Multidisciplinary Research Training in Sleep Science
Multidisciplinary Research Training in Sleep Science
批准号:
10555855
负责人:
INDU A AYAPPA
金额:
$19.36万
依托单位国家:
美国
项目类别:
财政年份:
2023
资助国家:
美国
项目状态:
未结题
起止时间:
2023-02-01 至 2028-01-31
中文摘要
项目总结/文摘
英文摘要
Project Summary/Abstract
The significance of sleep and circadian disorders on public health is broad because of its effects on physical and mental
health. The high prevalence of these disorders makes it critical that a robust pipeline exists for new investigators to
tackle the challenge of understanding the mechanisms involved, their impact on cardiovascular, metabolic, pulmonary
and neurodegenerative systems and develop and test interventions. Faculty at Icahn School of Medicine (ISMMS) and
New York University Grossman School of Medicine (NYU) from multiple departments (sleep medicine, pulmonary,
psychiatry, neuroscience, radiology, population health, cardiology, and biostatistics) have been involved in collaborative
basic and clinical research in sleep and circadian science for several decades. Our training program will build on the
foundation of successful mentored research and training programs (e.g. PRIDE institute at NYU) with experienced, well-
funded investigators who have demonstrated a strong commitment for career development. The areas of current
research include (but are not limited to) (i) basic biology of the circadian clock, (ii) translational research on the role of
sleep on memory, (iii) clinical patient oriented research evaluating physiology of obstructive sleep apnea (OSA), its
treatment and evaluation of outcomes of OSA on cardiovascular and brain health (iv) developing simulation and web
based tools to assist teaching sleep physiology. State of the art physiological and imaging techniques (cardiac CT
imaging, PET/MR brain imaging, Alzheimer’s disease biofluid biomarkers) are employed, and include subjects across the
age spectrum (pediatric to elderly populations) and minority populations. We will leverage access to the existing training
infrastructure at the two institutions along with the experience of successful collaborations over the past 10 years
between multidisciplinary faculty at the two institutions and incorporate translational content to train post-doctoral
fellows. The aim of this 5-year program is to recruit and train a total of 6 postdoctoral candidates (physician scientists or
PhD graduates). Trainees will participate in a 2-3 year program during which time they are assigned to a mentoring
team, comprised of a primary, secondary and peer mentor. Mentors are nationally recognized investigators with
expertise in guiding mentees in developing their careers and in submitting successful grant applications. Trainees will
implement an Individual Development Plan, use a combination of existing conferences, didactic courses and technology-
assisted multi-institutional workshops to acquire professional, laboratory based skills and training in responsible conduct
of research. Trainees will have access to the broad training and research support resources of the two institutions
including those of the CTSI/CTSA. Measurable outcomes will include trainee publications, presentations, and grant
applications. Mentees’ achievements for 10 years post program will also be evaluated and include academic leadership
positions, career awards, federal and non- federal grants and engagement in mentoring activities. The Sleep Science T32
Program addresses the need for sleep and circadian researchers and facilitates their transition to independence.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Disturbed sleep and cardiovascular outcomes in World Trade Center Responders
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批准号:10749277
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项目类别:
-
资助金额:$50.0万
-
财政年份:2023
-
负责人:INDU A AYAPPA
-
依托单位:
Role of Sleep Apnea in Cognition and Alzheimer's Disease Biomarkers in WTC Responders
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批准号:10459199
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项目类别:
-
资助金额:$59.35万
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财政年份:2021
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负责人:INDU A AYAPPA
-
依托单位:
Role of Sleep Apnea in Cognition and Alzheimer's Disease Biomarkers in WTC Responders
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批准号:10314853
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项目类别:
-
资助金额:$59.38万
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财政年份:2021
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负责人:INDU A AYAPPA
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依托单位:
Role of Sleep Apnea in Cognition and Alzheimer's Disease Biomarkers in WTC Responders
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批准号:10624882
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项目类别:
-
资助金额:$59.23万
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财政年份:2021
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负责人:INDU A AYAPPA
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依托单位:
