Administrative Core

摘要，行政核心 “中间的丘脑：多区域神经回路的计算”提案旨在结合专业知识 理论上，分子神经科学，现代高通量解剖学，细胞和突触神经生理学，以及 定量行为背景下的大规模神经生理学。总体项目由五个项目组成， 重点关注信息如何从皮层下区域流经丘脑，以控制皮层活动模式 从而塑造行为；分子科学核心、数据科学核心和行政核心 5 个 PI 和两个协作站点。实现该项目的潜力需要强有力的行政领导 整合和协同纽约大学和艾伦大学合作研究人员的努力 研究所。 行政核心将提供整个项目的结构、领导和运营管理 推进理解皮层下→丘脑→皮层回路中神经计算的目标。这将 包括项目管理、战略规划、进度报告、财务管理和支持 协作与沟通。行政核心将创建一个基础设施，促进 成员之间的沟通与协作，以及收集外部研究的投入 通过组建外部科学顾问委员会来促进社区的发展。整个项目将形成一个指导 委员会和项目团队监督协作、标准化和准时的数据生成、数据 分析和公共数据共享过程。项目管理最佳实践，例如里程碑、进度 将应用报告和跟踪、协作软件程序和责任矩阵来确保 实现绩效目标和里程碑、优化沟通以及资源利用和 优先顺序。此外，管理核心将促进跨项目的联合数据分析工作和 机构。生产高质量的工具和数据资源，严格的标准化和质量控制 做法将被所有成员采纳。最后，行政核心将实施和维持财政和 所有成员的分包商管理流程，管理出版和作者决定以及 冲突解决。随着整个基础设施的实施，我们预计该项目和 它产生的资源将对揭示信号路由的逻辑产生广泛而有意义的影响 皮质下区域至额叶皮质丘脑。

Summary, Administrative Core The proposal “Thalamus in the middle: computations in multi-regional neural circuits” aims to combine expertise in theory, molecular neuroscience, modern high-throughput anatomy, cellular and synaptic neurophysiology, and large-scale neurophysiology in the context of quantitative behavior. The overall project consists of five Projects, focusing on how information flows from subcortical areas, through thalamus, to control cortical activity modes and thereby shape behavior; a Molecular Science Core, a Data Science Core, and an Administrative Core with 5 PIs and two collaborative sites. Realizing the potential of this project requires strong administrative leadership to integrate and synergize efforts across the collaborating researchers at New York University and the Allen Institute. The Administrative Core will provide the structure, leadership and operational management of the overall project to advance the goal of understanding neural computation in subcortex → thalamus → cortex circuits. This will include project management, strategic planning, progress reporting, fiscal management, and support for collaboration and communication. The Administrative Core will create an infrastructure that fosters communication and collaboration among the members, as well as garnering input from the external research community through the formation of an External Scientific Advisory Board. The overall project will form a Steering Committee and Project Teams to oversee the collaborative, standardized, and on-time data generation, data analysis, and public data sharing process. Project management best practices, such as milestones, progress reporting and tracking, collaborative software programs, and a responsibility matrix will be applied to ensure achievement of performance objectives and milestones, optimized communication, and resource utilization and prioritization. In addition, the Administrative Core will foster joint data analysis efforts across projects and Institutions. To produce a high-quality tools and data resource, rigorous standardization and quality control practices will be adopted by all members. Finally, the Administrative Core will implement and maintain fiscal and subcontractor management processes for all members, manage publication and authorship decisions and conflict resolution. With the implementation of this entire infrastructure, we anticipate that this project and the resources it produces will have a broad and meaningful impact on uncovering the logic of signal routing from subcortical areas to the frontal cortex thalamus.