Understanding HIV/STD Risk and Enhancing PrEP Implementation Messaging in a Diverse Community-Based Sample of Gay, Bisexual, and Other Men Who Have Sex with Men in a Transformational Era

在转型时代的同性恋、双性恋和其他男男性行为者的多元化社区样本中了解 HIV/性病风险并加强 PrEP 实施信息

• 批准号: 10552339
• 负责人: Patrick Sean Sullivan
• 金额: $ 145.6万
• 依托单位: EMORY UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-08-01 至 2026-07-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10552339
• 关键词: Understanding; HIV; STD; Risk; Enhancing

Abstract The prevention of HIV in the United States is in a transformational era. In just a decade since the first finding of efficacy for daily oral PrEP, there is a proliferation of new PrEP agents, including long-acting injectable PrEP, and regimens, including “event-driven” (also called 2-1-1) PrEP. There has also been new knowledge about the impact of antiretrovirals (ARVs) for treatment of HIV, and an emergent understanding that people living with HIV who take ARVs and maintain a suppressed viral load are incapable of transmitting HIV to their sexual partners. In this context, the idea of “protected” sex – which historically meant sex protected by condoms – has become much more complex. To understand men’s preferences for prevention products and strategies and what choices are being made by men with varying risk profiles, we will enroll a prospective cohort of 1275 of men who have sex with men (MSM) in Atlanta, Detroit and San Diego and follow the cohort for two years. Each participant will have 8 quarterly quantitative assessments, including discreet choice experiments; a subset of MSM will be engaged in a qualitative assessments (focus group discussions and individual in-depth interviews) to help with message development and refinement. HIV and STI testing will be provided in alternating 6-month windows. Rapid reporting of results will produce actionable reports following each assessment wave. This project will serve as a dynamic source of data about the evolving patterns of use and preference for PrEP among MSM.

摘要