Pediatric Heart Network Clinical Research Center - Medical University of South Carolina

儿科心脏网络临床研究中心 - 南卡罗来纳医科大学

• 批准号: 10544149
• 负责人: ANDREW M ATZ
• 金额: $ 32.89万
• 依托单位: MEDICAL UNIVERSITY OF SOUTH CAROLINA
• 依托单位国家: 美国
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-01-01 至 2024-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10544149
• 关键词: Academic Medical Centers; Adult; Affect; Arrhythmia; Cardiovascular system; Caring; Child; Childhood; Clinical Research; Clinical Research Protocols; Collaborations; Data Coordinating Center; Databases; Dedications; Development; Elements; Enrollment; Evaluation; Faculty; Funding; Goals; Grant; Heart; Heart Diseases; Individual; Inflammatory; Information Dissemination; Intervention; Lead; Medical; Methodology; Multi-site clinical study; Multicenter Studies; Nurses; Operative Surgical Procedures; Participant; Patients; Pediatric cardiology; Registries; Research; Research Infrastructure; Research Personnel; Resources; South Carolina; Supervision; Techniques; Training; Universities; Work; cardiac muscle disease; clinical center; congenital heart disorder; data submission; improved; novel; participant retention; pediatric cardiologist; programs; randomized, clinical trials; recruit; trial planning

PROJECT SUMMARY The Children's Heart Program of South Carolina is a statewide consortium of pediatric cardiologists, who care for >95 % of the 4.7 million residents in the state. This consortium has all the critical elements for a center to be a successful collaborator in the Pediatric Heart Network (PHN): adequate patient volume, established clinical research infrastructure, a track record of outstanding subject enrollment, and a dedication to hypothesis driven research. These elements have allowed MUSC to be a highly successful and administratively active participant in the PHN and one of only 5 core centers to be continuously funded since its inception in 2001. Furthermore, MUSC faculty have participated as Pl's in a wide variety of non-PHN multicenter studies, often acting as the lead investigator. MUSC faculty also currently direct numerous local clinical research protocols. The combined resources of patient volume, research infrastructure and dedication have enabled MUSC to be among the top subject enrollers in the PHN.

项目概要 南卡罗来纳州儿童心脏计划是一个由儿科心脏病专家组成的全州联盟，他们关心 该州 470 万居民中的 95% 以上。该联盟拥有中心所需的所有关键要素 成为儿科心脏网络 (PHN) 的成功合作者：已建立足够的患者数量 临床研究基础设施、优秀受试者注册记录以及对假设的奉献 驱动的研究。这些要素使得 MUSC 成为一个非常成功且管理活跃的机构。 PHN 的参与者，也是自 2001 年成立以来仅有的 5 个持续资助的核心中心之一。 此外，MUSC 教师作为 Pl 参与了各种非 PHN 多中心研究，通常是 担任首席调查员。 MUSC 教师目前还指导许多当地的临床研究方案。 患者数量、研究基础设施和奉献精神的综合资源使 MUSC 成为 跻身 PHN 顶尖学科招生者之列。

项目成果

Longitudinal Follow-Up of Children With HLHS and Association Between Norwood Shunt Type and Long-Term Outcomes: The SVR III Study.

• DOI: 10.1161/circulationaha.123.065192
• 发表时间: 2023-10-24
• 期刊: CIRCULATION
• 影响因子: 37.8
• 作者: Goldberg, Caren S.;Trachtenberg, Felicia;Gaynor, J. William;Mahle, William T.;Ravishankar, Chitra;Schwartz, Steven M.;Cnota, James F.;Ohye, Richard G.;Gongwer, Russell;Taylor, Michael;Paridon, Stephen;Frommelt, Peter C.;Afton, Katherine;Atz, Andrew M.;Burns, Kristin M.;Detterich, Jon A.;Hill, Kevin D.;Cabrera, Antonio G.;Lewis, Alan B.;Pizarro, Christian;Shah, Amee;Sharma, Binu;Newburger, Jane W.
• 通讯作者: Newburger, Jane W.

Comparison of echocardiographic measurements to invasive measurements of diastolic function in infants with single ventricle physiology: a report from the Pediatric Heart Network Infant Single Ventricle Trial.

单心室生理学婴儿的超声心动图测量与侵入性舒张功能测量的比较：儿科心脏网络婴儿单心室试验的报告。

• DOI: 10.1017/s1047951119001859
• 发表时间: 2019
• 期刊: Cardiology in the young
• 影响因子: 1
• 作者: Goudar,SumaP;Zak,Victor;Atz,AndrewM;Altmann,Karen;Colan,StevenD;Falkensammer,ChristineB;Friedberg,MarkK;Frommelt,Michele;Hill,KevinD;Hsu,DaphneT;Levine,JamiC;Margossian,Renee;Mart,ChristopherR;Sticka,Joshua;Shrader,Pe
• 通讯作者: Shrader,Pe

Relation of Norwood Shunt Type and Frequency of Arrhythmias at 6 Years (from the Single Ventricle Reconstruction Trial).

诺伍德分流类型与 6 年心律失常频率的关系（来自单心室重建试验）。

• DOI: 10.1016/j.amjcard.2021.12.056
• 发表时间: 2022
• 期刊: The American journal of cardiology
• 作者: Cain,Nicole;Saul,JPhilip;Gongwer,Russell;Trachtenberg,Felicia;Czosek,RichardJ;Kim,JeffreyJ;Kaltman,JonathonR;LaPage,MartinJ;Janson,ChristopherM;Singh,AnoopK;Hill,AllisonC;Landstrom,AndrewP;Thacker,Deepika;Niu,MaryC;De
• 通讯作者: De

The Pediatric Heart Network Scholar Award programme: a unique mentored award embedded within a multicentre network.

• DOI: 10.1017/s1047951118000483
• 发表时间: 2018-06
• 期刊: Cardiology in the young
• 影响因子: 1
• 作者: Minich LL;Pemberton VL;Shekerdemian LS;Millar MM;Newburger JW;Glatz AC;Graham EM;Czosek RJ;Pasquali SK;Seed M;Border WL
• 通讯作者: Border WL