High School Student NeuroResearch Program (HSNRP)

摘要 亚利桑那大学（UA）高中学生神经研究计划（HSNRP）介绍，培训和培养 一个不断增长的管道不同亚利桑那州高中学生和进步的本科生，大多数代表不足- 艾德帮助弱势少数民族进行关于正常和异常神经系统的基础、转化和临床研究， 神经系统疾病和中风，并鼓励先进的研究经验和健康/医学/科学事业。 我们正在利用强大的基础设施，招聘策略，教师导师的参与，以及优秀的实习生 我们长期以来联邦资助的多学科弱势高中生，本科生， 以及医学生暑期研究项目和全年丰富活动。14 -16全日制8-12周 夏季高中和4-6名本科生每年在未来5年将提供一个扩大菜单， 密切指导神经研究（NR）的经验。为了在管道中保留，选择HSNRP受训人员将获得- 更先进的NR。学员将被纳入一个创新的，以调查为基础的夏季研究所的医学， cal Ignorance（SIMI）将生物医学已知和未知与特色NR主题和导师交织在一起 “故事”，并通过全年的丰富活动保持势头。SIMI强调“翻译翻译和 科学提问”，包括对医学语言的简要介绍，研讨会，实验室/领导， 多媒体技能研讨会和实习，临床相关性，社交网络和职业咨询。一个问题- arium形成了一个可通过移动的电话访问的培训和联网平台。在各部门和专门中心内 卓越的神经科学的重点，并由经验丰富的领导团队监督，学生的研究将 包括体内、体外、原位、计算机模拟和神经生物学/疾病（包括帕金森氏症）的建模方法， 阿尔茨海默氏症，ALS，癫痫，头部创伤，脑积水，肌肉萎缩症，疼痛/成瘾，分子精神病学， 脑发育，绘图，血脑屏障/神经保护，神经影像学，神经基因组学，神经工程，深 脑刺激、脑肿瘤、脑血管疾病、中风、神经健康差异和康复。基于我们 ~29年的跟踪记录和建立访问大型游泳池的弱势亚利桑那州学生反映在~650 SIMI- 受过训练的高中生其次是许多基础/临床NR（本科生/研究生/专业生物医学- 健康事业）管道，我们希望HSNRP继续扩大网络的多样化好奇的研究人员，医生， 和其他卫生专业人员;并通过社区参与提高“神经健康”素养。正在进行的短期和 长期评价包括调查、数据库登记、后续行动和记录疗效的档案。

ABSTRACT The University of Arizona (UA) High School Student NeuroResearch Program (HSNRP) introduces, trains, and nurtures a growing pipeline of diverse Arizona high school students and progressing undergraduates, a majority of underrepresent- ed disadvantaged minorities in basic, translational, and clinical research on the normal and abnormal nervous system, neurological disorders, and stroke, and encourages advanced research experiences and health/medical/science careers. We are leveraging strong infrastructure, recruitment strategies, faculty mentor participation, and outstanding trainee productivity of our long-standing federally funded multidisciplinary disadvantaged high school student, undergraduate, and medical student summer research programs and year-round enrichment activities. Fourteen-16 full-time 8-12 week summer high school and 4-6 undergraduate trainees annually for the next 5 years will be offered an expanding menu of closely mentored NeuroResearch (NR) experiences. For retention in the pipeline, select HSNRP trainees will be reap- pointed for more advanced NR. Trainees will be integrated into an innovative, inquiry-based Summer Institute on Medi- cal Ignorance (SIMI) which interweaves biomedical Knowns and Unknowns with featured NR topics and mentor "stories" and sustains the momentum by enrichment activities year-round. SIMI emphasizes "translating translation and scientific questioning" and includes a brief Introduction to the language of medicine, seminars, laboratory/leadership/ multimedia skill workshops and practicums, clinical correlations, social networking, and career advising. A Question- arium forms a mobile phone accessible platform for training and networking. Within departments and specialized Centers of Excellence with Neuroscience emphasis and overseen by an experienced Leadership Team, student research will encompass in vivo, vitro, situ, silico, and modeling approaches to neurobiology/disorders including Parkinson's, Alzheimer's, ALS, epilepsy, head trauma, hydrocephalus, muscular dystrophy, pain/addiction, molecular psychiatry, brain development, mapping, blood-brain barrier/neuroprotection, neuroimaging, neurogenomics, neuroengineering, deep brain stimulation, brain tumors, cerebrovascular disease, stroke, neurohealth disparities, and rehabilitation. Based on our ~29-year track record and established access to large pools of disadvantaged Arizona students reflected in ~650 SIMI- trained high school students followed with many in basic/clinical NR (undergraduate/graduate/professional biomedical- health career) pipeline, we expect HSNRP to continue expanding the network of diverse curious researchers, physicians and other health professionals; and improve "neurohealth" literacy through community engagement. Ongoing short- and long-term evaluation includes surveys, database registry, follow-up, and portfolios to document efficacy.