Design and Implementation of An Intervention to Improve Prediabetes Management in Primary Care

改善初级保健糖尿病前期管理的干预措施的设计和实施

• 批准号: 10553673
• 负责人: Eva Tseng
• 金额: $ 19.87万
• 依托单位: JOHNS HOPKINS UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-04-10 至 2025-01-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10553673
• 关键词: Address; Adult; Award; Awareness; Baltimore; Behavioral; Cardiovascular system; Caring; Centers for Disease Control and Prevention (U.S.); Chronic Disease; Clinic; Clinical; Clinical Pathways; Clinical Protocols; Clinical Research; Clinical Trials; Complications of Diabetes Mellitus; Computerized Medical Record; Data; Data Analytics; Data Collection; Data Set; Data Sources; Databases; Development; Development Plans; Diabetes Mellitus; Diabetes prevention; Diagnosis; Effectiveness; Eligibility Determination; Environment; Evidence based intervention; Funding; Goals; Grant; Guidelines; Health system; Healthcare; Healthcare Systems; Human Resources; Incidence; Individual; Institution; Internal Medicine; Intervention; Intervention Studies; Intervention Trial; Interview; Knowledge; Leadership; Learning; Learning Module; Life Style; Life Style Modification; Link; Medical; Mentored Patient-Oriented Research Career Development Award; Mentors; Metformin; Methodology; Methods; Microvascular Dysfunction; Modeling; Monitor; National Institute of Diabetes and Digestive and Kidney Diseases; Neuropathy; Online Systems; Outcome; Patients; Performance; Persons; Pharmaceutical Preparations; Play; Population; Prediabetes syndrome; Premature Mortality; Prevention Research; Prevention trial; Primary Care; Provider; Public Health; Public Health Schools; Recommendation; Reporting; Research; Research Personnel; Research Training; Resources; Retrospective cohort study; Risk; Role; Scientist; Services; Testing; Time; Training; Training Activity; Translating; United States; United States National Institutes of Health; Universities; Visit; Woman; Work; analytical method; cardiovascular disorder risk; career; career development; design; diabetes management; diabetes prevention program; diabetes risk; diagnostic criteria; epidemiology study; evidence base; evidence based guidelines; follow-up; group intervention; high risk; implementation evaluation; implementation facilitators; implementation intervention; implementation science; implementation tool; improved; informant; insurance claims; insurance plan; lifestyle intervention; medical schools; meetings; patient engagement; pilot test; placebo group; pragmatic intervention; prevent; primary care clinic; primary care practice; primary care provider; primary care setting; professor; programs; research and development; routine practice; screening; skills; success; successful intervention; therapy design; weight loss program

PROJECT SUMMARY/ABSTRACT Diabetes prevention is crucial for reducing the public health burden of diabetes in the United States. 84 million U.S. adults have prediabetes but 90% are undiagnosed. The NIH has prioritized finding efficient ways to translate outcomes achieved in diabetes prevention trials into routine healthcare practice. The National Diabetes Prevention Program recognizes lifestyle change programs meeting specific metrics that help prevent or delay diabetes. However, an effective model for engaging health systems and primary care providers in facilitating screening, testing and referral to these programs is lacking. There is currently no systematic approach to prediabetes management in the primary care setting, but it is essential for addressing the burden of diabetes. To address this need, we propose the following interrelated Specific Aims: 1) To conduct a retrospective cohort study to describe longitudinal primary care provider practices around the diagnosis and treatment of prediabetes using a linked claims and electronic medical record (EMR) dataset, 2) To conduct key informant interviews with stakeholders relevant to diabetes prevention, including leadership from health care system/clinics, insurance plan leaders, providers and patients, to identify barriers and facilitators to implementation, 3) To design and pilot test the diabetes prevention clinical pathway within a primary care clinic in Baltimore, MD, and evaluate its effectiveness on provider screening and intervention, and patient engagement in diabetes prevention over a period of 12 months. Dr. Eva Tseng is an Assistant Professor in the Division of General Internal Medicine and a clinical researcher at The Johns Hopkins University School of Medicine. Her long-term career goal is to become an independent clinician-investigator conducting pragmatic intervention studies with a focus on improving the prevention of diabetes in primary care. The proposed career development plan includes didactic and research training activities that will substantially build her skills in developing and implementing an intervention. These will include training in implementation science, clinical trial methods, quantitative data analytic methods for large claims/EMR databases, as well as qualitative data collection and analytic methods. This training will occur in the rich training environment of the Johns Hopkins Medical Institutions, including the Bloomberg School of Public Health and the Welch Center for Prevention, Epidemiology, and Clinical Research. She will receive guidance from her outstanding team of mentors and advisors with expertise in the methodologies needed for conducting the planned research, and a track record of mentoring and funding. The award and protected time will allow Dr. Tseng to build an independent NIH-funded research career and become a leader in pragmatic approaches to improve the prevention of diabetes in primary care with potential applications to other chronic diseases.

