Child Mental Health in HIV-impacted Low-Resource Settings in Developing Countries: Global Research Fellowship

项目摘要/总结 拟议的“发展中国家受艾滋病毒影响的资源匮乏地区的儿童心理健康：全球 研究奖学金”（CHILD-GRF）培训计划将提供最先进的方法培训、指导、 以及为致力于研究事业的有前途的早期职业研究人员提供“实践”研究经验 专注于解决艾滋病毒预防问题以及儿童和青少年心理健康的严重负担 (CAMH) 在艾滋病毒/艾滋病的背景下。总体期望是增加、加强和维持 乌干达是一个受艾滋病毒/艾滋病影响严重的撒哈拉以南非洲 (SSA) 国家。儿童- GRF 的指导方针是： 目标 1. 确定并培训一支由 18 名乌干达 SSA 科学家组成的骨干队伍（每年 6 名以上，超过 3 名） 连续的招聘周期）能够担任外部资助的首席研究员（PI） 研究重点是艾滋病毒综合预防（CHP），解决持续贫困、社区暴力、共同 发生的 CAMH 问题，以及受艾滋病毒影响社区的艾滋病毒护理和预防。该计划将 建立并提供：(a) 实质性领域的多学科培训以及识别和识别方法 在发展中国家受艾滋病毒影响的资源匮乏地区治疗 CAMH，采用以下干预措施： 已在文化上适应 SSA，并通过为期 3 年的针对 SSA 背景的方法培训 圣路易斯华盛顿大学 (WUSTL) 的夏季强化培训，由多学科教师领导，(b) 强化指导计划和培训基础设施，促进长期研究合作 来自北半球和南半球的高级研究人员和导师； (c) 实践学习机会 通过夏季之间的活动，包括实地考察 NIH 资助的研究项目和重点研究中心 受艾滋病毒/艾滋病严重影响的社区的艾滋病毒预防和心理健康干预措施； (d) 资金 用于试点研究； (e) 试点研究、手稿准备和资助的技术支持和同行评审 更大型研究的申请。目标 2. 汇集来自北半球和世界各地的忠诚导师网络 全球南方确保对乌干达有前途的新调查员进行高质量培训，他们将集中精力 针对艾滋病毒的文化一致性干预措施的研究，重点是共存的 CAMH 和 CHP 对中低收入国家（包括SSA）具有潜在影响。目标 3：描绘成功的关键因素 对乌干达新调查员的指导和培训，对新调查员有潜在影响 重点关注中低收入国家（包括 SSA）的 CAMH 和艾滋病毒预防干预措施。 CHILD-GRF 具有结构化的 6- 为期一周的强化高级暑期培训计划。每个研究员都将与 WUSTL 的一位导师配对， 乌干达。严格的项目评估将跟踪个人研究员的进展和项目的成功。这个 应用程序与福格蒂加强各机构科学能力的战略重点相一致 中低收入国家开展与其国家不断演变的艾滋病毒流行相关的艾滋病毒研究。

Project Abstract/Summary The proposed “Child Mental Health in HIV-impacted Low-resource settings in Developing countries: Global Research Fellowship” (CHILD-GRF) training program will provide state-of-the-art methods training, mentoring, and “hands-on” research experience to promising early career researchers committed to research careers focused on addressing HIV prevention and the serious burden of child and adolescent mental health (CAMH) in the context of HIV/AIDS. The overall expectation is to increase, strengthen, and sustain the capacity of research institutions in Uganda, a sub-Saharan African (SSA) country heavily affected by HIV/ AIDS. CHILD- GRF is guided by: Aim 1. Identify and train a cadre of 18 SSA scientists from Uganda (6 per year over 3 consecutive recruitment cycles) capable of serving as a Principal Investigators (PIs) on extramurally funded studies focused on combination HIV prevention (CHP) addressing persistent poverty, community violence, co- occurring CAMH problems, and HIV care and prevention in HIV-impacted communities. The program will establish and provide: (a) multi-disciplinary training in substantive areas and methods for identification and treatment of CAMH in HIV-impacted low-resource settings in developing countries, applying interventions that have been culturally adapted to SSA along with training in methods focused on SSA context through a 3-year summer intensive training at Washington University in St. Louis (WUSTL), led by multidisciplinary faculty, (b) an intensive mentorship program and training infrastructure that fosters long-term research collaboration with senior researchers and mentors from the global north and the global south; (c) hands-on learning opportunities through activities between summers, including site visits to NIH funded research projects and centers focused on HIV prevention and mental health interventions in communities heavily impacted by HIV/AIDS; (d) funding for pilot studies; and (e) technical support and peer review for pilot studies, manuscript preparations, and grant applications for larger studies. Aim 2. Bring together a network of committed mentors from the global north and the global south to ensure quality training for promising new investigators from Uganda who would focus their research on culturally-congruent interventions addressing HIV with an emphasis on co-existing CAMH and CHP with potential implications for LMICs, including SSA. Aim 3: Delineate key factors that underlie successful mentorship and training of new investigators from Uganda, with potential implications for new investigators focused on CAMH and HIV-prevention interventions in LMICs, including SSA. CHILD-GRF has a structured, 6- week intensive advanced summer training program. Each fellow will be paired with a mentor from WUSTL and Uganda. A rigorous program evaluation will track individual fellow progress and program success. This application is aligned with Fogarty's strategic priority of strengthening the scientific capacity of institutions in LMICs to conduct HIV research relevant to the evolving HIV epidemic in their country.