Indiana Medical Scientist/Engineer Training Program

摘要 印第安纳大学医学院(IUSM)医学科学家/工程师培训计划(MSTP) 培训了一批不同的医生-科学家/工程师，以进行严谨、创新和临床相关的研究 研究。毕业生是生物医学科学的领军人物，他们正在应用科学技术的快速进步 发现人类疾病的新疗法。我们的目标是与NIGMS合作，支持 这项计划，要求我们队列的25%是T32资助的实习生。我们的具体目标是1)招募 来自不同背景的有竞争力的团队，他们对研究和患者都有坚定的承诺 护理；2)培训学生进行基础和翻译研究以及医学方面的培训，从而使毕业生具备 成功；以及3)拥有医学博士和博士学位的研究生，他们是最好的住院医生的竞争对手 以及谁将成为学术界和 工业。我们MSTP的一个独特方面是它与韦尔登学校的长期伙伴关系和协同作用 普渡大学生物医学工程(BME)；该项目已经毕业了20名内科工程师。 第二个关键特征是我们注重多样性、公平性和包容性(DEI)。在这方面，我们许多积极的 招募和教养计划，包括一个由Burroughs-Wellcome基金新拨款支持的计划，已经 使美国成为Dei招聘的领头羊，特别是在中西部。在过去的五年里，我们22%的预科学生 来自代表性不足和/或处境不利的群体，50%是妇女。我们有108个 具有良好的培训和研究记录以及约1.3亿美元赠款支持的教师。该计划的 卓越体现在申请数量的增加上，从2007年的99份增加到2021年的293份。MSTP是最顶尖的 IUSM的培训优先事项，由200万美元的直接支助和几笔针对MSTP的捐赠提供资金， 其中包括来自礼来公司基金会的1000万美元。我们的项目通过为学生提供卓越的 课程结构、课程内容、导师、研究设施和临床资源。Iusm是 印第安纳州唯一的对抗疗法医学院：它是美国最大的医学院，拥有最大的 卫生系统。我们的领导人把学生福利、Dei培训和安全放在首位。培训是必需的 负责任的研究行为和在研究中的再现性和所有毕业生都发表了第一作者 文件。在过去的五年里，我们100%的毕业生都进入了全美一流的实习项目 国家，包括研究密集型驻地实习(例如，PSTP)。从长远来看，毕业生在以下方面取得了成功 学术界和工业界。在此，我们建议与NIH合作，培养下一代卓越的 印第安纳州的医生-科学家和医生-工程师。

Abstract The Indiana University School of Medicine (IUSM) Medical Scientist/Engineer Training Program (MSTP) has trained a diverse cohort of physician-scientists/engineers to conduct rigorous, innovative and clinically relevant research. Graduates are leaders in the biomedical sciences who are applying the rapid advances in scientific discovery to the development of new treatments for human disease. We aim to partner with NIGMS to support this program, requesting that 25% of our cohort be trainees on the T32 grant. Our Specific Aims are 1) to recruit a competitive cohort from diverse backgrounds who have a strong commitment both to research and to patient care; 2) to train students in basic and translational research and in medicine, thus equipping graduates to succeed; and 3) to graduate students with MD and PhD degrees who are competitive for the best residency positions; and who will become leading, innovative physician-scientists/physician-engineers in academics and industry. A unique aspect of our MSTP is its long-standing partnership and synergy with the Weldon School of Biomedical Engineering (BME) at Purdue University; the program has already graduated 20 physician-engineers. A second key feature is our focus on diversity, equity, and inclusion (DEI). In this regard, our many active recruitment and feeder programs, including one supported by a new Burroughs-Wellcome Fund grant, have made us leaders in DEI recruitment, particularly in the Midwest. In the last five years 22% of our matriculants have come from underrepresented and/or disadvantaged groups, and 50% have been women. We have 108 preceptors with strong training and research records and ~$130 million in grant support. The program’s excellence is reflected in the increase in applications, from 99 in 2007 to 293 in 2021. The MSTP is the top training priority for IUSM, funded with $2 million in direct support and several MSTP-specific endowments, including $10 million from the Eli Lilly Foundation. Our program equips students to excel by providing superior programmatic structure, curricular content, mentorship, research facilities and clinical resources. IUSM is Indiana’s only allopathic medical school: it is the largest medical school in the nation, with one of the largest health systems. Our leaders prioritize student welfare, DEI training and safety. Training is required in the responsible conduct of research and in research reproducibility and all graduates have published first author papers. In the last five years, 100% of our graduates matched into top-ranked residency programs across the nation, including research-intensive residencies (e.g., PSTPs). Long term, graduates are successful in academics and in industry. Here, we propose to partner with NIH to train the next generation of exceptional physician-scientists and physician-engineers in Indiana.