200 diverse smokers from three states, Arizona, New York, and West Virginia to increase generalizability. Participants will be randomly assigned to receive either the IC or CC delivered by telephone by University of Arizona study coaches and will be assessed at 3- and 6-months post-enrollment by study staff. The primary outcome is biochemically verified 7-day point prevalence abstinence at 6 months. This innovative and rigorously designed project conducted by an experienced team has the potential to improve public health through the delivery of an innovative integrative GI intervention via telephone.

摘要