项目总结/摘要 糖尿病预防对于减少美国糖尿病的公共卫生负担至关重要。0.84亿 美国成年人有糖尿病前期，但90%未被诊断出来。美国国立卫生研究院已经优先寻找有效的方法来翻译 将糖尿病预防试验中取得的成果纳入常规医疗实践。国家糖尿病 预防计划认可满足特定指标的生活方式改变计划，有助于预防或延迟 糖尿病然而，让卫生系统和初级保健提供者参与促进 这些方案缺乏筛查、检测和转诊。目前还没有系统的方法来 在初级保健环境中进行糖尿病前期管理，但这对于解决糖尿病负担至关重要。 为了满足这一需求，我们提出了以下相互关联的具体目标：1）进行回顾性队列研究 描述初级保健提供者在糖尿病前期诊断和治疗方面的纵向实践的研究 使用链接的索赔和电子病历（EMR）数据集，2）进行关键线人访谈， 与糖尿病预防相关的利益相关者，包括医疗保健系统/诊所、保险公司的领导 计划领导者、提供者和患者，以确定实施的障碍和促进者，3）设计和试点 在马里兰州巴尔的摩的一家初级保健诊所内测试糖尿病预防临床路径，并评估其 提供者筛查和干预的有效性，以及患者在糖尿病预防中的参与， 为期12个月。 博士伊娃曾是一个助理教授在一般内科和临床研究员， 约翰霍普金斯大学医学院。她的长期职业目标是成为一名独立的 临床医生-调查员进行务实的干预研究，重点是改善预防 糖尿病在初级保健 拟议的职业发展计划包括教学和研究培训活动， 培养她制定和实施干预措施的技能。这些将包括执行方面的培训 科学，临床试验方法，大型索赔/EMR数据库的定量数据分析方法，以及 定性数据收集和分析方法。此培训将在丰富的培训环境中进行， 约翰霍普金斯医疗机构，包括彭博公共卫生学院和韦尔奇中心， 预防、流行病学和临床研究。她将得到她优秀团队的指导， 导师和顾问，在进行计划的研究所需的方法方面具有专业知识，以及 指导和资助的跟踪记录。奖金和受保护的时间将允许曾博士建立一个 独立的NIH资助的研究生涯，并成为务实的方法，以提高领导者 在初级保健中预防糖尿病，并可能应用于其他慢性病。

项目成果

Identification of Prediabetes Discussions in Unstructured Clinical Documentation: Validation of a Natural Language Processing Algorithm.

• DOI: 10.2196/29803
• 发表时间: 2022-02-24
• 期刊: JMIR medical informatics
• 影响因子: 3.2
• 作者: Schwartz JL;Tseng E;Maruthur NM;Rouhizadeh M
• 通讯作者: Rouhizadeh M

Clinical Care Among Individuals with Prediabetes in Primary Care: a Retrospective Cohort Study.

• DOI: 10.1007/s11606-022-07412-9
• 发表时间: 2022-12
• 期刊: Journal of general internal medicine
• 影响因子: 5.7
• 作者: Tseng E;Durkin N;Clark JM;Maruthur NM;Marsteller JA;Segal JB
• 通讯作者: Segal JB

Engaging Payors and Primary Care Physicians Together in Improving Diabetes Prevention.

• DOI: 10.1007/s11606-022-07788-8
• 发表时间: 2023-03
• 期刊: JOURNAL OF GENERAL INTERNAL MEDICINE
• 影响因子: 5.7
• 作者: Tseng, Eva;Meza, Kayla;Marsteller, Jill A.;Clark, Jeanne M.;Maruthur, Nisa M.;Smith, Katherine
• 通讯作者: Smith, Katherine

Analysis of Primary Care Provider Electronic Health Record Notes for Discussions of Prediabetes Using Natural Language Processing Methods.

使用自然语言处理方法分析初级保健提供者电子健康记录笔记以讨论糖尿病前期。

• DOI: 10.1007/s11606-020-06400-1
• 发表时间: 2021
• 期刊: Journal of general internal medicine
• 影响因子: 5.7
• 作者: Tseng,Eva;Schwartz,JessicaL;Rouhizadeh,Masoud;Maruthur,NisaM
• 通讯作者: Maruthur,NisaM