Mentoring Research in the Physiology of Sleep Disordered Breathing
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批准号:8581978
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项目类别:
-
资助金额:$9.33万
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财政年份:2013
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负责人:INDU A AYAPPA
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依托单位:
Mentoring Research in the Physiology and Consequences of Sleep Disordered Breathing
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批准号:10255499
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项目类别:
-
资助金额:$10.92万
-
财政年份:2013
-
负责人:INDU A AYAPPA
-
依托单位:
Mentoring Research in the Physiology and Consequences of Sleep Disordered Breathing
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批准号:10634675
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项目类别:
-
资助金额:$10.92万
-
财政年份:2013
-
负责人:INDU A AYAPPA
-
依托单位:
Mentoring Research in the Physiology of Sleep Disordered Breathing
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批准号:9234136
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项目类别:
-
资助金额:$9.33万
-
财政年份:2013
-
负责人:INDU A AYAPPA
-
依托单位:
Mentoring Research in the Physiology of Sleep Disordered Breathing
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批准号:8703762
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项目类别:
-
资助金额:$9.33万
-
财政年份:2013
-
负责人:INDU A AYAPPA
-
依托单位:
Mentoring Research in the Physiology and Consequences of Sleep Disordered Breathing
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批准号:9751019
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项目类别:
-
资助金额:$10.33万
-
财政年份:2013
-
负责人:INDU A AYAPPA
-
依托单位:
Mentoring Research in the Physiology and Consequences of Sleep Disordered Breathing
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批准号:10430236
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项目类别:
-
资助金额:$10.92万
-
财政年份:2013
-
负责人:INDU A AYAPPA
-
依托单位:
Mentoring Research in the Physiology of Sleep Disordered Breathing
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批准号:9319784
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项目类别:
-
资助金额:$9.33万
-
财政年份:2013
-
负责人:INDU A AYAPPA
-
依托单位:
Obstructive Sleep Apnea in WTC Responders: Role of Nasal Pathology
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批准号:8690363
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项目类别:
-
资助金额:$50.08万
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财政年份:2013
-
负责人:INDU A AYAPPA
-
依托单位:
Obstructive Sleep Apnea in WTC Responders: Role of Nasal Pathology
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批准号:8471845
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项目类别:
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资助金额:$49.0万
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财政年份:2012
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负责人:INDU A AYAPPA
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依托单位:
Obstructive Sleep Apnea in WTC Responders: Role of Nasal Pathology
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批准号:8724478
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项目类别:
-
资助金额:$99.97万
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财政年份:2012
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负责人:INDU A AYAPPA
-
依托单位:
Obstructive Sleep Apnea in WTC Responders: Role of Nasal Pathology
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批准号:8858414
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项目类别:
-
资助金额:$99.97万
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财政年份:2012
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负责人:INDU A AYAPPA
-
依托单位:
Obstructive Sleep Apnea in WTC Responders: Role of Nasal Pathology
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批准号:8827936
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项目类别:
-
资助金额:$0.92万
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财政年份:2012
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负责人:INDU A AYAPPA
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依托单位:
Relating sleep disordered breathing to daytime function
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批准号:7842024
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项目类别:
-
资助金额:$16.57万
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财政年份:2009
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负责人:INDU A AYAPPA
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依托单位:
AUTOMATED (AI) ANALYSIS OF SLEEP DISORDERED BREATHING
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批准号:7718390
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项目类别:
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资助金额:$0.13万
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财政年份:2008
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负责人:INDU A AYAPPA
-
依托单位:
VALIDATION OF APNEA RISK EVALUATION SLEEP SCORING
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批准号:7605783
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项目类别:
-
资助金额:$0.12万
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财政年份:2007
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负责人:INDU A AYAPPA
-
依托单位:
海外基金